1885 SMITH, Andrew (1828 – 1898)
A contribution to South African materia medica, chiefly from plants in use among the natives.
The first edition was a pamphlet of 23 pp. Smith issued a much-expanded second edition with 163 pp., also at Lovedale in 1888, and a further expanded third edition with 262 pp. (Cape Town, 1895). Digital facsimile of …
GMN 9500 · https://historyofmedicine.com/id/11685
1886 BAUMANN, Eugen (1846 – 1896)
Ueber Disulfone.
Preparation of sulphonal.
GMN 1882 · https://historyofmedicine.com/id/2522
1886 UNNA, Paul Gerson (1850 – 1929)
Ichthyol und Resorcin als Repräsentanten der Gruppe reduzierender Heilmittel.
Unna introduced ichthyol and resorcinol into medicine. Supplement to Mh. prakt. Derm., No. 1.
GMN 1883 · https://historyofmedicine.com/id/2528
1886 MAYER, Adolf Eduard Maydolf (1843 – 1942)
Ueber die Mosaikkrankheit des Tabaks.
Mayer was first to describe and name tobacco mosaic disease and to demonstrate its infectious nature, that it could be transferred between plants, similar to bacterial infections. Translation in Phytopathological Clas…
GMN 2503.1 · https://historyofmedicine.com/id/3207
1887 CAHN, Arnold (1858 – ); HEPP, Paul
Sur l’action de l’antifébrine (acétanilide) et de quelques corps analogues.
Introduction of acetanilide (antifebrin).
GMN 1883.2 · https://historyofmedicine.com/id/2433
1887 HINSBERG, Oscar Heinrich Daniel (1857 – 1939); KAST, Alfred (1856 – 1903)
Ueber die Wirkung des Acetphenetidins.
Introduction of phenacetin.
GMN 1883.3 · https://historyofmedicine.com/id/2478
1887 HUCHARD, Henri (1844 – 1910)
L’artério-sclérose subaiguë dans ses rapports avec les spasmes vasculaires et son traitement par la trinitrine (nitroglycérine).
“Huchard’s disease” – continued hypertension causing arteriosclerosis. Huchard did much to develop the knowledge concerning arteriosclerosis and summarized his work in a classic monograph published in 1909.
GMN 2908 · https://historyofmedicine.com/id/4869
1887 NAGAYOSHI, Nagai (1844 – 1929)
Ephedrin.
Isolation of ephedrine from Ephedra distachya.
GMN 1883.1 · https://historyofmedicine.com/id/8942
1887 MILLSPAUGH, Charles Frederick (1854 – 1923)
American medicinal plants; an illustrated and descriptive guide to the American plants used as homoeopathic remedies: Their history, preparation, chemistry and physiological effects. Illustrated by the author.
Plates printed by chromolithography. Digital facsimile from the Internet Archive at this link.
GMN 8716 · https://historyofmedicine.com/id/10894
1888 KAST, Alfred (1856 – 1903)
Sulfonal, ein neues Schlafmittel.
Introduction of sulphonal, previously discovered by Baumann.
GMN 1884 · https://historyofmedicine.com/id/2481
1889 –1891 PETERS, Hermann (1847 – 1920)
Aus pharmazeutischer Vorzeit in Bild und Wort. 2 vols.
Digital facsimile of the 1889 edition from the Internet Archive at this link. Translated into English by William Netter as Pictorial history of ancient pharmacy; with sketches of early medical practice (Chicago, G. P.…
GMN 2036 · https://historyofmedicine.com/id/2187
1889 EMMERICH, Rudolf (1852 – 1914); LÖW, Oscar [Loew] (1844 – 1941)
Bakteriolytische Enzyme als Ursache der erworbenen Immunität und die Heilung von Infectionskrankheiten durch dieselben.
Emmerich and Löw prepared a water-soluble antibiotic substance, pyocyanase, from Pseudomonas pyocanea. It inhibited pathogenic cocci and the organisms responsible for diphtheria, plague, cholera, and typhoid.
GMN 1932.2 · https://historyofmedicine.com/id/2768
1889 MARCELLUS EMPIRICUS, (Marcellus Burdigalensis) (375 – 425); HELMREICH, Georg (1849 – 1921)
Marcelli De medicamentis liber. Edited Georgius Helmreich.
