1917 JACKSON, Chevalier (1865 – 1958)
Endothelioma of the right bronchus removed by peroral bronchoscopy.
First reported case.
GMN 3194 · https://historyofmedicine.com/id/4243
1917 FORSSELL, Carl Gustaf (1876 – 1950)
Översikt över resultaten av kräftbehandling vid Radiumhemmet i Stockholm 1910-1915.
The Stockholm method of radium treatment of cancer of the uterus, as carried out at the Radiumhemmet, Stockholm, follows the technique devised by Forssell.
GMN 6125 · https://historyofmedicine.com/id/7602
1919 EWING, James (1866 – 1943)
Neoplastic diseases.
Fourth edition, 1940.
GMN 2644 · https://historyofmedicine.com/id/3276
1920 BULLOCK, Frederick Dabney (1878 – 1937)
A preliminary report on the experimental production of sarcoma of the liver of rats.
Proof that cancer can be caused by a parasite, Cysticercus fasciolaris, the larval stage of Taenia crassicolis. With M. R. Curtis and G. L. Rohdenberg. See also Proc. N.Y. path. Soc., 1920, 20, 149-75.
GMN 2645.1 · https://historyofmedicine.com/id/3283
1921 COUTARD, Henri (1876 – 1950)
Un cas d’épithélioma spino-cellulaire de la région latérale du pharynx, avec adénopathie angulo-maxillaire, guéri depuis six mois par la röntgenthérapie.
Carcinoma of pharynx cured by the Coutard method of Röntgen therapy.
GMN 3196 · https://historyofmedicine.com/id/4263
1921 EWING, James (1866 – 1943)
Diffuse endothelioma of bone.
Ewing described a form of bone sarcoma (“Ewing’s sarcoma”), usually involving the shaft of long bones.
GMN 4388 · https://historyofmedicine.com/id/5947
1922 LABBÉ, Ernest Marcel (1870 – 1939); ET AL
Crises solaires et hypertension paroxystique en rapport avec une tumeur surrénale.
First full description of chromaffin cell tumors of the adrenal medulla. With J. Tinel and E. Doumer.
GMN 3871 · https://historyofmedicine.com/id/4924
1922 HANDLEY, William Sampson (1872 – 1962)
Cancer of the breast and its treatment. 2nd ed.
Sampson Handley advanced the theory that in mammary cancer metastasis is due to extension along lymphatic vessels – “lymphatic permeation” – and not to dissemination byway of the blood stream. The book was first publi…
GMN 5782 · https://historyofmedicine.com/id/6833
1922 DUNHILL, Sir Thomas Peel (1876 – 1957)
Removal of intrathoracic tumours by the trans-sternal route.
Dunhill’s operation for the removal of intrathoracic tumors.
GMN 5630.1 · https://historyofmedicine.com/id/7220
1924 KENNAWAY, Sir Ernest Laurence (1881 – 1958)
The formation of a cancer-producing substance from isoprene (2-methyl-butadiene).
Kennaway produced carcinogenic tars by submitting acetylene or isoprene to high temperatures in an atmosphere of hydrogen, thus proving that some carcinogens are pure hydrocarbons.
GMN 2646 · https://historyofmedicine.com/id/3288
1925 GYE, William Ewart (1884 – 1952)
The aetiology of malignant new growths.
Gye advanced the theory that an ultramicroscopic virus combined with an intrinsic chemical factor were concerned in the production of the Rous sarcoma.
GMN 2647 · https://historyofmedicine.com/id/3291
1925 BARNARD, Joseph Edwin (1870 – 1949)
The microscopical examination of filterable viruses associated with malignant new growths.
Barnard supported, with photomicrographs, Gye’s theory concerning the origin of cancer.
GMN 2648 · https://historyofmedicine.com/id/3294
1925 DAWSON, James Walker (1870 – 1927)
The melanomata, their morphology and histogenesis. A study of cell origins and transformations, with a critical discussion on aspects of tumour growth, and a clinical review.
