1810 WOLLASTON, William Hyde (1766 – 1828)

On cystic oxide, a new species of urinary calculus.

Cystine, the first amino-acid to be isolated, was prepared by Wollaston from a urinary calculus. This was also the first report of cystinuria.

GMN 668.1 · https://historyofmedicine.com/id/622

1846 –1848 GARROD, Sir Alfred Baring (1819 – 1907)

Several specimens of cystine exhibited, with the particulars of two cases in which this deposit occurred in the urine.

Cystinuria described.

GMN 3912.1 · https://historyofmedicine.com/id/5016

1909 GARROD, Sir Archibald Edward (1857 – 1936)

Inborn errors of metabolism.

Garrod established chemical individuality as a paradigm of Mendelian variation. His study, which he began around the turn of the 20th century, coincided with the rediscovery of Mendel's laws of inheritance in 1900. He…

GMN 244.1 · https://historyofmedicine.com/id/5049