1952 MÜLLER, J. M.; ET AL
Reserpin, der sedative Wirkstoff aus Rauwolfia serpentina Benth.
Isolation of reserpine. With E. Schlittler and H. J. Bein.
GMN 1931 · https://historyofmedicine.com/id/2750
1952 MCGUIRE, James Myrlin (1909 – ); ET AL
“Ilotycin”, a new antibiotic.
Discovery of erythromycin. With R. L. Bunch, R. C. Anderson, H. E. Boaz, E. H. Flynn, H. M. Powell, and J. W. Smith.
GMN 1946 · https://historyofmedicine.com/id/2812
1952 ROBITZEK, Edward Heinrich (1912 – 1984); ET AL
Chemotherapy of human tuberculosis with hydrazine derivatives of isonicotinic acid. (Preliminary report of representative cases.)
Introduction of isoniazid. With I. J. Selikoff and G. G. Omstein. See also Amer. Rev. Tuberc., 1952, 65, 257-442.
GMN 2353 · https://historyofmedicine.com/id/3139
1952 LEDERBERG, Joshua (1925 – 2008); LEDERBERG, Esther (1922 – 2006)
Replica plating and indirect selection of bacterial mutants.
Demonstration of the mutational basis of antibiotic resistance. Digital facsimile from PubMedCentral at this link.
GMN 9719 · https://historyofmedicine.com/id/11906
1952 FLOREY, Lady Mary Ethel (1900 – 1966)
The clinical application of antibiotics. Penicillin.
Printed on the title page: "This volume, although a separate publication, is a continuation of the work described in Antibiotics Volumes I and II, and may be read in conjunction with it." (Thanks to Juan Weiss for thi…
GMN 12615 · https://historyofmedicine.com/id/14855
1953 CHANG, Min Chueh (1908 – 1991); PINCUS, Gregory Goodwin (1903 – 1967)
The effects of progesterone and related compounds on ovulation and early development in the rabbit.
First practical demonstration of an oral contraceptive.
GMN 1931.2 · https://historyofmedicine.com/id/2754
1953 –1959 LAGUNA DE SEGOVIA, Andrés [LACUNA] (1499 – 1559); DIOSCORIDES, Pedanius [Πεδάνιος Διοσκουρίδης] (40 – 90); DUBLER, César E. (1915 – 1966)
La "Materia médica" de Dioscórides: Transmisión medieval y renacentista by César E. Dubler. Vol. I: La transmisión medieval y renacentista y la supervivencia en la medicina popular moderna de la "Materia médica" de Dioscórides, estudiada particularmente en España y África del Norte. Vol. 2: La versión árabe de la 'Materia Médica' de Dioscórides (texto, variantes e indices): estudio de la transcripción de los nombres griegos al árabe y comparación de las versiones griega, árabe y castellana. Vol. 3: La "Materia médica" de Dioscórides traducida y comentada por D. Andrés de Laguna (Texto crítico). Vol. 4: D. Andrés de Laguna y su época. Vol. 5: Glosario médico castellano del siglo XVI. Prólogo de Gregorio Marañón. Vol. 6: Indices generales y léxico especial de Andrés de Laguna.
GMN 9245 · https://historyofmedicine.com/id/11427
1954 ABRAHAM, Sir Edward Penley (1913 – 1999); ET AL
Purification and some properties of cephalosporin N, a new penicillin.
With G. G. F. Newton and C. W. Hale.
GMN 1947 · https://historyofmedicine.com/id/2813
1954 DJERASSI, Carl (1923 – 2015); MIRAMONTES CARDÉNAS, Luis Ernesto (1925 – 2004); ROSENKRANZ, George (1916 – ); SONDHEIMER, Franz (1926 – 1981)
Steroids. LIV.Synthesis of 19-Nov-17α-ethynyltestosterone and 19-Nor-17α-methyltestosterone.
Synthesis of Norethisterone (or norethindrone) (or 19-nor-17α-ethynyltestosterone), the first highly active progestin analog that was effective when taken by mouth. This molecule became part of one of the first succes…
GMN 7085 · https://historyofmedicine.com/id/9252
1955 ABRAHAM, Sir Edward Penley (1913 – 1999); NEWTON, Guy G. F. (1920 – 1969)
Cephalosporin C, a new antibiotic containing sulpher and d-x aminoadipic acid.
