2006 GORE, Albert Arnold Jr. (1948 – )
An inconvenient truth. The planetary emergency of global warming and what we can do about it.
A politician, Gore was one of the first to draw popular attention to climate change. He supplemented the best-selling book with a film and DVD with the same title. Ten years later, recognizing that in spite of its wid…
GMN 14048 · https://historyofmedicine.com/id/16358
2006 SHUBIN, Neil H. (1960 – ); DAESCHLER, Edward B.; JENKINS, Farish Alston (1940 – 2012)
The pectoral fin of Tiktaalik roseae and the origin of the tetrapod limb.
In 2004 Shubin, Daeschler and Jenkins discovered the first well-preserved Tiktaalik fossils in on Ellesmere Island in Nunavut, Canada. Tiktaalik is a non-tetrapod member of Osteichthyes (bony fish) from the late Devon…
GMN 14084 · https://historyofmedicine.com/id/16395
2006 SHUBIN, Neil H. (1960 – ); DAESCHLER, Edward B.; JENKINS, Farish Alston (1940 – 2012)
A Devonian tetrapod-like fish and the evolution of the tetrapod body plan.
The authors showed that: 1) This transitional species had a set of features representing a major departure from the pattern in more primitive sarcopterygian fishes. 2) They presented data to indicate that Tiktaalik li…
GMN 14085 · https://historyofmedicine.com/id/16396
2007 VENTER, John Craig (1946 – )
A life decoded. My genome: My life.
GMN 7434 · https://historyofmedicine.com/id/9606
2007 LANDECKER, Hannah
Culturing life: How cells became technologies.
A history of tissue culture.
GMN 7881 · https://historyofmedicine.com/id/10053
2007 NASH, Linda (1962 – )
Inescapable ecologies: A history of environment, disease, and knowledge.
"Among the most far-reaching effects of the modern environmental movement was the widespread acknowledgment that human beings were inescapably part of a larger ecosystem." This book provides a "history of “ecological”…
GMN 11303 · https://historyofmedicine.com/id/13501
2007 NENE, Vishvanath M.; WORTMAN, Jennifer Russo; LAWSON, Daniel; ET AL
Genome sequence of Aedes aegypti, a major arbovirus vector.
Order of authorship in the original publication: Nene, Wortman, Lawson.... Sequence of the genome of the mosquito that transmits Zika, Yellow fever, Dengue, Chikungunya, etc. (Thanks to Juan Weiss for this reference a…
GMN 11338 · https://historyofmedicine.com/id/13536
2007 HORVATH, Philippe (1970 – ); BARRANGOU, Rodolphe; FREMAUX, Christophe; DEVEAU, Hélène
CRISPR provides acquired resistance against viruses in prokaryotes.
Horvath and his team provided key details of the extremely complex mechanisms involved in CRISPR's function as an immune system for bacteria against bacteriophages. Analogous to Pasteur's heroic role in saving the Fre…
GMN 11843 · https://historyofmedicine.com/id/14047
2007 VENTER, John Craig (1946 – ); LEVY, Samuel; SUTTON, Granger G. III; NG, Pauline G.; ET AL
The diploid genome sequence of an individual human.
The first genome sequence of a single human (Craig Venter), including analysis and comments on his genetic markers, and their possible medical and prognosticating implications. (Order of authorship in the original pub…
GMN 12965 · https://historyofmedicine.com/id/15212
2007 YAMANAKA, Shinya (1962 – ); TAKAHASHI, Kazutoshi; TANABE, Koji; OHNUKI, Mari
Induction of pluripotent stem cells from adult human fibroblasts by defined factors.
Yamanaka (Nobel Prize 2012) and colleagues demonstrated the generation of Induced Pluripotent Stems Cells (iPS) from adult human dermal fibroblasts with the same 4 mice factors they used in GM 13287. By overexpressing…
GMN 14063 · https://historyofmedicine.com/id/16374
2008 LEY, Timothy J.; MARDIS, Elaine R. (1962 – ); WILSON, Richard K. (1959 – )
DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome.
Ley and collaborators decoded all the genes of a person with cancer (acute myeloid leukemia (AML)) and found a set of mutations that might have caused the disease or aided its progression.
GMN 13058 · https://historyofmedicine.com/id/15310
2009
Environment & Society Portal.
http://www.environmentandsociety.org/ "The Environment & Society Portal is a gateway to open access resources about human participation in, and understandings of, the environment. It addresses the community of teacher…
GMN 12058 · https://historyofmedicine.com/id/14266
2010 PÄÄBO, Svante (1955 – ); KRAUSE, Johannes (1980 – )
The complete mitochondrial DNA genome of an unknown hominin from southern Siberia.
