1975 KÖHLER, Georges Jean Franz (1946 – 1995); MILSTEIN, César (1927 – 2002)

Continuous cultures of fused cells secreting antibody of predefined specificity.

Hybridomas. In 1984 Köhler and Milstein shared the Nobel Prize in Physiology or Medicine with Niels K. Jerne, "for theories concerning the specificity in development and control of the immune system and the discovery …

GMN 2578.43 · https://historyofmedicine.com/id/4314

1990 WINTER, Sir Gregory Paul (1951 – ); MCCAFFERTY, John; GRIFFITHS, Andrew D.; CHISWELL, David J.

Phage antibodies: Filamentous phage displaying antibody variable domains.

Working in the Laboratory of Molecular Biology at Cambridge University, Winter became interested in the idea that all antibodies have the same basic structure, with only small changes making them specific for one targ…

GMN 14340 · https://historyofmedicine.com/id/16669