GMN 1947.1 · https://historyofmedicine.com/id/2814
1955 –1956 GOLD, W; ET AL
Amphotericins A and B, antifungal antibiotics produced by a streptomycete.
With six co-authors.
GMN 1947.2 · https://historyofmedicine.com/id/2815
1955 FARBER, Sidney (1903 – 1973)
Carcinolytic action of antibiotics: puromycin and actinomycin.
GMN 2660.8 · https://historyofmedicine.com/id/3389
1955 FRAENKEL-CONRAT, Heinz Ludwig (1910 – 1999); WILLIAMS, Robley Cook (1908 – 1995)
Reconstitution of active tobacco mosaic virus from its inactive protein and nucleic acid components.
First reconstitution of a virus.
GMN 2527 · https://historyofmedicine.com/id/3465
1955 MCGUIRE, James Myrlin (1909 – ); MCCORMICK, M. H.; PITTENGER, G. E.
Vancomycin, a new antibiotic. I. Chemical and biologic properties.
Edmund Kornfeld, an organic chemist working at Eli Lilly, first isolated Vancomycin in 1953 from a soil sample collected from the interior jungles of Borneo by a missionary, Rev. William M. Bouw (1918-2006). The organ…
GMN 11468 · https://historyofmedicine.com/id/13667
1956 HATA, Toju (1908 – 2004); ET AL
Mitomycin, a new antibiotic from streptomyces.
Isolation of mitomycin C, effective in Hodgkin’s disease and lymphoma. With six co-authors.
GMN 1947.3 · https://historyofmedicine.com/id/2817
1956 DAVEY, Thomas Frank (1908 – 1983); CURRIE, Gordon
Clinical trials of diphenyl thiourea compound SU 1906 (Ciba 1509E) in the treatment of leprosy. Progress during the first year.
Introduction of diphenylthiourea (thiambutosine) therapy.
GMN 2442.2 · https://historyofmedicine.com/id/2927
1957 UMEZAWA, Hamao; ET AL
Production and isolation of a new antibiotic, kanamycin.
With nine co-authors.
GMN 1947.4 · https://historyofmedicine.com/id/2818
1957 UNGAR, Georges (1906 – 1977); ET AL
Pharmacological studies of a new oral hypoglycemic drug.
Phenformin, a biguanide formerly used in diabetes. With L. Freedman and S. L. Shapiro. Clinical report on pp. 193-4.
GMN 3978.3 · https://historyofmedicine.com/id/4770
1957 TRAIN, Percy; ARCHER, William Andrew (1894 – 1973); HEINRICHS, James R.
Medicinal uses of plants by Indian tribes of Nevada. Contributions toward a flora of Nevada. No. 45. Revised edition, with summary of pharmacological research by W. Andrew Archer, Nov. 26, 1957.
Digital facsimile from the Internet Archive at this link. (First published in 1941.)
GMN 9272 · https://historyofmedicine.com/id/11454
1957 SHEEHAN, John Clark (1915 – 1992); HENERY-LOGAN, Kenneth Robert (1921 – 2006)
The total synthesis of penicillin V.
Sheehan and Henery-Logan reported the step by step synthesis of penicillin V (phenoxymethylpenicillin) and the cyclization of the beta lactam ring, key to creation of beta-lactam antibiotics. (Thanks to Juan Weiss for…
GMN 12633 · https://historyofmedicine.com/id/14874
1958 AXELROD, Julius (1912 – 2004); TOMCHICK, R.
Enzymatic O-methylation of epinephrine and other catechols.
The authors discovered the enzyme "COMT" or cathecol-O-methyltransferase, and determined that it was crucial in the methylation and inactivation of adrenergic and other catecholamine type neurotransmitters. (Thanks to…
GMN 1931.6 · https://historyofmedicine.com/id/2761
1958 ARNOLD, Herbert; ET AL
Neuartige Krebs-Chemotherapeutica aus der Gruppe der zyklischen N-Lost-Phosphamidester.
Cyclophosphamide. With F. Bourseaux and N. Brock.