Marcellus's compendium of pharmacological preparations drawing on the work of multiple medical and scientific writers as well as folk remedies and magic. Digital facsimile from the Internet Archive at this link.
GMN 8330 · https://historyofmedicine.com/id/10506
1889 MERCK & CO.
Merck's index of fine chemicals and drugs for the materia medica and the arts: Comprising a summary of whatever chemical products are to-day adjudged as being useful in either medicine or technology, with average values and synonyms affixed; a guide for the physician, apothecary, chemist, and dealer.
First edition of the Merck Manual. Digital facsimile from the Internet Archive at this link.
GMN 9525 · https://historyofmedicine.com/id/11711
1889 VUILLEMIN, Jean Paul (1861 – 1932)
Antibiose et symbiose.
Villemin coined the term antibiosis and advanced the term from an evolutionary viewpoint. Though he presented the concept Villemin did not apply this concept to fight disease. (Thanks to Juan Weiss for this reference.)
GMN 10786 · https://historyofmedicine.com/id/12982
1889 EDKINS, Joseph (1823 – 1905)
Opium: Historical note, or, the poppy in China. Published by order of The Inspector General of Customs.
Though relatively brief (50pp.) this may be the first historical study of opium in English. Text in English and Chinese. Digital facsimile from the Hathi Turst at this link. Reprinted without the Chinese text, Shangha…
GMN 11869 · https://historyofmedicine.com/id/14073
1890 FRASER, Sir Thomas Richard (1841 – 1919)
Strophanthus hispidus; its natural history, chemistry, and pharmacology.
Introduction of Strophanthus hispidus.
GMN 1885 · https://historyofmedicine.com/id/2491
1890 –1893 HOOPER, David (1858 – 1947); DYMOCK, William (1834 – 1892); WARDEN, Charles James Hislop (1851 – 1900)
Pharmacographia indica: A history of the principal drugs of vegetable origin, met with in British India. 3 vols.
On the title page Dymock is identified as "Brigade Surgeon, Bombay Army, Principal Medical Storekeeper to Government." Warden is identified as "Surgeon-Major, Bengal Army, Professor of Chemistry in the Calcutta Medica…
GMN 9246 · https://historyofmedicine.com/id/11428
1891 EHRLICH, Paul (1854 – 1915); GUTTMANN, Paul (1834 – 1893)
Ueber die Wirkung des Methylenblau bei Malaria.
Guttmann and Ehrlich demonstrated methylene blue to be lethal in vitro for the malaria parasite – the beginning of Ehrlich’s work on chemotherapy.
GMN 5241.1 · https://historyofmedicine.com/id/7898
1892 IVANOVSKI, Dmitri Iosifovich (Ivanowski; Iwanowski) (1864 – 1920)
Ueber die Mosaikkrankheit der Tabakspflanze.
The Russian botanist Ivanovski demonstrated that the agent responsible for tobacco mosaic disease could pass through the finest filter then available. This was the starting point of research into the etiology of virus…
GMN 2506.2 · https://historyofmedicine.com/id/3229
1892 GOLGI, Camillo (1844 – 1926)
Azione della chinina sui parasite malarici e sui corrispondente accessi febbrili.
French translation in Arch. ital. Biol., 1892, 17, 456-71.
GMN 5243 · https://historyofmedicine.com/id/7900
1893 ABU MANSUR MUVAFFAK HARAWI (PERSIAN: ابو منصور موفق هروی) (970 – ); ACHUNDOW, Abdul-Chalig
Die pharmakologischen Grundsätze (Liber fundamentorum pharmacologiae) des Abu Mansur Muwaffak bin Ali Harawi zum estern Male nach dem Urtex übersetzt und mit Erklärungen versehen von Abdul-Chalig Achundow aus Baku. (aus Bd. 3 (1893) der Historischen Studien aus dem pharmakologischen Institute der Kaiserlichen Universität Dorpat). 2 vols.
First translation into a modern language.
GMN 8581 · https://historyofmedicine.com/id/10758
1894 CASH, John Theodore (1854 – 1936); DUNSTAN, Sir Wyndham Rowand (1861 – 1949)
The physiological action of the nitrites of the paraffin series, considered in connection with their chemical constitution.