Svante Pääbo and collaborators reconstructed the genome of the Denisova hominins and announced that they were a new species, that they interbred with our species, and that the DNA results suggest that they had dark ha…
GMN 7290 · https://historyofmedicine.com/id/9460
2010 EDWARDS, Paul N.
A vast machine: Computer models, climate data, and the politics of global warming.
GMN 7510 · https://historyofmedicine.com/id/9682
2010 SACKMAN, Douglas Cazaux (1968 – )
A companion to American environmental history. Edited by Douglas Cazaux Sackman.
GMN 9670 · https://historyofmedicine.com/id/11857
2010 CAREY, Allison F.; WANG, Guirong; CARLSON, John R.; ET AL
Odorant reception in the malaria mosquito Anopheles gambiae.
Order of authorship in the original publication: Carey, Wang, ... Carlson. The authors showed that besides CO2, the odorant receptors in the malaria mosquistoes Anopheles gambiae are sensitive to other "mostly sweat" …
GMN 11076 · https://historyofmedicine.com/id/13272
2011 FINGER, Stanley; PICCOLINO, Marco (1946 – )
The shocking history of electric fishes: From ancient epochs to the birth of modern neurophysiology.
The first comprehensive history of this subject.
GMN 6843 · https://historyofmedicine.com/id/9007
2011 CAMBRIDGE UNIVERSITY LIBRARY
Books & babies: Communicating reproduction.
http://www.lib.cam.ac.uk/exhibitions/Babies/index.html "The London underground displays posters for fertility clinics, directed at both women and men. Picture books teach children the facts of life. We are always read…
GMN 10549 · https://historyofmedicine.com/id/12742
2011 RASMUSSEN, Søren G. F.; DEVREE, Brian T.; KOBILKA, Brian Kent (1955 – ); ET AL
Crystal structure of the β2 adrenergic receptor–Gs protein complex.
Kobilka and colleagues published the crystal structure of a beta-2 receptor forming a complex with the G protein coupled receptor. This was the first time that a complete complex of an active receptor and it's Gs prot…
GMN 14134 · https://historyofmedicine.com/id/16445
2011 RASMUSSEN, Søren G. F.; KOBILKA, Brian Kent (1955 – ); CHUNG, Ka Young; ET AL
Conformational changes in the G protein Gs induced by the β2 adrenergic receptor.
Using X ray crystallographic techniques and electron microscopy, Kobilka (Nobel Prize 2012) and colleagues described the very complex nucleotide exchange and interactions at the molecular level of the alpha subunit of…
GMN 14135 · https://historyofmedicine.com/id/16446
2012 EGERTON, Frank N.
Roots of ecology: Antiquity to Haeckel.
GMN 7961 · https://historyofmedicine.com/id/10136
2012 WALLACE, Alfred Russel (1823 – 1913); VAN WYHE, John (1971 – )
Wallace online, directed by John van Wyhe.
http://wallace-online.org/ "Wallace Online is the first complete edition of the writings of naturalist Alfred Russel Wallace, including the first compilation of his specimens. The project is directed by John van Wyhe,…
GMN 8707 · https://historyofmedicine.com/id/10885
2012 GARCÍA-SANCHO, Miguel
Biology, computing and the history of molecular sequencing: From proteins to DNA, 1945-2000.
GMN 9196 · https://historyofmedicine.com/id/11377
2012 RUTKOW, Eric
American canopy: Trees, forests and the making of a nation.
GMN 9971 · https://historyofmedicine.com/id/12160
2012 DOUDNA, Jennifer Anne (1964 – ); CHARPENTIER, Emmanuelle (1968 – ); JINEK, Martin; CHYLINSKI, Krzysztof; FONFARA, Ines; HAUER, Michael
A programmable dual RNA-guided DNA endonuclease in adaptive bacterial immunity.
Order of authorship in the original publication: Jinek, Chylinski, Fonfar, Hauer, Doudna, Charpentier. Doudna, Charpentier and colleagues showed for the first time that the CRISPR evolutionary immune tool of bacteria …
GMN 11844 · https://historyofmedicine.com/id/14048
2013 ABERTH, John (1963 – )
An environmental history of the Middle Ages: The crucible of nature.
GMN 7618 · https://historyofmedicine.com/id/9790
2013 DOUDNA, Jennifer Anne (1964 – ); JINEK, Martin; CHENG, Aaron; EAST, Alexandra; ET AL
RNA-programmed genome editing in human cells.