GMN 2660.11 · https://historyofmedicine.com/id/3395
1958 GENTLES, James Clark (1921 – 1987)
Experimental ringworm in guinea pigs: oral treatment with griseofulvin.
Use of griseofulvin in the treatment of ringworm.
GMN 4011.1 · https://historyofmedicine.com/id/5165
1958 –1961 FULTON, John Farquhar (1899 – 1960); QUINBY, Jane (1901 – 1965); STEVENSON, Allan Henry (1903 – 1970); HUNT, Rachel McMasters Miller (1884 – 1963)
Catalogue of botanical books in the collection of Rachel McMasters Hunt. 2 vols. in 3.
Ostensibly the catalogue of Rachel McMasters Hunt's private collection, which she donated to the Hunt Institute for Botanical Documentation at Carnegie Mellon University, this is much more than a finely printed, luxur…
GMN 8744 · https://historyofmedicine.com/id/10922
1958 NISSEN, Claus (1901 – 1975)
Herbals of five centuries. A contribution to medical history and bibliography.
GMN 9740 · https://historyofmedicine.com/id/11927
1959 DAVEY, Thomas Frank (1908 – 1983); HOGERZEIL, L. M.
Diethyl dithiolisophthalate in the treatment of leprosy (ETIP or “Etisul”); a progress report.
Ditophal (Etisul) in leprosy.
GMN 2442.3 · https://historyofmedicine.com/id/2932
1959 RIST, Noël (1906 – 1990); ET AL
Experiments on the antituberculous activity of alpha-ethyl-thioisonicotinamide.
Ethionamide. With F. Grumbach and D. Liberman.
GMN 2353.2 · https://historyofmedicine.com/id/3146
1960 MUELLER, Wolf
Bibliographie des Kaffe, des Kakao der Schokolade, des Tee und deren Surrogate bis zum Jahre 1900.
GMN 13632 · https://historyofmedicine.com/id/15912
1960 ABRAMSON, Harold Alexander (1899 – 1980)
The use of LSD in psychotherapy: Transactions of a conference of D-Lysergic Acid Diethymlamide (LSD-25), April 22, 23 and 24, 1959, Princeton, N. J. Edited by Harold A. Abramson.
GMN 13748 · https://historyofmedicine.com/id/16032
1961 THOMAS, J. P.; ET AL
A new synthetic compound with antituberculous activity in mice; ethambutol (dextro-2, 2’-(ethylenediimino)-di-l-butanol).
Ethambutol for the treatment of tuberculosis. With C. O. Baughn, R. G. Wilkinson and R. G. Shepherd.
GMN 2353.3 · https://historyofmedicine.com/id/3149
1961 YOUNG, James Harvey (1915 – 2006)
The toadstool millionaires.
Chronicles the rise of the patent medicine trade from its beginnings in colonial America until passage of the first federal food and drug law. Digital text available from quackwatch.org at this link.
GMN 12413 · https://historyofmedicine.com/id/14643
1963 BÖTTCHER, Helmuth Maximillian (1895 – 1979)
Miracle drugs: A history of antibiotics.
First published in German, 1959.
GMN 2068.3 · https://historyofmedicine.com/id/2373
1963 WEINSTEIN, Marvin Joseph (1916 – 2011); ET AL
Gentamicin, a new antibiotic complex from Micromonospora.
With nine co-authors.
GMN 1947.5 · https://historyofmedicine.com/id/2820
1963 BROOME, John Denis
Evidence that the L-asparaginase of guinea pig serum is responsible for its antilymphoma effects.
GMN 2660.14 · https://historyofmedicine.com/id/3400
1963 JOHNSON, Irving Stanley (1925 – 2014); ET AL
The Vinca alkaloids: a new class of oncolytic agents.
Clinical use of vinblastine (for Hodgkin’s disease and other lymphomas) and vincristine (for acute leukemias of childhood). With J. G. Armstrong, M. Gorman, and J. P. Burnett. Preliminary communication in J. Lab. clin…
GMN 2660.16 · https://historyofmedicine.com/id/3406
1964 BLACK, Sir James Whyte (1924 – 2010); CROWTHER, Albert Frederick (1917 – 2006); ET AL
A new adrenergic beta-receptor antagonist.
