1861 –1862 BÄRENSPRUNG, Friedrich Wilhelm Felix von (1822 – 1864)
Die Gürtelkrankheit.
Herpes zoster first ascribed to a lesion of the spinal ganglia.
GMN 4640 · https://historyofmedicine.com/id/8866
1884 LANDOUZY, Louis Théophile Joseph (1845 – 1917)
Fièvre zoster etexanthèmes zosteriformes.
Landouzy first suggested the infective nature of herpes.
GMN 4642 · https://historyofmedicine.com/id/717
1892 BÓKAY, János (1858 – 1937)
Das Auftreten von Varizellen unter eigentümlichen Verhältnissen.
Bokay was the first to suggest an etiological relationship between varicella and herpes zoster. See also his paper in Wien. klin. Wschr., 1909, 22, 1323-26.
GMN 5439.1 · https://historyofmedicine.com/id/7460
1900 HEAD, Sir Henry (1861 – 1940); CAMPBELL, Alfred Walter (1868 – 1937)
The pathology of herpes zoster and its bearing on sensory localisation.
Head and Campbell showed herpes zoster to be a hemorrhagic inflammation of the posterior nerve roots and the homologous spinal ganglia.
GMN 4644 · https://historyofmedicine.com/id/724
1905 –1906 TYZZER, Ernest Edward (1875 – 1965)
The histology of the skin lesions in varicella.
Tyzzer was first to recognize inclusion bodies in varicella.
GMN 5440 · https://historyofmedicine.com/id/7464
1907 HUNT, James Ramsay (1872 – 1937)
On herpetic inflammations of the geniculate ganglion: A new syndrome and its complications.
Herpes zoster oticus, also known as Ramsay Hunt syndrome type 2.
GMN 12253 · https://historyofmedicine.com/id/14468
1907 MAREK, József (1868 – 1952)
Multiple Nervenentzündung (Polyneuritis) bei Hühnern.
Marek's disease (fowl paralysis) later named by Peter Biggs, who determined that the disease was caused by Gallid alphaherpesvirus 2, and developed the first generation Marek's disease vaccine.
GMN 13400 · https://historyofmedicine.com/id/15672
1921 LIPSCHÜTZ, Benjamin (1878 – 1931)
Untersuchungen über die Ätiologie der Krankheiten der Herpesgruppe (Herpes zoster, Herpes genitalis, Herpes febrilis).
Lipschütz’s account of herpes virus diseases included identification of the characteristic inclusion bodies (“Zosterkörperchen”).
GMN 2521.1 · https://historyofmedicine.com/id/3300
1925 KUNDRATITZ, Karl (1889 – 1975)
Experimentelle Übertragung von Herpes zoster auf den Menschen und die Beziehungen von Herpes zoster zu Varicellen.
First demonstration of the infectivity of herpes.
GMN 4652 · https://historyofmedicine.com/id/753
1934 SABIN, Albert Bruce (1906 – 1993); WRIGHT, Arthur M.
Acute ascending myelitis following a monkey bite, with the isolation of a virus capable of reproducing the disease.
Herpesvirus simiae (B virus) infection; isolation of the virus.
GMN 4658 · https://historyofmedicine.com/id/770
1953 WELLER, Thomas Huckle (1915 – 2008)
Serial propagation in vitro of agents producing inclusion bodies derived from varicella and herpes zoster.
Isolation of the varicella-herpes virus.
GMN 5440.1 · https://historyofmedicine.com/id/7466
1964 EPSTEIN, Michael Anthony (1921 – ); BARR, Yvonne (1932 – 2016)
Cultivation in vitro of human lymphoblasts from Burkitt’s malignant lymphoma.
Order of authorship in the original publication: Epstein, Barr. Discovery of the Epstein-Barr virus, a human herpes virus causing infectious mononucleosis, and implicated in Burkitt’s lymphoma and other forms of cance…
GMN 2660.17 · https://historyofmedicine.com/id/3410
1964 EPSTEIN, Michael Anthony (1921 – ); BARR, Yvonne (1932 – 2016); ACHONG, Bert Geoffrey (1928 – 1996)
Virus particles in cultured lymphoblasts from Burkitt’s lymphoma.
