1933 MARTÍNEZ MARTÍNEZ, Maximino (1888 – 1964)
Las plantas medicinales de México.
Contains information on 833 species.
GMN 12802 · https://historyofmedicine.com/id/15048
1934 TATUM, Arthur Lawrie (1884 – 1955); COOPER, Garrett Arthur (1904 – )
An experimental study of mapharsen (meta-amino para-hydroxy phenyl arsine oxide) as an antisyphilitic agent.
Introduction of mapharsen.
GMN 2415 · https://historyofmedicine.com/id/3412
1934 RENAUD, Henri-Paul-Joseph (1881 – 1945); COLIN, Georges Séraphin (1893 – 1977)
Tuhfat al-ahbāb: Glossaire de la matière médicale Marocaine.
GMN 8533 · https://historyofmedicine.com/id/10710
1934 DIOSCORIDES, Pedanius [Πεδάνιος Διοσκουρίδης] (40 – 90); GOODYER, John (1592 – 1664); GUNTHER, Robert William Theodore (1869 – 1940)
The Greek herbal of Dioscorides, illustrated by a Byzantine, A.D. 512; Englished by John Goodyer, A.D. 1655; edited and first printed, A.D. 1933, by Robert T. Gunther ... with three hundred and ninety-six illustrations.
Goodyer's translation is considered more of a paraphrase than a translation.
GMN 8564 · https://historyofmedicine.com/id/10741
1935 DOMAGK, Gerhard Johannes Paul (1895 – 1964)
Ein Beitrag zur Chemotherapie der bakteriellen Infektionen.
Introduction of Prontosil, the first drug containing sulfanilamide. In 1939 Domagk was awarded the Nobel Prize in Physiology or Medicine "for the discovery of the antibacterial effects of prontosil."
GMN 1949 · https://historyofmedicine.com/id/2824
1935 BOVET, Daniel (1907 – 1992); TRÉFOUËL, Jacques (1897 – 1977); TRÉFOUËL, Thérèse (1892 – 1978); NITTI, Federico (1903 – 1947)
Activité du p-aminophénylsulfamide sur les infections streptococciques expérimentales de la souris et du lapin.
The Tréfouëls and colleagues assumed that the sulfonamide group was responsible for the results obtained with Domagk’s Prontosil. Their work led them to introduce sulfanilamide.
GMN 1950 · https://historyofmedicine.com/id/2826
1935 DUDLEY, Harold Ward (1887 – 1935); MOIR, John Chassar (1900 – 1977)
The substance responsible for the traditional clinical effect of ergot.
Isolation and introduction of ergometrine.
GMN 6230 · https://historyofmedicine.com/id/7859
1935 UKERS, William Harrison (1873 – 1945)
All about tea. 2 vols.
Covers the historical, technical, scientific, commercial, social and artistic dimensions of tea. Digital facsimile from Google Books at this link.
GMN 13845 · https://historyofmedicine.com/id/16135
1936 COLEBROOK, Leonard (1883 – 1967); KENNY, Méave
Treatment of human puerperal infections, and of experimental infections in mice, with prontosil.
Chemotherapeutic treatment of puerperal sepsis.
GMN 6281 · https://historyofmedicine.com/id/8005
1937 BOVET, Daniel (1907 – 1992); STAUB, Anne-Marie (1914 – 2012)
Action protectrice des éthers phénoliques au cours de l’intoxication histaminique.
First description of structure and action of an antihistamine. In 1957 Bovet was awarded the Nobel Prize in Physiology or Medicine “for his discoveries relating to synthetic compounds that inhibit the action of certai…
GMN 1925 · https://historyofmedicine.com/id/2718
1937 LEVADITI, Constantin (1874 – 1953); VAISMAN, A
La toxi-infection gonococcique expérimentale et son traitement chimiothérapique.
Levaditi and Vaisman showed that sulfanilamide protected mice against gonococcal infection.