Development of Propranolol, the first beta-blocker effectively used in the treatment of coronary heart disease and hypertension. R. G. Shanks, L. H. Smith and A. C. Dornhorst. In 1988 the Nobel Prize in Physiology or …
GMN 1931.5 · https://historyofmedicine.com/id/2759
1964 MECHOULAM, Raphael (1930 – ); GAONI, Y.
Isolation, structure, and partial synthesis of an active constituent of hashish.
Mechoulam and Gaoni showed that the active ingredient of "one of the most widely used illicit narcotic drugs," the flowering tops of Cannabis sativa, is "pure tetrhydrocannabinol" (THC). This they called the "psychoto…
GMN 14091 · https://historyofmedicine.com/id/16402
1966 HEILMANN, Karl Eugen
Kräuterbücher in Bild und Geschichte.
GMN 2068.9 · https://historyofmedicine.com/id/2407
1966 BAUER, Alfred W.; KIRBY, W. M. M.; SHERRIS, John C.; ET AL
Antibiotic susceptibility testing by a standardized single disk method.
The disk diffusion test, or agar diffusion test, or Kirby–Bauer test (disc-diffusion antibiotic susceptibility test, disc-diffusion antibiotic sensitivity test, KB test), for the antibiotic sensitivity of bacteria. (T…
GMN 11105 · https://historyofmedicine.com/id/13301
1967 HAMARNEH, Sami Khalaf (1925 – 2010)
Index of Arabic manuscripts on medicine and pharmacy at the National Library of Cairo.
GMN 8490 · https://historyofmedicine.com/id/10667
1969 RICHARDS, Hugh Colin; FOSTER, Raymond
A new series of 2-aminomethyltetrahydroquinoline derivatives displaying schistosomicidal activity in rodents and primates.
Oxamniquinine.
GMN 5351.7 · https://historyofmedicine.com/id/6898
1969 KROCHMAL, Arnold (1919 – ); WALTERS, Russell S.; DOUGHTY, Richard M.
A guide to medicinal plants of Appalachia. (U.S.D.A. Forest Service Research Paper NE-138).;
Digital facsimile from www.fs.fed.us at this link.
GMN 8415 · https://historyofmedicine.com/id/10592
1970 BOVÉ, Frank James (1917 – )
The story of ergot.
Exhaustive and well-documented, but no index.
GMN 2068.12 · https://historyofmedicine.com/id/2432
1970 HARE, Ronald (1899 – 1986)
The birth of penicillin.
“Disposes of many myths deeply embedded in the literature” (Macfarlane, see No. 1934).
GMN 2068.15 · https://historyofmedicine.com/id/2452
1970 REES, Richard John William (1917 – 1998); ET AL
Experimental and clinical studies on rifampicin in treatment of leprosy.
With J. M. H. Pearson and M. F. R. Waters.
GMN 2442.5 · https://historyofmedicine.com/id/2936
1971 VANE, Sir John Robert (1927 – 2004)
Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs.
In 1982 Vane shared the Nobel Prize in Physiology or Medicine with Sune Bergström and Bengt Samuelsson for "their discoveries concerning prostaglandins and related biologically active substances."
GMN 13958 · https://historyofmedicine.com/id/16259
1972 MEAD, George R.
The ethnobotany of the California Indians: A compendium of the plants, their users, and their uses.
Revised, expanded, and updated edition, La Grande, OR: E-Cat Worlds, 2014.
GMN 9918 · https://historyofmedicine.com/id/12106
1972 SCHNEIDER, Wolfgang (1912 – 2007)
Geschichte der Pharmazeutischen Chemie.
GMN 12443 · https://historyofmedicine.com/id/14675
1973 AL-BĪRUNĪ, Abū Rayḥān Muḥammad ibn Aḥmad (973 – 1048); SAID, Hakim Mohammed (1920 – 1998)
Al-Biruni's book on pharmacy and materia medica (Kitāb al-saydan fī al-tibb). Edited and translated by Hakim Mohammed Said. 2 vols.
GMN 8524 · https://historyofmedicine.com/id/10701
1975 HAMBERG, Mats; ET AL
Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides.
With J. Stevenson and B. Samuelsson.
GMN 1931.7 · https://historyofmedicine.com/id/2762