1527 MASSA, Niccoló (1489 – 1569)
Liber de morbo gallico.
Includes a description of the neurological manifestations of syphilis. Though this work bears the date 1507, Peter Krivatsy, provided evidence that this edition was printed in 1527. See Krivatsy, "Nicola Massa's Liber…
GMN 2365 · https://historyofmedicine.com/id/3200
1817 LOEWENHARDT, Sigismund Eduard (1796 – 1875)
De myelophthisi chronica vera et notha.
First important account of tabes dorsalis.
GMN 4772 · https://historyofmedicine.com/id/1442
1827 HORN, Wilhelm von (1803 – 1871)
De tabe dorsuali praelusio.
Gives the views of his father, Ernst Horn (1744-1848), on tabes.
GMN 4773 · https://historyofmedicine.com/id/1458
1858 –1859 DUCHENNE DE BOULOGNE, Guillaume Benjamin Armand (1806 – 1875)
De l’ataxie locomotrice progressive.
Although far from being the first to describe tabes dorsalis, Duchenne gave a classic account of the condition, earning the eponym “Duchenne’s disease”.
GMN 4774 · https://historyofmedicine.com/id/1467
1866 CHARCOT, Jean Martin (1825 – 1893); BOUCHARD, Abel (1833 – 1899)
Douleurs fulgurantes de l’ataxie sans incoordination des mouvements; sclérose commençante des cordons postérieurs de la moëlle épinière.
First clinical description of the electric pains in tabes.
GMN 4775 · https://historyofmedicine.com/id/1474
1866 DELAMARRE, Georges
Des troubles gastriques dans l’ataxie locomotrice progressive. Thèse pour le doctorat en médecine. No. 250.
Tabetic gastric crises first described. Digital facsimile from the Internet Archive at this link.
GMN 4776 · https://historyofmedicine.com/id/1480
1868 CHARCOT, Jean Martin (1825 – 1893)
Sur quelques arthropathies qui paraissent dépendre d’une lésion du cerveau ou de la moëlle épinière.
Charcot called attention to tabetic arthropathy, a condition which has since borne his name, while the tabetic joints he so well described are now known as “Charcot’s joints”.
GMN 4337 · https://historyofmedicine.com/id/1488
1868 ALLBUTT, Sir Thomas Clifford (1836 – 1925)
Case of cerebral disease in a syphilitic patient.
Syphilitic endarteritis of cerebral arteries described.
GMN 4778 · https://historyofmedicine.com/id/1496
1869 ALLBUTT, Sir Thomas Clifford (1836 – 1925)
Remarks on a case of locomotor ataxy with hydrarthrosis.
An early description of the joint symptoms in tabes dorsalis.
GMN 4779 · https://historyofmedicine.com/id/1506
1875 ERB, Wilhelm Heinrich (1840 – 1921)
Ueber Sehnenreflexe bei Gesunden und bei Rückenmarkskranken.
Knee-jerk first used as diagnostic measure in tabes dorsalis.
GMN 4780 · https://historyofmedicine.com/id/1511
1875 WESTPHAL, Carl Friedrich Otto (1833 – 1890)
Ueber einige durch mechanische Einwirkung auf Sehnen und Muskeln hervorgebrachte Bewegungs-Erscheinungen.
Westphal discovered the diagnostic value of the knee-jerk simultaneously with Erb.
GMN 4781 · https://historyofmedicine.com/id/1513
1877 CLOUSTON, Sir Thomas Smith (1841 – 1915)
A case of general paralysis at the age of sixteen.
Clouston, eminent English psychiatrist, was the first definitely to recognize the relationship between paresis and congenital syphilis and to report a case. This paper is also of interest as being the only recorded ca…
GMN 4799 · https://historyofmedicine.com/id/1556
1882 FOURNIER, Jean Alfred (1832 – 1915)
De l’ataxie locomotrice d’origine syphilitique.
Fournier advanced the doctrine of the syphilitic origin of tabes, a hypothesis which was opposed for a time.
