1982 PRUSINER, Stanley Benjamin (1942 – )

Novel proteinaceous infectious particles cause Scrapie.

In 1997 Prusiner was awarded the Nobel Prize in Physiology or Medicine "for his discovery of Prions - a new biological principle of infection." In his 1982 paper Prusiner proposed a completely novel explanation for th…

GMN 10140 · https://historyofmedicine.com/id/12329

1982 GAJDUSEK, Daniel Carleton (1923 – 2008); MASTERS, Colin Louis (1947 – )

The spectrum of Creutzfeldt-Jakob disease and the virus-induced subacute spongiform encephalopathies. IN: Smith & Cavanagh, editors, Recent advances in neuropathology, Vol. 2., Chapter 6, pp. 129-163.

The authors reported a detailed and complete analysis of the original slides of the brain done by Afons Jakob, and provided a partial translation into English, with a detailed analysis of Jakob's clinical description,…

GMN 12595 · https://historyofmedicine.com/id/14835

1987 HACHINSKI, Vladimir (1941 – ); STEINGART, Allan; MERSKEY, Harold (1929 – ); ET AL

Cognitive and neurologic findings in subjects with diffuse white matter lucencies on computed tomographic scan (Leuko-Araiosis).

"Abstract: As part of a prospective clinicopathologic study, a cohort of 105 "normal" elderly volunteers was investigated with computed tomographic scans, psychometric testing (Extended Scale for Dementia [ESD]) and n…

GMN 14116 · https://historyofmedicine.com/id/16427

1996 WILL, R. G.; IRONSIDE, J. W.; ZEIDLER, M.; ET AL

A new variant of Creutzfeldt-Jakob disease in the UK.

During the 1990s England was plagued with cases of Bovine Spongiform Encephalopathy (BSE) seen in cows, popularly known as "Mad Cow Disease." Then physicians in England started noticing an uptick in cases of what look…

GMN 10844 · https://historyofmedicine.com/id/13040

2005 MURRAY, Thomas John "Jock" (1938 – )

Multiple sclerosis: The history of a disease.

GMN 8729 · https://historyofmedicine.com/id/10907

2014 PRUSINER, Stanley Benjamin (1942 – )

Madness and memory: The discovery of prions- a new biological principle of disease.

Prusiner discovered prions, the agent causing scrapie in sheep and goats, mad cow disease, and Creutzfeldt-Jakob disease in humans.

GMN 7624 · https://historyofmedicine.com/id/9796