1927 COOLEY, Thomas Benton (1871 – 1945); ET AL

Anemia in children, with splenomegaly and peculiar changes in the bones.

“Cooley’s erythroblastic anemia”, thalassemia. With E. R. Witwer and O. P. Lee. An earlier brief account by Cooley and Lee appeared in Trans. Amer. Pediat. Soc.,1925, 37, 29.

GMN 3141 · https://historyofmedicine.com/id/3951

1936 WHIPPLE, George Hoyt (1878 – 1976); BRADFORD, William Leslie (1898 – 1983)

Mediterranean disease – thalassemia (erythroblastic anemia of Cooley); associated pigment abnormalities simulating hemochromatosis.

Whipple and Bradford contributed a classic paper on the pathology of thalassemia, a name introduced by them.

GMN 3148.1 · https://historyofmedicine.com/id/3991

1938 CAMINOPETROS, J

Recherches sur l’anémie érythroblastique infantile des peuples de la Méditerranée orientale. Étude anthropologique, étiologique et pathogénique. La transmission héréditaire de la maladie.

First evidence that thalassemia is genetically determined. Earlier report in Kliniki, Athens, 1936, 12, No. 5.

GMN 3148.2 · https://historyofmedicine.com/id/3993

1959 INGRAM, Vernon Martin (1924 – 2006); STRETTON, Antony Oliver Ward (1936 – )

Genetic basis of the thalassaemia diseases.

GMN 3155.2 · https://historyofmedicine.com/id/4056

2021 FRANGOUL, Haydar A.; ALTSHULER, David Matthew (1964 – ); CAPPELLINI, Maria Domenica; ET AL

CRISPR-Cas9 gene editing for sickle cell disease and ß-thalassemia.

First application of CRISPR gene editing in the successful cure of diseases. Order of authorship in the original publication: Frangoul, Altshuler, Cappellini. (Thanks to Juan Weiss for this reference and its interpret…

GMN 13478 · https://historyofmedicine.com/id/15752