GMN 4782 · https://historyofmedicine.com/id/1515
1884 LEICHTENSTERN, Otto Michael Ludwig (1845 – 1900)
Ueber progressive perniciöse Anämie bei Tabeskranken
First description of subacute combined degeneration of the spinal cord, which Leichtenstern termed progressive pernicious anemia in tabetics.
GMN 3128 · https://historyofmedicine.com/id/3922
1887 DEJERINE, Joseph Jules (1849 – 1917)
Sur un cas de paraplégie par névrites périphériques, chez un ataxique morphiomane.
First description of peripheral neuritis, “Dejerine’s neurotabes”.
GMN 4784 · https://historyofmedicine.com/id/1517
1889 DEJERINE, Joseph Jules (1849 – 1917)
Sur l’atrophie musculaire des ataxiques.
Dejerine ranks high in French neurology. He became clinical chief at the Salpêtrière. He separated peripheral from medullary tabes, wrote on the tabetic muscular atrophies, on the parietal lobe syndrome, and made many…
GMN 4785 · https://historyofmedicine.com/id/1519
1890 FRENKEL, Heinrich (1860 – 1931)
Die Therapie atactischer Bewegungsstörungen.
Frenkel devised certain muscular exercises for use in the treatment of tabes dorsalis.
GMN 4786 · https://historyofmedicine.com/id/1521
1892 ERB, Wilhelm Heinrich (1840 – 1921)
Ueber syphilitische Spinalparalyse.
Erb’s classic description of syphilitic spinal paralysis, sometimes called “Erb’s disease”.
GMN 4788 · https://historyofmedicine.com/id/1525
1892 ERB, Wilhelm Heinrich (1840 – 1921)
Die Aetiologieder Tabes.
English translation, 1900.
GMN 4789 · https://historyofmedicine.com/id/1526
1894 FOURNIER, Jean Alfred (1832 – 1915)
Les affections parasyphilitiques.
Fournier, great French venereologist, introduced the concept of “parasyphilis”. He showed statistically the causal relationship of syphilis to paresis and tabes.
GMN 4800 · https://historyofmedicine.com/id/1559
1898 PEL, Pieter Klazes (1852 – 1919)
Augenkrisen bei Tabes dorsalis.
“Pel’s crises” – the ocular crises in tabes.
GMN 4791 · https://historyofmedicine.com/id/1530
1899 RAECKE, Julius (1872 – 1930)
Paralyse und Tabes bei Eheleuten. Ein Beitrag zur Aetiologie beider Krankheiten.
GMN 4801 · https://historyofmedicine.com/id/1563
1902 NONNE, Max (1861 – 1959)
Syphilis und Nervensystem.
GMN 4792 · https://historyofmedicine.com/id/1533
1906 WASSERMANN, August von (1866 – 1925); PLAUT, Felix (1877 – 1940)
Ueber das Vorhandensein syphilitischer Antistoffe in der Cerebrospinalflüssigkeit von Paralytikem.
Wassermann applied his test (No. 2402) to the cerebrospinal fluid and, in paretics, obtained positive results in over 90 per cent of cases. The test greatly facilitated the diagnosis of general paralysis.
GMN 4804 · https://historyofmedicine.com/id/1573
1909 FOERSTER, Otfrid (1873 – 1941); KÜTTNER, Hermann (1870 – 1932)
Ueber operative Behandlung gastrischer Krisen durch Resektion der 7-10. hinteren Dorsalwurzel.
Foerster’s operation for tabes.
GMN 4881 · https://historyofmedicine.com/id/5772
1913 NOGUCHI, Hideyo (1876 – 1928); MOORE, Joseph Waldron (1879 – )
A demonstration of Treponema pallidum in the brain in cases of general paralysis.
A pure culture of Trep. pallidum was obtained from a case of dementia paralytica.
GMN 4805 · https://historyofmedicine.com/id/1575
1913 LANGE, Karl Friedrich August (1883 – )
Die Ausflockung kolloidalen Goldes durch Zerebrospinalflüssigkeit bei luetischenAffektiondesZentralnervensystems.
Lange’s colloidal gold test for the diagnosis of cerebrospinal syphilis. See also Berl. klin. Wschr., 1912, 49, 897-901.
GMN 2406 · https://historyofmedicine.com/id/3374