GMN 1886 · https://historyofmedicine.com/id/2497
1894 –1895 PAUL, Benjamin Horatio (1828 – 1902); COWNLEY, Alfred John
The chemistry of ipecacuanha.
Emetine first obtained in pure form.
GMN 1887 · https://historyofmedicine.com/id/2500
1895 ASKANAZY, S
Klinisches über Diuretin.
In 1895 Askanazy proposed diuretin as a remedy for anginal pain.
GMN 2893 · https://historyofmedicine.com/id/4365
1895 JELLIFFE, Smith Ely (1866 – 1945); RUSBY, Henry Hurd (1855 – 1940)
Essentials of vegetable pharmacognosy: A treatise on structural botany, designed especially for pharmaceutical and medical students, pharmacists and physicians. Part 1. The gross structure of plants by Henry H. Rusby. Part 2. The minute structure of plants by Smith Ely Jelliffe.
A detailed guide to the way that botanic drugs were identified and produced in America at the end of the 19th century. Digital facsimile from the Hathi Trust at this link.
GMN 11890 · https://historyofmedicine.com/id/14095
1896 FILEHNE, Wilhelm (1844 – 1927)
Ueber das Pyramidon, ein Antipyrinderivat.
Filehne was responsible for the introduction of amindopyrine (pyramidon).
GMN 1889 · https://historyofmedicine.com/id/2506
1896 GOSIO, Bartolomeo (1863 – 1944)
Ricerche batteriologische e chimiche sulle alterazioni del mais; contributo all’etiologia della pellagra.
First recorded scientific observations on the action of a penicillin. Gosio produced an antibacterial crystalline substance from Penicillium glaucum.
GMN 1932.3 · https://historyofmedicine.com/id/2770
1896 HOLMES, Edward Morrell (1843 – 1930)
Catalogue of the medicinal plants in the Museum of the Pharmaceutical Society of Great Britain.
Digital facsimile from the Internet Archive at this link.
GMN 10382 · https://historyofmedicine.com/id/12574
1897 KRÖNIG, Claus Ludwig Theodor Bernhard (1863 – 1918); PAUL, Theodor (1862 – 1928)
Die chemischen Grundlagen der Lehre von der Giftwirkung und Desinfection.
Krönig and Paul described a new method for the quantitative study of disinfection and laid the foundation of modern knowledge of disinfectants.
GMN 1890 · https://historyofmedicine.com/id/2511
1897 WELLMANN, Max (1863 – 1933); KRATEUAS, [Kratevas, Crateuas, Cratevas; Κρατεύας ὁ Ῥιζότομος] ( – 95)
Krateuas. Von M. Wellmann.
Crateuas was the personal physician of Mithridates VI. Of Pontos. He wrote a three-part herbal book describing the medicinal properties of plants. This work, which was illustrated, is the earliest known herbal book to…
GMN 9015 · https://historyofmedicine.com/id/11194
1898 BERENDES, Julius (1837 – 1914)
Geschichte der Pharmazie.
GMN 2038 · https://historyofmedicine.com/id/2197
1898 DRAGENDORFF, Georg Johann Noel (1836 – 1898)
Die Heilpflanzen der verschiedenen Volker und Zeiten.
GMN 2039 · https://historyofmedicine.com/id/2202
1899 DRESER, Heinrich (1860 – 1925)
Pharmakologisches über Aspirin (Acetylsalicylsäure).
Acetylsalicylic acid (aspirin) introduced into medicine.
GMN 1891 · https://historyofmedicine.com/id/2520
1899 HENSLOW, George (1835 – 1925)
Medical works of the fourteenth century; together with a list of plants recorded in contemporary writings, with their identification.
Digital facsimile from the Internet Archive at this link.
GMN 6519 · https://historyofmedicine.com/id/8090
1900 ANDRÉ-PONTIER, L.
Histoire de la pharmacie.
GMN 2040 · https://historyofmedicine.com/id/2206
1900 MORO, Ernst (1874 – 1951)
Ueber die nach Gram färbbaren Bacillen des Säuglingsstuhles.
Isolation of Lactobacillus acidophilus.
