1890 KOCH, Robert Heinrich Hermann (1843 – 1910)
Weitere Mittheilungen über ein Heilmittel gegen Tuberkulose.
In 1890, Koch announced the discovery of tuberculin, a substance derived from tubercle bacilli, which he thought was capable of arresting bacterial development in-vitro and in animals. This news gave rise to tremendou…
GMN 2332 · https://historyofmedicine.com/id/3068
1907 PIRQUET, Clemens Peter Freiherr von (1874 – 1929)
Der diagnostische Wert der kutanen Tuberkulinreaktion bei der Tuberkulose des Kindesalters auf Grund von 100 Sektionen.
Introduction of Pirquet’s test – a cutaneous reaction employed in the diagnosis of tuberculosis.
GMN 2338 · https://historyofmedicine.com/id/3080
1908 MORO, Ernst (1874 – 1951)
Ueber eine diagnostische verwertbare Reaktion der Haul auf Einreibung mit Tuberkulinsalbe.
Moro’s percutaneous tuberculin reaction, employed as a diagnostic measure.
GMN 2339 · https://historyofmedicine.com/id/3083
1908 WOLFF-EISNER, Alfred (1877 – 1948)
Die kutane und konjunktivale Tuberkulinreaktion, ihre Bedeutung für Diagnostik und Prognose der Tuberkulose.
Wolff-Eisner’s conjunctival tuberculin reaction.
GMN 2340 · https://historyofmedicine.com/id/3086
1908 MANTOUX, Charles (1877 – 1947)
Intradermo-réaction de la tuberculine.
Mantoux’s intradermal tuberculin skin test.
GMN 2341 · https://historyofmedicine.com/id/3089
1908 SCHICK, Béla (1877 – 1967)
Kutanreaktion beil Impfung mit Diphtherietoxin.
The Schick test for the determination of susceptibility to diphtheria.
GMN 5065 · https://historyofmedicine.com/id/5896
1908 MENDEL, Felix (1862 – 1925)
Die von Pirquet'sche Hautreaktion und die intravenöse Tuberkulinbehandlung.
First publication on the The Mantoux test or Mendel–Mantoux test (also known as the Mantoux screening test, tuberculin sensitivity test, Pirquet test, or PPD test for purified protein derivative) is a tool for screeni…
GMN 12385 · https://historyofmedicine.com/id/14611
1913 SCHICK, Béla (1877 – 1967)
Die Diphtherietoxin – Hautreaktion des Menschen als Vorprobe der prophylaktischen Diphtherieheilseruminjektion.
Schick developed his test for use as an indication as to whether or not prophylactic injections of antitoxin are necessary in children already exposed to diphtheria. English translation in J. Mt. Sinai Hosp., 1938, 5,…
GMN 5066 · https://historyofmedicine.com/id/5897
1918 SCHULTZ, Werner (1878 – 1944); CHARLTON, Willy (1889 – )
Serologische Beobachtungen am Scharlachexanthem.
Schultz–Charlton reaction.
GMN 5081 · https://historyofmedicine.com/id/5943
1919 MITSUDA, Kensuke (1876 – 1964)
On the value of a skin reaction to a suspension of leprous nodules.
Mitsuda (lepromin) reaction. English translation by the author in Int. J. Leprosy, 1953, 21, 347-58.
GMN 2440 · https://historyofmedicine.com/id/2914
1919 –1920 GOETSCH, Emil (1883 – 1963)
Epinephrin hypersensitiveness test in the diagnosis of hyperthyroidism.
Goetsch devised a skin reaction test for use in the diagnosis of hyperthyroidism
GMN 3850 · https://historyofmedicine.com/id/4883
1924 KASSOWITZ, Karl Erhard (1886 – 1978)
Ueber cutane Hautreaktion mittels Diphtherie-Toxin zum Nachweis der Diphtherie-Immunität.
The “scratch test”, a cutaneous reaction for determination of susceptibility to diphtheria.
GMN 5069 · https://historyofmedicine.com/id/5907
1924 DICK, George Frederick (1881 – 1967); DICK, Gladys Rowena Henry (1881 – 1963)
A skin test for susceptibility to scarlet fever.
The “Dick test” for the determination of individual susceptibility to scarlet fever.
GMN 5082 · https://historyofmedicine.com/id/5946
1928 MCKINNON, Neil E. (1894 – 1985); DEFRIES, Robert Davies (1889 – 1975)
The reaction of the skin of the normal rabbit following intradermal injection of material from smallpox lesions: the specificity of this reaction and its application as a diagnostic test.
McKinnon’s diagnostic test.
GMN 5434 · https://historyofmedicine.com/id/7416
1932 AUGUSTINE, Donald Leslie (1895 – ); THEILER, Hans (1894 – )
Precipitin and skin tests as aids in diagnosing trichinosis.
Intradermal test for trichinosis.
GMN 5351.1 · https://historyofmedicine.com/id/6880
1934 SEIBERT, Florence Barbara (1897 – 1991)
The isolation and properties of the purified protein derivative of tuberculin
Purification of tuberculin (PPD). By the 1940s Seibert's PPD was the international standard for tuberculin tests.
GMN 12387 · https://historyofmedicine.com/id/14614
1937 VOLLMER, Hermann (1896 – 1959); GOLDBERGER, Esther White (1905 – )
A new tuberculin patch test.
GMN 2348 · https://historyofmedicine.com/id/3118
1950 FRAPPIER, Armand (1904 – 1991); GUY, Roland (1913 – )
A new and practical B.C.G. skin test (the B.C.G. scarification test) for the detection of the total tuberculous allergy.
GMN 2352 · https://historyofmedicine.com/id/3132
1951 HEAF, Frederick Roland George (1894 – 1973)
The multiple-puncture tuberculin test.
The Heaf multiple-puncture tuberculin test.
GMN 2352.1 · https://historyofmedicine.com/id/3135
