1910 RICKETTS, Howard Taylor (1871 – 1910); WILDER, Russell Morse (1885 – 1959)

The etiology of the typhus fever (tabardillo) of Mexico City. A further preliminary report.

Demonstration of the causal organism of typhus.

GMN 5380.1 · https://historyofmedicine.com/id/7067

1910 –1911 NICOLLE, Charles Jules Henri (1866 – 1936)

Recherches experimentales sur le typhus exanthématique.

Nicolle demonstrated the transmission of typhus by the body louse Pediculus corporis. He also produced the disease in monkeys and guinea-pigs by the injection of infected blood. Preliminary communication in C. R. Acad…

GMN 5384 · https://historyofmedicine.com/id/7096

1915 PROWAZEK, Stanislaus Joseph Matthias von (1875 – 1915)

Ätiologische Untersuchungen über den Flecktyphus in Serbien 1913 und in Hamburg 1914.

Prowazek, like Ricketts and Wilder, demonstrated the specific causal agent in typhus. Like Ricketts he died of the disease.

GMN 5384.1 · https://historyofmedicine.com/id/7107

1916 ROCHA-LIMA, Henrique da (1879 – 1956)

Zur Aetiologie des Fleckfiebers.

Rickettsia prowazeki, cause of epidemic typhus, was first isolated by the Brazilian microbiologist Henrique da Rocha-Lima, who named it after Ricketts and Prowazek, both of whom died of the disease.

GMN 5388 · https://historyofmedicine.com/id/7136

1916 TÖPFER, Hans Willi (1876 – )

Zur Ursache und Uebertragung des Wolhynischen Fiebers.

Isolation of Rickettsia quintana (now called Bartonella quintana) from lice found on patients suffering from trench fever.

GMN 5389 · https://historyofmedicine.com/id/7140

1921 LOEWE, Leo (1896 – ); ET AL

Cultivation of rickettsia-like bodies in typhus fever.

Isolation of Rickettsia prowazeki from the blood. With S. A. Ritter and G. Baehr.

GMN 5392 · https://historyofmedicine.com/id/7151

1922 TODD, John Lancelot (1876 – 1949); WOLBACH, Simeon Burt (1880 – 1954); PALFREY, Francis Winslow (1876 – 1953)

The etiology and pathology of typhus. Being the main report of the Typhus Research Commission of the League of Red Cross Societies to Poland.

The carefully controlled experiments of Wolbach, Todd, and Palfrey eliminated all doubt that R. prowazeki was the causal agent in typhus. Digital facsimile from the U.S. National Library of Medicine at this link.

GMN 5393 · https://historyofmedicine.com/id/7155

1925 FLETCHER, William ( – 1938); LESSLAR, J. E.

Tropical typhus in the Federated Malay States, with a compilation on epidemic typhus.

Bull. Inst. med. Res., F. M. S., No. 2. Drew attention to scrub typhus in Malaya.

GMN 5394 · https://historyofmedicine.com/id/7160

1926 MAXCY, Kenneth Fuller (1889 – 1966)

Clinical observations on endemic typhus (Brill’s disease) in Southern United States.

Maxcy described murine (flea-borne) typhus (“Maxcy’s disease”).

GMN 5396 · https://historyofmedicine.com/id/7169

1928 MOOSER, Hermann (1891 – 1971)

Experiments relating to the pathology and the etiology of Mexican typhus (tabardillo).

Mooser differentiated murine from epidemic typhus. The causative organism was later named Rickettsia mooseri.

GMN 5396.1 · https://historyofmedicine.com/id/7173

1931 DYER, Rollo Eugene (1886 – ); ET AL

Typhus fever. A virus of the typhus type derived from fleas collected from wild rats.

Murine typhus shown to be caused by an organism later named Rickettsia mooseri, transmitted by fleas from rats to man. With A. Rumreich and L. F. Badger.

GMN 5396.2 · https://historyofmedicine.com/id/7175

1931 OGATA, Norio (1883 – )

Aetiologie der Tsutsugamushi-Kiankheit: Rickettsia tsutsugamushi.

Ogata isolated the causal agent of tsutsugamushi disease, Orientia Tsutsugamushi, in 1927.

GMN 5396.3 · https://historyofmedicine.com/id/7176

1937 BURNET, Sir Frank Macfarlane (1899 – 1985); FREEMAN, Mavis Louisa (1907 – 1992)

Experimental studies on the virus of “Q” fever.

Discovery of Rickettsia burneti, causal agent in Q fever.

GMN 5398 · https://historyofmedicine.com/id/7187

1940 LEWTHWAITE, Raymond (1894 – 1972); SAVOOR, S. R. (1900 – 1980)

Rickettsia disease of Malaya. Identity of tsutsugamushi and rural typhus.

Lewthwaite and Savoor showed scrub typhus to be identical to tsutsugamushi fever.

GMN 5398.2 · https://historyofmedicine.com/id/7195

1944 YEOMANS, Andrew (1907 – ); ET AL

The therapeutic effect of para-aminobenzic acid in louse-borne typhus fever.

With J. C. Snyder, E. S. Murray, C. J. D. Zarafonetis, and R. S. Ecke.

GMN 5398.3 · https://historyofmedicine.com/id/7199

1945 FULTON, Forrest (1913 – 1971); JOYNER, L

Cultivation of Rickettsia tsutsugamushi in lungs of rodents. Preparation of a scrub-typhus vaccine.

Scrub-typhus vaccine.

GMN 5399 · https://historyofmedicine.com/id/7205