The first exhaustive monograph on the pathology of melanoma. Also issued as a separate monograph (Edinburgh: Oliver & Boyd, 1925).
GMN 2649 · https://historyofmedicine.com/id/3299
1925 CODMAN, Ernest Amory (1869 – 1940)
Bone sarcoma, an interpretation of the nomenclature used by the Committee on the Registry of Bone Sarcoma of the American College of Surgeons.
GMN 4393 · https://historyofmedicine.com/id/5977
1926 CUSHING, Harvey Williams (1869 – 1939); BAILEY, Percival (1892 – 1973)
A classification of the tumors of the glioma group on a histogenetic basis with a correlated study of prognosis.
From 1922 to 1925 Bailey undertook extensive pathological and histological studies of brain tumors, and based on cellular configuration, he created a classification system of thirteen categories. In 1927 he reduced th…
GMN 4608 · https://historyofmedicine.com/id/568
1926 BENDIEN, Salomo Gerhard Tekla (1872 – 1942)
Haemagglutinegehalte van het bloedserum bij carcinoompatiënten.
Bendien test for the diagnosis of cancer. He published books in German and English on this subject in 1931. Modification by E. C. Lowe, Brit. med. J., 1932, 2, 1060.
GMN 2650 · https://historyofmedicine.com/id/3301
1926 WARBURG, Otto Heinrich (1883 – 1970)
Ueber den Stoffwechsel der Tumoren.
In his important studies of the metabolism of tumors, Warburg was first to observe that malignant tissue utilizes glucose by glycolysis, whether or not oxygen is available (aerobic glycolysis). English translation, 1930.
GMN 2651 · https://historyofmedicine.com/id/3305
1926 BARNARD, William George (1892 – 1956)
The nature of the “oat-celled sarcoma” of the mediastinum.
An important study of the histology of “oat-celled sarcoma” which Barnard showed to be primary carcinoma of the lung.
GMN 3201 · https://historyofmedicine.com/id/4298
1926 ABRIKOSOV, Aleksi Ivanovitch (1875 – 1955)
Über Myome, ausgehend von der quergestreiften willkürlichen Muskulatur.
“Abrikosov’s tumor”, granular-cell myoblastoma.
GMN 4151.1 · https://historyofmedicine.com/id/5853
1926 LANE-CLAYPON, Janet Elizabeth (1877 – 1967)
A further report on cancer of the breast, with special reference to its associated antecedent conditions.
First modern case-control study.
GMN 5782.1 · https://historyofmedicine.com/id/6835
1927 WILDER, Russell Morse (1885 – 1959); ET AL
Carcinoma of the islands of the pancreas; hyperinsulinism and hypoglycemia.
R. M. Wilder, F. N. Allan, M. H. Power, and H. E. Robertson reported the occurrence of carcinoma with hyperinsulinism. They also reported the first operation for hyperinsulinism performed on December 2, 1926 by Willia…
GMN 3972 · https://historyofmedicine.com/id/5280
1927 KOLODNY, Anatole (1892 – 1948)
Bone sarcoma. The primary malignant tumors of bone and the giant cell tumor.
Based on material collected by the Registry of Bone Sacrcoma in Boston since its foundation in 1921.
GMN 4394 · https://historyofmedicine.com/id/5979
1927 ARINKIN, Mikhail (1876 – 1948)
"Methodology of examining bone marrow in live patients, with haemopoietic disease."
Needle puncture of bone marrow biopsy. (In Russian.) German account in Folia haemat. (Lpz.), 1929, 38, 233-40. English translation from the German in Bick, Classics of orthopaedics, 339-44.
GMN 3088 · https://historyofmedicine.com/id/8947
1927 MAYO, Charles Horace (1865 – 1939)
Paroxysmal hypertension with tumor of retroperitoneal nerve. Report of a case.
