1881 GALTIER, Pierre-Victor (1846 – 1908)
Les injections de virus rabique dans le torrent circulatoire ne provoquent pas l’éclosion de la rage et semblant conférer l’immunité. La rage peut être transmise par l’ingestion de la matiére rabique.
Galtier immunized sheep by inoculating rabid saliva in the veins; this did not produce the disease and protected the animals from a further inoculation. His work aroused the interest of Pasteur.
GMN 5481.3 · https://historyofmedicine.com/id/6378
1881 PASTEUR, Louis (1822 – 1895); CHAMBERLAND, Charles (1851 – 1908); ROUX, Pierre Paul Émile (1853 – 1933); THUILLIER, Louis (1856 – 1883)
Sur la rage.
This paper marks the beginning of Pasteur’s studies on rabies. English translation in R. Suzor, Hydrophobia: An account of M. Pasteur’s system…London, 1887.
GMN 5481.4 · https://historyofmedicine.com/id/6382
1884 PASTEUR, Louis (1822 – 1895); CHAMBERLAND, Charles (1851 – 1908); ROUX, Pierre Paul Émile (1853 – 1933)
Nouvelle communication sur la rage.
Demonstration in the blood of the rabies virus. English translation in R. Suzor, Hydrophobia: An account of M. Pasteur’s system…London, 1887.
GMN 5482 · https://historyofmedicine.com/id/6383
1885 PASTEUR, Louis (1822 – 1895)
Méthode pour prévenir la rage après morsure.
Pasteur’s papers describing his rabies vaccine, and the results he attained with it gave further proof of the value of attenuated virus as a protective inoculum against infective diseases in man and animals. This is c…
GMN 2541 · https://historyofmedicine.com/id/3549
1903 NEGRI, Adelchi (1876 – 1912)
Contributo alio studio dell’ eziologia della rabia.
Discovery of the “Negri bodies” in rabies, the size of which makes viewing possible with a light microscope, and allows prompt microscopic diagnosis. German translation in Z. Hyg. InfektKr., 1903, 43, 507-28. Even tho…
GMN 5484 · https://historyofmedicine.com/id/6388
1903 REMLINGER, Paul (1871 – 1964)
Le passage du virus rabique à travers les filtres.
By demonstrating that the rabies organism is filterable Remlinger proved that rabies is a virus. The rabies virus was the second virus causing disease in humans to be identified. Remlinger made his discovery by follow…
GMN 14034 · https://historyofmedicine.com/id/16341
1908 FERMI, Claudio (1862 – 1952)
Über die Immunisierung gegen Wutkrankheit.
Fermi was the first to use chemical treatment of tissue suspensions of fixed rabies virus for the preparation of vaccine (Fermi vaccine). He introduced the use of carbolic acid for this purpose.
GMN 5484.1 · https://historyofmedicine.com/id/6389
1936 WEBSTER, Leslie Tillotson (1894 – 1943); CLOW, Anna D. (1905 – 1992)
Propagation of rabies virus in tissue culture and the successful use of culture virus as antirabic vaccine.
Webster and Clow succeeded in growing rabies virus in tissue culture.
GMN 5484.2 · https://historyofmedicine.com/id/6390
1939 DAWSON, James Robertson Jr. (1908 – 1986)
Infection of chicks and chick embryos with rabies.
Cultivation of rabies virus in the chick embryo. Soon afterwards I. J. Kligler and H. Bernkopf, Nature, 1939, 143, 899, made a similar report.
GMN 5484.3 · https://historyofmedicine.com/id/6391
1965 MIYAMOTO, Kaneatsu; MATSUMOTO, Seiichi
The nature of the Negri Body.
The first visual proof, by publication of electron micrographs at 25,000 magnification, that Negri bodies contain enormous numbers of rabies virus particles. Digital facsimile from rupress.org at this link. (Thanks to…
GMN 14035 · https://historyofmedicine.com/id/16343
1973 WIKTOR, Tadeusz Jan (1921 – 1986)
Human cell culture rabies vaccine. Antibody response in man.
Human diploid cell vaccine. With S. A. Plotkin and D. W. Grella. See also Develop, biol. Standard., 1978, 40, 3-9.
GMN 5484.4 · https://historyofmedicine.com/id/6393