Order of authorship in the original publication: Jinek, East, Cheng...Doudna. Doudna and colleagues presented the first demonstration that the CRISPR Cas/Cas9 bacterial editing tool functions could be applied in human…
GMN 11845 · https://historyofmedicine.com/id/14049
2013 CONG, Le; RAN, F. Ann; COX, David; ZHANG, Feng (1981 – ); ET AL
Multiplex genome engineering using CRISPR/Cas systems.
Order of authorship in the original publication: Cong, Ran, Cox....Zhang. Zhang and colleagues edited the genome of human and mouse cells (mammalian cells). Digital facsimile from PubMedCentral at this link. (Thanks t…
GMN 11846 · https://historyofmedicine.com/id/14050
2013 MALI, Prashant; YANG, Luhan; ESVELT, Kevin Michael; CHURCH, George McDonald (1954 – ); ET AL
RNA-guided human genome engineering via Cas9.
Order of authorship in the original publication: Mali, Yang, Esvelt....Church. Church and colleagues reported genome editing in human cells. Digital facsimile from PubMedCentral at this link. (Thanks to Juan Weiss for…
GMN 11847 · https://historyofmedicine.com/id/14051
2013 ADEY, Andrew C.; BURTON, Joshua N.; KLITZMAN, Jacob O.; ET AL
The haplotype-resolved genome and epigenome of the aneuploidy HeLa cancer cell line.
Adey and colleagues sequenced the haplotype-resolved whole genome of the HeLa cancer cell line. This showed a highly rearranged region at chromosome 8q24.21, where an integration locus of the HPV (human papillomavirus…
GMN 14101 · https://historyofmedicine.com/id/16412
2014 PÄÄBO, Svante (1955 – )
The complete genome sequence of a Neanderthal from the Altai Mountains.
First complete sequence of a Neanderthal genome. With more than 20 co-authors. In 2022 Pääbo was awarded the Nobel Prize in Physiology or Medicine "for his discoveries concerning the genomes of extinct hominins and hu…
GMN 7289 · https://historyofmedicine.com/id/9459
2014 ANDERSON, Eugene N. (1946 – )
Food and environment in early and medieval China.
GMN 8584 · https://historyofmedicine.com/id/10761
2014 THE INTERNATIONAL GLOSSINA GENOME INITIATIVE
Genome sequence of the Tsetse Fly (Glossina morsitans): Vector of African Tyrpanosomiasis.
The Internation Glossina Genome Initiative consisted of 179 collaborators. (Thanks to Juan Weiss for this reference and its interpretation.)
GMN 11340 · https://historyofmedicine.com/id/13538
2014 TSIAMIS, George; FALCHETTO, Marco; BRELSFOARD, Corey; ET AL
Presence of extensive Wolbachia symbiont insertions discovered in the genome of its host Glossina morsitans morsitans.
Order of authorship in the original publication: Brelsfoard, Tsiamis, Falchetto....The authors suggested that infection by Wolbachia may give a reproductive advantage to the fly that carries the parasite causing Sleep…
GMN 11341 · https://historyofmedicine.com/id/13539
2014 WILSON, Michael R.; NACCACHE, Samia N.; SAMAYOA, Erik; CHIU, Charles Y.; ET AL
Actionable diagnosis of neuroleptospirosis by next-generation sequencing.
Order of authorship in the original publication: Wilson, Naccache, Samayoa...Chiu. This research demonstrated the value of "next-generation-sequencing" in the diagnosis of a specific meningoencephalitis, a disease whi…
GMN 11397 · https://historyofmedicine.com/id/13596
2014 DOUDNA, Jennifer Anne (1964 – ); CHARPENTIER, Emmanuelle (1968 – )
The new frontier of genome engineering with CRISPR-Cas9.
Order of authorship in the original paper: Doubna, Charpenter. "Abstract "The advent of facile genome engineering using the bacterial RNA-guided CRISPR-Cas9 system in animals and plants is transforming biology. We rev…
GMN 11849 · https://historyofmedicine.com/id/14053
2014 NIU, Yuyu; SHEN, Bin; CUI, Yiqiang; ET AL
Generation of gene-modified Cynomolgus monkey via CAS9/RNA-mediated gene targeting in one-cell embryos.
Order of authorship in the original publication: Niu, Shen, Cui. The authors presented the first evidence that CRISPR can work in primates. Open Archive version available from Cell at this link. "Summary "Monkeys serv…
GMN 11863 · https://historyofmedicine.com/id/14067
2014 WLODAWER, Alexander; JASKOLSKI, Mariuz; DAUTER, Zbigniew
A brief history of macromolecular crystallography, illustrated by a family tree and its Nobel fruits.
Free access from FEBS Press at this link.
