1642 BONDT, Jacob de [Jacobus Bontius] (1592 – 1631)
De medicina Indorum.
Bontius was probably the first to regard tropical medicine as an independent branch of medical science. He spent the last four years of his life in the Dutch East Indies, and his book incorporates the experience he ga…
GMN 2263 · https://historyofmedicine.com/id/2816
1652 TULP, Nicolaes (1593 – 1674)
Observationes medicae.
One of the earliest accounts of beri-beri is on pp. 300-05 of this work. Tulp, notable as the demonstrator in Rembrandt’s “Anatomy Lesson”, was among the first, in the same book, to describe the ileo-caecal valve (“Tu…
GMN 3737 · https://historyofmedicine.com/id/4530
1835 MALCOLMSON, John Grant ( – 1844)
A practical essay on the history and treatment of beriberi.
A classic account, in which the author brought together all that was known about the disease in his day.
GMN 3738 · https://historyofmedicine.com/id/4533
1880 –1884 BÄLZ, Erwin Otto Eduard von (1849 – 1933)
Kakke (Beriberi).
In his important account of beriberi, Baelz dealt with the Tokyo outbreak of 1881.
GMN 3739 · https://historyofmedicine.com/id/4537
1885 KANEHIRO, Takaki (1849 – 1915)
On the cause and prevention of kakke.
Takaki was the first conclusively to show the dietary origin of beriberi. Measures introduced by him resulted in its eradication from the Japanese Navy, where it had previously been a serious problem.
GMN 3740 · https://historyofmedicine.com/id/4541
1890 EIJKMAN, Christiaan (1858 – 1930)
Polyneuritis bij hoenders.
Eijkman produced beriberi experimentally in fowls; from this he was led to conclude that a diet of over-milled rice was the chief cause, both in fowls and humans. Thus his work was of great importance in determining t…
GMN 3741 · https://historyofmedicine.com/id/4544
1901 GRIJNS, Gerrit (1865 – 1944)
Over polyneuritis gallinarum
Grijns succeeded Eijkman as director of the Research Laboratory for Pathological Anatomy and Bacteriology in Batavia. He was the first to adopt the view that beriberi was simply a “deficiency disease”, since he found …
GMN 3742 · https://historyofmedicine.com/id/4549
1907 HOLST, Axel (1860 – 1931)
Experimental studies relating to “ship-beri-beri” and scurvy
Experimental production of scurvy in guinea-pigs. Holst published further papers on the subject in the same journal, 1907, 7, 634-71, and in Z. Hyg., 1912, 72, 1-120, both with Theodor Froelich. Their work made it pos…
GMN 3721 · https://historyofmedicine.com/id/4489
1909 FRASER, Henry (1873 – 1930); STANTON, Sir Ambrose Thomas (1875 – 1938)
An inquiry concerning the etiology of beri-beri.
Studies from the Institute for Medical Research, F. M. S., No. 10. Careful and long-continued experiments on the aetiology of beriberi were carried out by Fraser and Stanton in Malaya.
GMN 3743 · https://historyofmedicine.com/id/4553
1911 –1912 FUNK, Casimir (1884 – 1967)
On the chemical nature of the substance which cures polyneuritis in birds induced by a diet of polished rice.
One of the earliest attempts to isolate what later became known as vitamin B1.See No. 1051. Funk determined the chemical nature of the substance in rice polishings which could cure beriberi.
GMN 1047 · https://historyofmedicine.com/id/582
1913 VEDDER, Edward Bright (1878 – 1952)
Beriberi
Important studies of beri-beri are recorded in this book. After its publication the author made many additional contributions to the literature on the subject.
GMN 3745 · https://historyofmedicine.com/id/4560
1918 HURST, Sir Arthur Frederick (1879 – 1944)
Medical diseases of the war. Second edition
Roughly the first half of this work is on "war neuroses." The second half is on "infective and other disorders," including gas poisoning. Hurst greatly expanded the first section after experience as a neurologist in E…
GMN 8604 · https://historyofmedicine.com/id/10781
1926 JANSEN, Barned Coenraad Petrus (1884 – 1962); DONATH, Willem Frederik (1889 – 1957)
Antineuritische Vitamine.
Isolation of vitamin B1 (aneurine, thiamine), lack of which is a cause of beri-beri.
GMN 1058 · https://historyofmedicine.com/id/4562
1934 WENCKEBACH, Karel Frederik (1864 – 1940)
Das Beriberi-Herz.
Wenckebach wrote a classic account of the heart in beriberi.
GMN 3747 · https://historyofmedicine.com/id/4565
1936 WILLIAMS, Robert Runnels (1886 – 1965); CLINE, Joseph Kalman (1908 – )
Synthesis of vitamin B1.
Synthesis of aneurine.
GMN 1073 · https://historyofmedicine.com/id/756
2000 CARPENTER, Kenneth John (1923 – 2016)
Beriberi, white rice, and vitamin B: A disease, a cause, and a cure.
GMN 12208 · https://historyofmedicine.com/id/14418
