1632 SEVERINO, Marco Aurelio [SEVERINUS] (1580 – 1656)

De recondita abscessuum natura.

The first textbook of surgical pathology. It treats of all kinds of swelling under the term “abscess” and describes neoplasms of the genital organs and sarcoma of bones. Tumors of the breast are classified into four g…

GMN 2273 · https://historyofmedicine.com/id/2841

1822 MOTT, Valentine (1785 – 1865)

Case of osteo-sarcoma in which the right side of the lower jaw was removed successfully after tying the carotid artery.

Mott resected the entire half of the bone, necessitating a disarticulation at the temporo-mandibular joint.

GMN 4447 · https://historyofmedicine.com/id/6356

1824 ROGERS, David L. (1799 – 1877)

Case of osteo-sarcoma of the superior maxillary bone, with the operation for its removal.

Rogers removed nearly all of the upper jaw. Operation performed in 1810.

GMN 4449 · https://historyofmedicine.com/id/56

1828 SYME, James (1799 – 1870)

Case of osteo-sarcoma of the lower jaw.

Syme’s operation of excision of the lower jaw for osteosarcoma.

GMN 4453 · https://historyofmedicine.com/id/60

1828 MOTT, Valentine (1785 – 1865)

An account of a case of osteo-sarcoma of the left clavicle, in which exsection of that bone was successfully performed.

Valentine Mott was an outstanding figure in American surgery during the first half of the 19th century. A pupil of Astley Cooper, he particularly distinguished himself in vascular surgery and in operations involving t…

GMN 4452 · https://historyofmedicine.com/id/132

1879 GROSS, Samuel Weissel (1837 – 1889)

Sarcoma of the long bones; based upon a study of one hundred and sixty-five cases.

First comprehensive work on bone sarcoma.

GMN 4346 · https://historyofmedicine.com/id/5723

1901 PEPPER, William Jr. (1843 – 1898)

A study of congenital sarcoma of the liver and suprarenal. With report of a case.

Pepper’s type of adrenal medullary tumor.

GMN 3866 · https://historyofmedicine.com/id/4917

1903 SCHMIDT, Martin Benno (1863 – 1949)

Die Verbreitungswege der Karzinome und die Beziehung generalisierter Sarkome zu den leukämischen Neubildungen.

Schmidt supported the theory of the hematogenous origin of carcinoma metastases.

GMN 2629 · https://historyofmedicine.com/id/3209

1907 HUTCHISON, Sir Robert (1871 – 1960)

On suprarenal sarcoma in children with metastases in the skull.

Hutchison’s tumors.

GMN 3868 · https://historyofmedicine.com/id/4920

1910 CARREL, Alexis (1873 – 1944); BURROWS, Montrose Thomas (1884 – 1947)

Cultures de sarcome en dehors de l’organisme.

Using the Rous chicken sarcoma, Carrel and Burrows were the first to grow tumor tissue in vitro.

GMN 2636 · https://historyofmedicine.com/id/3234

1910 ROUS, Francis Peyton (1879 – 1970)

A transmissible avian neoplasm (sarcoma of the common fowl).

Original description of the chicken sarcoma (Rous sarcoma). Rous demonstrated that sarcomatous tumors in hens could be transmitted to normal hens by the injection of cell-free filtrates (virus) of the original tumor. …

GMN 2637 · https://historyofmedicine.com/id/3238

1920 BULLOCK, Frederick Dabney (1878 – 1937)

A preliminary report on the experimental production of sarcoma of the liver of rats.

Proof that cancer can be caused by a parasite, Cysticercus fasciolaris, the larval stage of Taenia crassicolis. With M. R. Curtis and G. L. Rohdenberg. See also Proc. N.Y. path. Soc., 1920, 20, 149-75.

GMN 2645.1 · https://historyofmedicine.com/id/3283

1921 EWING, James (1866 – 1943)

Diffuse endothelioma of bone.

Ewing described a form of bone sarcoma (“Ewing’s sarcoma”), usually involving the shaft of long bones.

GMN 4388 · https://historyofmedicine.com/id/5947

1925 CODMAN, Ernest Amory (1869 – 1940)

Bone sarcoma, an interpretation of the nomenclature used by the Committee on the Registry of Bone Sarcoma of the American College of Surgeons.

GMN 4393 · https://historyofmedicine.com/id/5977

1926 BARNARD, William George (1892 – 1956)

The nature of the “oat-celled sarcoma” of the mediastinum.

An important study of the histology of “oat-celled sarcoma” which Barnard showed to be primary carcinoma of the lung.

GMN 3201 · https://historyofmedicine.com/id/4298

1927 KOLODNY, Anatole (1892 – 1948)

Bone sarcoma. The primary malignant tumors of bone and the giant cell tumor.

Based on material collected by the Registry of Bone Sacrcoma in Boston since its foundation in 1921.

GMN 4394 · https://historyofmedicine.com/id/5979

1931 GESCHICKTER, Charles Freeman (1901 – 1987); COPELAND, Murray Marcus (1902 – 1981)

Tumors of bone.

GMN 4400 · https://historyofmedicine.com/id/6017