GMN 14024 · https://historyofmedicine.com/id/16331
2015 JACKSON, Myles W. (1964 – )
The genealogy of a gene: Patents, HIV/AIDS, and race.
"Myles Jackson uses the story of the CCR5 gene to investigate the interrelationships among science, technology, and society. Mapping the varied “genealogy” of CCR5—intellectual property, natural selection, Big and Sma…
GMN 11368 · https://historyofmedicine.com/id/13567
2015 BOWEN, James
The coral reef era: From discovery to decline. A history of scientific investigation from 1600 to the anthropocene epoch.
GMN 11807 · https://historyofmedicine.com/id/14009
2015 WHITWORTH, Kristin Marie; ROWLAND, Raymond R. R.; EWEN, Catherine L.; PRATHER, Randall S.; ET AL
Gene-edited pigs are protected from porcine reproductive and respiratory syndrome virus.
Order of authorship in the original publication: Whitworth, Rowland, Ewen, ... Prather. Using the CRISPR Cas molecular gene-editing tool, Prather and colleagues edited the gene that codes for the CD163 protein in adul…
GMN 11848 · https://historyofmedicine.com/id/14052
2015 LIANG, Puping; ZHANG, Xiya; XU, Yanwen; ET AL
CRISPR/Cas9-mediated gene editing in human tripronuclear zygotes.
This paper was rejected by both Nature and Science partly for "ethical objections." When published it immediately triggered worldwide controversy among scientists and the public. This was the first application of the …
GMN 11864 · https://historyofmedicine.com/id/14068
2015 GRANT, Peter Raymond (1936 – ); GRANT, Barbara Rosemary (1936 – ); LAMICHHANEY, Sangeet; BERGLUND, Jonas; ET AL
Evolution of Darwin’s finches and their beaks revealed by genome sequencing.
The authors sequenced the genome of 120 individuals representing all of Darwin’s finches. They found that a 240 kilobase haplotype encompassing the ALX1 gene, which encodes a transcription factor affecting craniofacia…
GMN 14067 · https://historyofmedicine.com/id/16378
2016 CAVERT, William M.
The smoke of London: Energy and environment in the early modern city.
GMN 8106 · https://historyofmedicine.com/id/10282
2016
Data Refuge.
https://www.datarefuge.org/ "Data Refuge is a public and collaborative project designed to address concerns about federal climate and environmental data that is in danger of being lost[1]. In particular, the initiativ…
GMN 9594 · https://historyofmedicine.com/id/11781
2016 POWELL, Miles A.
Vanishing America: Species extinction racial peril, and the origins of conservation.
"Nineteenth-century citizens of European descent widely believed that Native Americans would eventually vanish from the continent. Indian society was thought to be tied to the wilderness, and the manifest destiny of U…
GMN 10421 · https://historyofmedicine.com/id/12614
2016 GRANDE, Laura; MICHELACCI, Valeria; BONDI, Roslen; ET AL
Whole-genome characterization and strain comparison of VT2f-producing Escherichia coli causing hemolytic uremic syndrome.
Order of authorship in the original publication: Grande, Michelacci, Bondi.... Demonstration that a phage infecting E. coli conveys the genes into the E. coli that code for the production of the verotoxin that causes …
GMN 11409 · https://historyofmedicine.com/id/13608
2017 GRUBAUGH, Nathan D.; LADNER, Jason T.; KRAEMER, Moritz U.G.; ET AL
Genomic epidemiology reveals multiple introductions of Zika virus into the United States.
Order of authorship in the original publication: Grubaugh, Ladner, Kraemer. The authors found that the Zika virus was introduced into Florida at least 4 times, but perhaps as many as 40 times, before it was detected, …
GMN 10945 · https://historyofmedicine.com/id/13141
2017 GAUDELLI, Nicole M.; KOMOR, Alexis C.; REES, Holly; LIU, David Ruchien (1973 – ); ET AL
Programmable base editing of A-T to G-C.
Order of authorship in the original publication: Gaudelli, Komor, Rees....Liu. Liu and colleagues developed an advanced CRISPR system that can edit pairings of DNA nucleotide bases Adenine and Thymine into Guanine and…
GMN 11865 · https://historyofmedicine.com/id/14069
2017 HAYFLICK, Leonard (1928 – 2024); OLSHANSKY, Stuart Jay (1954 – )
The role of the WI-38 cell strain in saving lives and reducing morbidity.
In 1961 "Hayflick developed the first normal human diploid cell strains for studies on human aging and for research use throughout the world. Prior to his seminal research, all cultured cell lines were immortal and an…
GMN 14102 · https://historyofmedicine.com/id/16413