First resection of a pheochromocytoma in America, and the second in the world, by the co-founder of the Mayo Clinic. In 1926 César Roux of Lausanne did the first resection of this rare type of tumor.
GMN 12266 · https://historyofmedicine.com/id/14483
1928 SLYE, Maud (1879 – 1954)
Cancer and heredity.
By selective breeding over a period of 15 years, Slye produced generations of mice absolutely resistant to, or particularly susceptible to, cancer. She demonstrated that resistance is a Mendelian dominant and suscepti…
GMN 2652 · https://historyofmedicine.com/id/3307
1928 WIDERØE, Rolf (1902 – 1996)
Über ein neues Prinzip zur Herstellung höher Spannungen.
RF-powered linear accelerator.
GMN 2652.1 · https://historyofmedicine.com/id/3310
1930 PIRQUET, Clemens Peter Freiherr von (1874 – 1929)
Allergie des Lebensalters, die bösartigen Geschwülste.
Important study of the age and sex incidence of cancer.
GMN 2653 · https://historyofmedicine.com/id/3315
1930 THOMSON, Sir St Clair (1859 – 1943); COLLEDGE, Lionel (1883 – 1948)
Cancer of the larynx.
Thomson’s technique in the laryngofissure procedure for intrinsic cancer of the larynx was published in his Diseases of the nose and throat, London, 1911, pp. 732-37.
GMN 3326 · https://historyofmedicine.com/id/4564
1931 GESCHICKTER, Charles Freeman (1901 – 1987); COPELAND, Murray Marcus (1902 – 1981)
Tumors of bone.
GMN 4400 · https://historyofmedicine.com/id/6017
1931 CHEATLE, Sir George Lenthal (1865 – 1951); CUTLER, Max (1899 – 1984)
Tumours of the breast. Their pathology, symptoms, diagnosis, and treatment.
GMN 5784 · https://historyofmedicine.com/id/6840
1931 NYLÉN, Carl-Olof (1892 – 1978)
A clinical study on positional nystagmus in cases of brain tumour.
GMN 4611.2 · https://historyofmedicine.com/id/8931
1931 CUSHING, Harvey Williams (1869 – 1939)
Experiences with the cerebellar astrocytomas. A critical review of seventy-six cases.
Cushing's most extensive contribution to pediatric neurosurgery concerned his operative experience with these tumors (often benign) that most frequently occur in childhood.
GMN 11188 · https://historyofmedicine.com/id/13385
1932 –1934 FISCHL, Viktor; SCHLOSSBERGER, Hans (1887 – 1960)
Handbuch der Chemotherapie. 2 vols.
GMN 1921 · https://historyofmedicine.com/id/2705
1932 COOK, Sir James Wilfred (1900 – 1975)
The production of cancer by pure hydrocarbons.
Discovery of the carcinogenic properties of dibenzanthracene compounds. With I. Hieger, E. L. Kennaway, and W. V. Mayneord.
GMN 2654 · https://historyofmedicine.com/id/3319
1932 PANCOAST, Henry Khunrath (1875 – 1939)
Superior pulmonary sulcus tumor. Tumor characterized by pain. Horner’s syndrome, destruction of bone and atrophy of hand muscles.
“Pancoast’s tumor.”
GMN 2655 · https://historyofmedicine.com/id/3323
1932 SHOPE, Richard Edwin (1901 – 1966)
A transmissible tumor-like condition in rabbits.
Shope papilloma virus (SPV), a benign infectious tumor due to a virus. This was the first mammalian tumor virus discovered. Full text from PubMedCentral at this link. See also Shope, "Infectious Papillomatosis of Rabb…
GMN 2656 · https://historyofmedicine.com/id/3328
1932 KEYNES, Sir Geoffrey Langdon (1887 – 1982)
The radium treatment of carcinoma of the breast.
Keynes’s successes with radium in breast cancer established this method of conservative treatment. His first paper on the subject, with the same title, was published in St. Barth. Hosp. Rep., 1927, 60, 91-95.