GMN 5213.1 · https://historyofmedicine.com/id/7817
1937 DEES, John Essary (1910 – 1993); COLSTON, John Archibald Campbell (1886 – 1971)
The use of sulfanilamide in gonococcic infections. Preliminary report.
GMN 5214.1 · https://historyofmedicine.com/id/7818
1937 –1969 BROOKS, Jerome E. (1895 – 1983); ARENTS, George Jr. (1875 – 1960)
Tobacco: Its history illustrated by the books, manuscripts and engravings in the library of George Arents, Jr. 5 vols. + 10 Supplements.
GMN 11629 · https://historyofmedicine.com/id/13829
1938 ARBER, Agnes Robertson (1879 – 1960)
Herbals: their origin and evolution. A chapter in the history of botany, 1470-1670. 2nd edition.
Includes an invaluable bibliography. Reprinted, with new introduction and additional references, 1987.
GMN 2059 · https://historyofmedicine.com/id/2316
1938 BUTTLE, Gladwin Albert Hurst (1899 – 1983); ET AL
The action of substances allied to 4:4'-diaminodiphenylsulphone in streptococcal and other infections in mice.
G. A. H. Buttle, T. Dewing, G. E. Foster, W. H. Gray, S. Smith, and D. Stephenson discovered the potency of dapsone (DDS).
GMN 1926 · https://historyofmedicine.com/id/2722
1938 WHITBY, Sir Lionel Ernest Howard (1895 – 1956)
Chemotherapy of pneumococcal and other infections with 2-(p-aminobenzenesulphonamido) pyridine.
Experimental proof of the efficacy of sulfapyridine (M & B 693) in pneumococcal pneumonia.
GMN 1951 · https://historyofmedicine.com/id/2827
1938 GAISFORD, Wilfrid Fletcher (1902 – 1988); EVANS, Gladys Mary (1897 – 1973)
Treatment of pneumonia with 2-(p-aminobenzenesulphonamido) pyridine.
Clinical proof of the value of sulphapyridine. M & B 693 (sulphapyridine) treatment of pneumonia. This followed the experimental work of L. E. H. Whitby (see No. 1951).
GMN 1952 · https://historyofmedicine.com/id/2829
1938 ANDERSEN, Dorothy Hansine (1901 – 1963)
Cystic fibrosis of the pancreas and its relation to celiac disease: A clinical and pathological study.
Andersen was the first to describe the characteristic cystic fibrosis of the pancreas, and to correlate it with the lung and intestinal disease prominent in CF. She also was the first to hypotheize that cystic fibrosi…
GMN 13827 · https://historyofmedicine.com/id/16117
1939 EISLER, O; SCHAUMANN, O
Dolantin, ein neuartiges Spasmolytikum und Analgetikum. (Chemisches und pharmakologisches.)
Synthesis of pethidine (dolantin) (Demoral).
GMN 1927 · https://historyofmedicine.com/id/2723
1939 GUNN, James Andrew (1882 – 1958)
The pharmacological actions and therapeutic uses of some compounds related to adrenaline.
GMN 1928 · https://historyofmedicine.com/id/2725
1939 DUBOS, René Jules (1901 – 1982)
Bactericidal effect of an extract of a soil bacillus on gram-positive cocci.
Isolation of gramicidin.
GMN 1933.1 · https://historyofmedicine.com/id/2776
1939 OXFORD, Albert Edward; ET AL
Studies in the biochemistry of micro-organisms. LX. Griseofulvin, C17H17O6Cl, a metabolic product of Penicillium griseo-fulvum Dierckx.
Isolation of griseofulvin. With H. Raistrick and P. Simonart.
GMN 1933.2 · https://historyofmedicine.com/id/2780
1939 MÜLLER, Franz Hermann
Tabakmissbrauch und Lungencarcinom.
In the first case-control epidemiological study of the effects of tobacco Müller recorded a statistically significant correlation between cigarette smoking and lung cancer. See Alfredo Morabia, "Quality, originality, …
GMN 3213 · https://historyofmedicine.com/id/4354
1939 PLATEARIUS, Matthaeus (1130 – 1180); WÖLFEL, Hans
Das Arzneidrogenbuch Circa Instans in einer Fassung des XIII. Jahrhunderts aus der Universitätsbibliothek Erlangen. Text und Kommentar als Beitrag zur Pflanzen- und Drogenkunde des Mittelalters by Hans Wölfel.
