1984 HAUSEN, Harald zur (1936 – ); GISSMANN, Lutz (1949 – ); IKENBERG, Hans (1954 – ); BOSHART, M.; KLEINHEINZ, A.; SCHEURLEN, W.

A new type of papillomavirus DNA, its presence in genital cancer biopsies and in cell lines derived from cervical cancer.

Zur Hausen and colleagues discovered HPV18 as a cause of cervical cancer. With the discovery of HPV18, and HPV16, which zur Hausen and team discovered in 1983, zur Hausen discovered the viruses causing about 75% of hu…

GMN 12664 · https://historyofmedicine.com/id/14908

1990 KING, Mary-Claire (1946 – )

Linkage of early-onset familial breast cancer to Chromosome 17q21.

King showed that breast cancer can be inherited due to mutations in the Breast cancer type 1 susceptibility protein, a protein that in humans is encoded by the BRAC1 gene. BRCA1 is a human tumor suppressor gene (also …

GMN 13966 · https://historyofmedicine.com/id/16268

1994 SKOLNICK, Mark Henry (1946 – ); MIKI, Yoshio; SHATTUCK-EIDENS, Donna; ET AL

A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1.

Discovery of the BRCA1 gene using the technique of restriction fragment length polymorphism (RFLP). (Thanks to Juan Weiss for this reference and its interpretation.)

GMN 14015 · https://historyofmedicine.com/id/16322

2013 ADEY, Andrew C.; BURTON, Joshua N.; KLITZMAN, Jacob O.; ET AL

The haplotype-resolved genome and epigenome of the aneuploidy HeLa cancer cell line.

Adey and colleagues sequenced the haplotype-resolved whole genome of the HeLa cancer cell line. This showed a highly rearranged region at chromosome 8q24.21, where an integration locus of the HPV (human papillomavirus…

GMN 14101 · https://historyofmedicine.com/id/16412

2014 MARANI, Enrico; KOCH, Wijnand F. R. M.

The Pelvis: Structure, gender and society.

"This book offers a critical review of the pelvic sciences—past, present and future—from an anatomical and physiological perspective....The book starts with a “construction plan” of the pelvis and shows its structural…

GMN 10629 · https://historyofmedicine.com/id/12822