GMN 2515 · https://historyofmedicine.com/id/3263
1900 RUSBY, Henry Hurd (1855 – 1940)
The botanical origin of coca leaves.
GMN 11891 · https://historyofmedicine.com/id/14096
1901 MORTIMER, William Golden (1854 – 1933)
Peru: The history of coca, “the divine plant of the Incas”.
The most comprehensive work on the coca plant and the history of its use by the Incas and their descendants. Reprinted, San Francisco, And/Or Press, 1974.
GMN 2040.1 · https://historyofmedicine.com/id/2212
1901 PARDO DE TAVERA, Trinidad Hermenegildo José Maria Francisco (1857 – 1925); THOMAS, Jerome B. Jr.
The medicinal plants of the Philippines. Translated and revised by Jerome B. Thomas, Jr.
Digital facsimile from the Internet Archive at this link.
GMN 8540 · https://historyofmedicine.com/id/10717
1902 FLEXNER, Simon (1863 – 1946); NOGUCHI, Hideyo (1876 – 1928)
Snake venom in relation to haemolysis, bacteriolysis, and toxicity.
GMN 2110 · https://historyofmedicine.com/id/2613
1902 BERENDES, Julius (1837 – 1914)
Des Pedanios Dioskurides aus Anazarbos Arzneimittellehre in fünf Büchern. Übersetzt und mit Erklärungen Versehen.
Analysis of Dioscordes from the pharmacological standpoint, including determination of his units of measurements, critical in dosage. Digital facsimile from Google Books at this link.
GMN 8569 · https://historyofmedicine.com/id/10746
1902 FÜHNER, Hermann (1871 – 1944)
Lithotherapie: Historische Studien über die medizinische Verwendung der Edelsteine.
Digital facsimile from the Internet Archive at this link.
GMN 8961 · https://historyofmedicine.com/id/11140
c. 1902 EHRLICH, Paul (1854 – 1915)
Ueber die Beziehungen von chemischer Constitution. Vertheilung und pharmakologischer Wirkung: Vortrag, gehalten im Verein für Innere Medicin am 12. December 1898.
In this speech Ehrlich explained how the molecular structure of a drug can define its action and function. It represents his first attempts at modifying the molecular structure of a compound in order to tailor the in …
GMN 12437 · https://historyofmedicine.com/id/14669
1903 RIDEAL, Samuel (1863 – 1929); WALKER, J. T. Ainslie (1868 – 1930)
Standardisation of disinfectants.
Rideal–Walker method for testing disinfectants.
GMN 1893 · https://historyofmedicine.com/id/2532
1903 –1910 DOMÍNGUEZ, Juan Aníbal (1876 – 1946)
Datos par la materia médica Argentina. 2 vols. (Vol. 2: Trabajos de Instituto de Farmacología de la Facultad de Ciencias Médicas de Buenos Aires No. 25).
Digital facsimile from the Internet Archive at this link.
GMN 8543 · https://historyofmedicine.com/id/10720
1904 SCHELENZ, Hermann Emil (1846 – 1922)
Geschichte der Pharmazie
Reprinted Hildesheim, 1964.
GMN 2041 · https://historyofmedicine.com/id/2216
1904 CLOËTTA, Max (1868 – 1940)
Ueber Digalen (Digitoxinum solubile).
Introduction of digalen.
GMN 1893.1 · https://historyofmedicine.com/id/2535
1904 POWER, Frederick Belding (1853 – 1927); GORNALL, Frank Howorth
The constituents of chaulmoogra seeds.
Hydnocarpus wightiana or Chaulmoogra is a tree in the Achariaceae family. The oil from seeds of Hydnocarpus wightiana or Chaulmoogra, a tree in the Achariaceae family, was widely used in Indian medicine and Chinese tr…
GMN 2437 · https://historyofmedicine.com/id/2907
1905 LANGLEY, John Newport (1852 – 1925)
On the reaction of cells and of nerve-endings to certain poisons, chiefly as regards the reaction of striated muscle to nicotine and to curari.
Langley introduced the concept of a receptor substance present in the biological object with which a drug has to interact in order to exert its biological effect. Digital facsimile from PubMedCentral at this link.
GMN 1893.2 · https://historyofmedicine.com/id/2538
