1950 MCCLINTOCK, Barbara (1902 – 1992)

The origin and behavior of mutable loci in maize.

"In the summer of 1944 at Cold Spring Harbor Laboratory, McClintock systematic studies on the mechanisms of the mosaic color patterns of maize seed and the unstable inheritance of this mosaicism.[44] She identified tw…

GMN 12063 · https://historyofmedicine.com/id/14272

1958 MCCLINTOCK, Barbara (1902 – 1992)

The suppressor-mutator system of control of gene action in maize.

In this paper McClintock described a novel mobile genetic element that she called Suppressor-Mutator (Spm), and its complex regulation. She discovered that Spm could switch back and forth between an “inactive” form an…

GMN 13560 · https://historyofmedicine.com/id/15837