GMN 5786 · https://historyofmedicine.com/id/6846
1932 LACASSAGNE, Antoine Marcellin Bernard (1884 – 1971)
Apparition de cancers de la mamelle chez la souris mâle, soumise à des injections de folliculine.
Demonstration of the carcinogenic effect of ovarian hormone.
GMN 2657 · https://historyofmedicine.com/id/6852
1933 HAAGENSEN, Cushman Davis (1900 – 1990)
An exhibit of important books, papers, and memorabilia illustrating the evolution of the knowledge of cancer.
GMN 2662 · https://historyofmedicine.com/id/3448
1933 GRAHAM, Evarts Ambrose (1883 – 1957); SINGER, Jacob Jesse (1882 – 1954)
Successful removal of entire lung for carcinoma of the bronchus.
First reported case: April 5, 1933.
GMN 3205 · https://historyofmedicine.com/id/4326
1933 CHAOUL, Henri (1887 – 1964); ADAM, Albert
Die Röntgen-Nahbestrahlung maligner Tumoren.
Chaoul therapy.
GMN 4007 · https://historyofmedicine.com/id/5114
1933 ADAIR, Frank Earl (1887 – 1981)
Plasma cell mastitis–a lesion simulating mammary carcinoma.
First description of plasma-cell mastitis.
GMN 5788 · https://historyofmedicine.com/id/6854
1933 –1939 REGAUD, Claudius (1870 – 1940)
Considérations sur la radiothérapie des cancers cervico-uterins, d’après l’experience et les résultats acquis à l’Institut du Radium de Paris.
The Paris method of radium treatment of cancer of the uterus was devised by Regaud.
GMN 6131 · https://historyofmedicine.com/id/7635
1933 SCHILLER, Walter (1887 – 1960)
Early diagnosis of carcinoma of the cervix.
Schiller’s test for carcinoma of the cervix.
GMN 6132 · https://historyofmedicine.com/id/7637
1935 WHIPPLE, Allen Oldfather (1881 – 1963); ET AL
Treatment of carcinoma of the ampulla of Vater.
Pancreaticoduodenectomy for cancer of pancreas. With W. B. Parsons and C. R. Mullins.
GMN 3659.1 · https://historyofmedicine.com/id/4789
1936 BITTNER, John Joseph (1904 – 1961)
Some possible effects of nursing on the mammary gland tumor incidence in mice.
Bittner’s “milk factor,” the murine mammary tumor involved in the transmission of cancer in mice. See also Amer. J. clin. Path., 1937, 7, 430-35.
GMN 2658 · https://historyofmedicine.com/id/3333
1937 BONSER, Georgiana May (1898 – 1979)
The carcinogenic action of oestrone: induction of mammary carcinoma in female mice of a strain refractory to the spontaneous development of mammary tumours.
With L. H. Stickland and K. I. Connal.
GMN 2659 · https://historyofmedicine.com/id/3339
1937 BRUNSCHWIG, Alexander (1901 – 1969)
Resection of head of pancreas and duodenum for carcinoma – pancreatoduodenectomy.
See also the same journal, 1943, 77, 581-84.
GMN 3660 · https://historyofmedicine.com/id/4804
1939 BLALOCK, Alfred (1899 – 1964); ET AL
Myasthenia gravis and tumors of the thymic region. Report of a case in which the tumor was removed.
First deliberate treatment of myasthenia gravis by thymectomy, with M. F. Mason, H. J. Morgan, and S. S. Riven.
GMN 4771 · https://historyofmedicine.com/id/1422
1939 LAWRENCE, John Hundale (1904 – 1991); ET AL
Studies on leukemia with the aid of radioactive phosphorus.
Therapeutic use of radioactive isotopes for the treatment of leukemia. John H. Lawrence was the brother of Ernest Orlando Lawrence, inventor of the cyclotron; John Lawrence also worked at the Lawrence Berkeley Nationa…
GMN 3098 · https://historyofmedicine.com/id/3792
