1990 KING, Mary-Claire (1946 – )

Linkage of early-onset familial breast cancer to Chromosome 17q21.

King showed that breast cancer can be inherited due to mutations in the Breast cancer type 1 susceptibility protein, a protein that in humans is encoded by the BRAC1 gene. BRCA1 is a human tumor suppressor gene (also …

GMN 13966 · https://historyofmedicine.com/id/16268

1994 SKOLNICK, Mark Henry (1946 – ); MIKI, Yoshio; SHATTUCK-EIDENS, Donna; ET AL

A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1.

Discovery of the BRCA1 gene using the technique of restriction fragment length polymorphism (RFLP). (Thanks to Juan Weiss for this reference and its interpretation.)

GMN 14015 · https://historyofmedicine.com/id/16322

1994 STRATTON, Sir Michael Rudolf (1957 – ); WOOSTER, Richard; NEUHAUSEN, Susan L.; MANGION, Jonathan; ET AL

Location of a breast cancer susceptibility gene, BRACA2, to chromosome 13q12-13.

Stratton and colleagues discovered the BRCA2 gene. Oder of authorship in the original publication: Wooster, Neuhausen, Mangion....Stratton. (Thanks to Juan Weiss for this reference and its interpretation.)

GMN 14016 · https://historyofmedicine.com/id/16323