Order of authorship in the original publication: Epstein, Achong, Barr. Presence of herpes-like virus particles in Burkitt’s tumor cells reported. The Epstein-Barr virus was the first human cancer-causing virus to be …
GMN 2660.18 · https://historyofmedicine.com/id/3414
1967 HENLE, Gertrude Szpingier (1912 – 2006); HENLE, Werner (1910 – 1987); DIEHL, Volker S. (1938 – ); HAUSEN, Harald zur (1936 – ); KOHN, G.
Herpes-type virus and chromosome marker in normal leukocytes after growth with irradiated Burkitt cells.
Hausen and colleagues showed for the first time that a cancer virus (Epstein-Barr virus) can transform healthy cells (lymphocytes) into cancer cells. This showed that viruses can cause cancer cell formation. (Order of…
GMN 12662 · https://historyofmedicine.com/id/14906
1968 HENLE, Gertrude Szpingier (1912 – 2006); HENLE, Werner (1910 – 1987); DIEHL, Volker S. (1938 – )
Relation of Burkitt’s tumor-associated herpes-type virus to infectious mononucleosis.
The Henles and Diehl showed that Epstein-Barr virus is the aetiological agent in infectious mononucleosis.
GMN 5487.1 · https://historyofmedicine.com/id/6427
1970 BIGGS, Peter Martin (1926 – ); ET AL
Field trials with an attentuated cell associated vaccine for Marek's disease.
In 1959 Biggs moved to the Houghton Poultry Research Station (HPRS) to form and head a unit to study lymphoid tumor conditions of the domestic fowl. He gave the name Marek’s disease to one of the tumor conditions, aft…
GMN 2660.26 · https://historyofmedicine.com/id/3438
1973 SHOPE, Thomas
Malignant lymphoma in cottontop marmosets after inoculation with Epstein–Barr virus.
Epstein-Barr virus as a cause of Burkitt’s lymphoma. With D. DeChairo and G. Miller.
GMN 2660.25 · https://historyofmedicine.com/id/3436
1994 CHANG, Yuan (1959 – ); MOORE, Patrick S. (1956 – ); CESARMAN, Ethel; PESSIN, Melissa S.; ET AL
Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma.
Dated December 16, 1994. Order of authorship in the original paper was Chang, Cesarman, Pessin,...Moore. The authors reported a new human herpesvirus associated with Kaposi's sarcoma, and gave it the descriptive name …
GMN 10880 · https://historyofmedicine.com/id/13076
1995 CHANG, Yuan (1959 – ); MOORE, Patrick S. (1956 – )
Detection of herpesvirus-like DNA sequences in Kaposi's sarcoma in patients with and those without HIV infection.
Dated May 4, 1995. Order of authorship in the original publication was Moore, Chang. That the virus causing Kaposi's sarcoma appeared in healthy as well as HIV patients suggested that this virus causes cancer only in …
GMN 10881 · https://historyofmedicine.com/id/13077
1995 CHANG, Yuan (1959 – ); MOORE, Patrick S. (1956 – ); CESARMAN, Ethel; ET AL
Kaposi's Sarcoma-associated herpesvirus-like DNA sequences in AIDS-related body-cavity-based lymphomas.
Chang, Moore and colleagues showed that the virus causing Kaposi's Sarcoma also causes body cavity lymphomas and lymphomatous effusions in humans. (Thanks to Juan Weiss for this reference and its interpretation.)
GMN 10914 · https://historyofmedicine.com/id/13110
1996 BIGONI, B.; DOLCETTI, Riccardo; DE LELLIS, L.; ET AL
Human herpesvirus 8 Is present in the lymphoid system of healthy persons and can reactivate in the course of AIDS.
Dated June 22, 1995. Order of authorship in the original paper was Bigoni, Dolcetti, de Lellis....By this time Kaposi sarcoma-associated herpesvirus (KSHV) was also known as human herpesvirus-8 (HHV-8). The authors wr…
GMN 10882 · https://historyofmedicine.com/id/13078
2014 CRAWFORD, Dorothy H.; JOHANNESSEN, Ingófur; RICKINSON, Alan Bernard
Cancer virus: The story of Epstein-Barr virus.
GMN 11346 · https://historyofmedicine.com/id/13544
