1817 PARKINSON, James (1755 – 1824)
An essay on the shaking palsy.
“Parkinson’s disease”–paralysis agitans. Reprinted in Med. Classics, 1938, 2, 946-97. Facsimile edition, with biography of Parkinson by Macdonald Critchley, London, 1955. Digital facsimile from the Internet Archive at…
GMN 4690 · https://historyofmedicine.com/id/972
1868 ORDENSTEIN, Leopold (1835 – 1902)
Sur la paralysie agitante et la sclérose en plaques généralisée.
In his doctoral thesis Ordenstein, a pupil of Charcot, first defined the clinical features of multiple schlerosis in detail, with pathologic confirmation, and distinguished the main symptoms and pathologic findings of…
GMN 13813 · https://historyofmedicine.com/id/16102
1920 FOIX, Charles (1882 – 1927)
Les lésions anatomiques de la maladie de Parkinson.
Foix and his colleagues showed that the specific lesion in Parkinson’s disease is in the substantia nigra of the mid-brain.
GMN 4721 · https://historyofmedicine.com/id/1218
1921 SOUQUES, Achille Alexandre (1860 – 1944)
Rapport sur les syndromes parkinsoniens.
Souques recognized the importance of encephalitis lethargica as a cause of Parkinsonism; more than any other neurologist he was responsible for unifying its diverse manifestations.
GMN 4723 · https://historyofmedicine.com/id/1225
1946 GRÜNTHAL, Ernst (1894 – 1972)
Ueber Parpanit, einen neuen estrapyramidal-motorische Störungen beeinflussenden Stoff.
Introduction of caramiphen (“parpanit”) in the treatment of Parkinson’s disease.
GMN 4726 · https://historyofmedicine.com/id/1240
1946 SIGWALD, Jean (1903 – ); ET AL
Le traitement de la maladie de Parkinson par le chlorhydrate de diéthylaminoéthyl-N-thiodiphénylamine (2987 R.P.). Premiers résultats.
Introduction of “diparcol” in the treatment of Parkinson’s disease. With D. Boyet and G. Dumont.
GMN 4727 · https://historyofmedicine.com/id/1242
1949 SIGWALD, Jean (1903 – )
Un nouveau médicament symptomatique des syndromes parkinsoniens: le chlorhydrate de [(diéthylamino-2’-methyl-2’) éthyl-1-’] N-dibenzoparathiazine.
Introduction of ethopropazine (“lysivane”) in the treatment of Parkinson’s disease.
GMN 4728 · https://historyofmedicine.com/id/1244
1949 CORBIN, Kendall Brooks (1907 – 1999)
Trihexyphenidyl. Evaluation of the new agent in the treatment of parkinsonism.
Clinical introduction of benzhexol (“artane”) in Parkinson’s disease.
GMN 4729 · https://historyofmedicine.com/id/1247
