1965 BLUMBERG, Baruch Samuel (1925 – 2011); ALTER, Harvey James (1935 – ); VISNICH, S.; ET AL

A “new” antigen in leukemia sera.

(Order of authorship in the original publication: Blumberg, Alter, Visnich.) Discovery of Australia antigen, hepatitis B antigen, Aa, later called HBsAg. Blumberg received half of the Nobel Prize for Medicine in Biolo…

GMN 3666.4 · https://historyofmedicine.com/id/4823

1968 BLUMBERG, Baruch Samuel (1925 – 2011); BAYER, Manfred E. (1928 – 2015); WERNER, Barbara G.

Particles associated with Australia antigen in the sera of patients with leukemia, Down's syndrome and hepatitis.

Particles with the appearance of a virus were detected by electron microscopy in the serum of individuals with Au. These were subsequently shown to be the surface antigen particles, different from the whole virus part…

GMN 6840 · https://historyofmedicine.com/id/9004

1969 –1972 BLUMBERG, Baruch Samuel (1925 – 2011); MILLMAN, Irving (1923 – 2012)

Vaccine against viral hepatitis and process. Serial No. 864,788 filed 10 /8 /[19]69. Patent 3636191 issued 1/ 18/ [19]72.

First description of the hepatitis B vaccine, the first cancer vaccine, US patent 3636191A. Millman and Blumberg discovered that the blood of individuals carrying the hepatitis B virus contained particles of the outsi…

GMN 6841 · https://historyofmedicine.com/id/9005

1970 SHERLOCK, Sheila Patricia Violet Dame (1918 – 2001); NIAZI, S. P.; FOX, R. A.

Chronic liver disease and primary liver-cell cancer with hepatitis-associated (Australia) antigen in serum.

(Order of authorship in the original publication: Sherlock, Niazi, Fox...). The authors demonstrated that the hepatitis B virus can cause cancer. (Thanks to Juan Weiss for this reference and its interpretation.)

GMN 12306 · https://historyofmedicine.com/id/14528

1970 BLUMBERG, Baruch Samuel (1925 – 2011); MILLMAN, Irving (1923 – 2012); BAYER, Manfred E. (1928 – 2015); LOEB, Lawrence A.

Australia antigen (a hepatitis-associated antigen). Purification and physical properties.

Purification of the Australia antigen and investigation of its physical properties. (Order of authorship in the original publication: Millman, Loeb, Bayer, Blumberg.) Blumberg shared the 1976 Nobel Prize in Physiology…

GMN 12321 · https://historyofmedicine.com/id/14544