1843 BARLOW, George Hilaro (1806 – 1866); REES, George Owen (1813 – 1889)
Account of observations… on patients whose urine was albuminous.
An early description of a case of subacute bacterial endocarditis is reported on pp. 227-32 (Case 8).
GMN 2753 · https://historyofmedicine.com/id/4645
1869 WINGE, Emanuel Fredrik Hagbarth (1827 – 1894)
Mycosis endocardii.
Winge first suggested that endocarditis was due to microbial infection. A translation of part of his paper is in Major, Classic descriptions of disease, 3rd ed., 1945, p. 472.
GMN 2767 · https://historyofmedicine.com/id/4700
1870 WILKS, Sir Samuel (1824 – 1911)
Capillary embolism or arterial pyaemia.
One of the first accounts of bacterial endocarditis was given by Wilks, who, in his classic paper on the subject, called the condition “arterial pyaemia.” Reprinted in Willius & Keys, Cardiac classics, 1941, pp. 579-84.
GMN 2769 · https://historyofmedicine.com/id/4702
1872 HEIBERG, Hjalmar (1837 – 1897)
Ein Fall von Endocarditis ulcerosa puerperalis mit Pilzbildungen im Herzen (Mycosis endocardii).
Heiberg suggested the microbic nature of endocarditis. He described what appeared to him to be the mycelia of Leptothrix in the vegetations of a case of ulcerative endocarditis.
GMN 2774 · https://historyofmedicine.com/id/4719
1878 KLEBS, Theodor Albrecht Edwin (1834 – 1913)
Weitere Beiträge zur Entstehungsgeschichte der Endocarditis.
Klebs "concluded that most cases of acute endocarditis were caused by 'monads' or by 'septic cocci' " (Bloomfield, Bibliography of internal medicine, selected diseases, 43-44). Klebs believed that all cases of endocar…
GMN 12257 · https://historyofmedicine.com/id/14473
1885 OSLER, Sir William (1849 – 1919)
The Gulstonian Lectures, on malignant endocarditis.
First comprehensive description of subacute bacterial endocarditis.
GMN 2790 · https://historyofmedicine.com/id/3396
1896 THAYER, William Sydney (1864 – 1932); BLUMER, George Alder (1857 – 1940)
Ulcerative endocarditis due to the gonococcus; gonorrheal septicemia.
Thayer and Blumer found the gonococcus in cases of gonorrheal endocarditis.
GMN 5212 · https://historyofmedicine.com/id/7812
1908 –1909 OSLER, Sir William (1849 – 1919)
Chronic infectious endocarditis.
The tender subcutaneous nodes in subacute bacterial endocarditis (“Osler’s nodes”) were first observed by Osler in 1888, and reported in 1909. This paper is the first definite clinical description of subacute bacteria…
GMN 2827 · https://historyofmedicine.com/id/3538
1909 BRACHT, Erich Frans Eugen (1882 – 1969); WÄCHTER, Hermann Julius Gustav (1878 – 1944)
Beitrag zur Aetiologie und pathologischen Anatomie der Myokarditis rheumatica.
“Bracht–Wächter bodies” in the myocardium in bacterial endocarditis.
GMN 2828 · https://historyofmedicine.com/id/3543
1909 HORDER, Thomas Jeeves (1871 – 1955)
Infective endocarditis, with an analysis of 150 cases.
Classic description of subacute bacterial endocarditis.
GMN 2829 · https://historyofmedicine.com/id/3546
1910 LIBMAN, Emanuel (1872 – 1946); CELLER, Herbert Louis (1878 – 1928)
The etiology of subacute infective endocarditis.
Libman and Celler found Strep. endocarditis to be the most common cause of subacute bacterial endocarditis.
GMN 2834 · https://historyofmedicine.com/id/3560
1910 SCHOTTMÜLLER, Hugo (1867 – 1936)
Endocarditis lenta. Zugleich ein Beitrag zur Artunterscheidung der pathogenen Streptokokken.
First to isolate Strep viridans in cases of bacterial endocarditis, Schottmüller named the condition Endocarditis lenta.
GMN 2836 · https://historyofmedicine.com/id/3569
1912 LIBMAN, Emanuel (1872 – 1946)
A study of the endocardial lesions of subacute bacterial endocarditis.
GMN 2841 · https://historyofmedicine.com/id/3589
1924 LIBMAN, Emanuel (1872 – 1946); SACKS, Benjamin (1896 – 1939)
A hitherto undescribed form of valvular and mural endocarditis.
“Libman–Sacks disease”.
GMN 2855 · https://historyofmedicine.com/id/3645
1948 CHRISTIE, Ronald Victor (1902 – 1986)
Penicillin in subacute bacterial endocarditis. Report to the Medical Research Council on 269 patients treated in 14 centres appointed by the Penicillin Clinical Trials Committee.
GMN 2880 · https://historyofmedicine.com/id/4224
