1822 BAYLE, Antoine Laurent Jessé (1799 – 1858)

Recherches sur l’arachnitis chronique, la gastrite et la gastro-entérite chroniques, et la goutte: Considerées comme causes de l'aliénation mentale. Thèse No. 247.

First description of general paresis, or paralytic dementia, general paralysis of the insane, or "maladie de Bayle". This is considered the first demonstation of an organic cause for a "psychiatric" disorder; it was i…

GMN 4795 · https://historyofmedicine.com/id/1545

1826 CALMEIL, Louis-Florentin (1798 – 1895)

De la paralysie consideree chez les aliénés.

Classic description of general paralysis. Calmeil’s work complements Bayle’s earlier delineation of general paralysis (No. 4795). Between the two of them they established the clinical picture of general paralysis of t…

GMN 4797 · https://historyofmedicine.com/id/1552

1838 ESQUIROL, Jean Étienne Dominique (1772 – 1840)

Des maladies mentales. 2 vols. and atlas.

Esquirol succeeded Pinel at the Salpêtrière, and was the first lecturer on psychiatry. After Pinel he was a founder of the French School. This is the first modern textbook on psychiatry. It is notable for its striking…

GMN 4798 · https://historyofmedicine.com/id/6144

1877 CLOUSTON, Sir Thomas Smith (1841 – 1915)

A case of general paralysis at the age of sixteen.

Clouston, eminent English psychiatrist, was the first definitely to recognize the relationship between paresis and congenital syphilis and to report a case. This paper is also of interest as being the only recorded ca…

GMN 4799 · https://historyofmedicine.com/id/1556