GMN 8449 · https://historyofmedicine.com/id/10626
1940 CRUZ, Martin De La; EMMART, Emily Walcott (1898 – ); BADIANO, Juan (1484 – 1552)
The Badianus manuscript. (Codex Barberini, Latin, 241) Vatican Library. An Aztec herbal of 1552. Edited and translated by Emily W. Emmart.
The earliest complete Mexican medical text and the only medical text known to be the work of native Aztecs. Written by an Aztec physician named by the Spanish Martin de la Cruz, and translated into Latin by another na…
GMN 1811.1 · https://historyofmedicine.com/id/2009
1940 ABRAHAM, Sir Edward Penley (1913 – 1999); CHAIN, Sir Ernst Boris (1906 – 1979)
An enzyme from bacteria able to destroy penicillin.
Penicillinase.
GMN 1933.3 · https://historyofmedicine.com/id/2781
1940 CHAIN, Sir Ernst Boris (1906 – 1979); FLOREY, Howard Walter (1898 – 1968); HEATLEY, Norman George (1911 – 2004); GARDNER, Andrew Duncan (1884 – 1977); SANDERS, A. G.; JENNINGS, Margaret Augusta (1904 – 1994); ORR-EWING, J.
Penicillin as a chemotherapeutic agent.
Proof of the therapeutic action in vivo of penicillin against streptococcal and other bacterial infections. Building upon Fleming’s work (No. 1933 and 10784), the consequences of which had originally been widely unapp…
GMN 1934 · https://historyofmedicine.com/id/2783
1940 GSELL, Otto (1902 – 1990)
Chemotherapie akuter Infektionskrankheiten durch Ciba 3714 (Sulfanilamidothiazol).
First important clinical trial of sulfathiazole.
GMN 1953 · https://historyofmedicine.com/id/2831
1940 MARSHALL, Eli Kennerly Jr. (1889 – 1966); ET AL
Sulfanilylguanidine: a chemotherapeutic agent for intestinal infections.
Sulphaguanidine was introduced by E. K. Marshall, A. C. Bratton, H. J. White, and J. T. Litchfield.
GMN 1954 · https://historyofmedicine.com/id/2833
1940 ROBLIN, Richard Owen Jr. (1907 – 1985); ET AL
Chemotherapy, II. Some sulfanilamido heterocycles.
Synthesis of sulphamerazine, by R. O. Roblin, J. H. Williams, P. S. Winnek, and J. P. English.
GMN 1955 · https://historyofmedicine.com/id/2835
1940 WOODS, Donald Devereux (1912 – 1964)
The relation of p-amniobenzoic acid to the mechanism of the action of sulphanilamide.
Isolation of p-aminobenzoic acid, a structural analog of sulfanilamide.
GMN 1955.1 · https://historyofmedicine.com/id/2837
1940 MEYERHOF, Max (1874 – 1945); MAIMONIDES, (Moses ben Maimon; מֹשֶׁה בֶּן־מַימוֹן; Mōšeh bēn-Maymōn; موسى بن ميمون Mūsā bin Maymūn) (1135 – 1204)
Sarh Asma Al-Uqqar (L'Explication des noms de drogues) Un glossaire de matière medicale composé par Maïmonide. Texte publié pour la première fois d'après le manuscrit unique
GMN 11241 · https://historyofmedicine.com/id/13438
1941 HAGGIS, Alec William (1889 – 1946)
Fundamental errors in the early history of cinchona.
GMN 2060 · https://historyofmedicine.com/id/2326
1941 ABRAHAM, Sir Edward Penley (1913 – 1999); CHAIN, Sir Ernst Boris (1906 – 1979); FLOREY, Howard Walter (1898 – 1968); HEATLEY, Norman George (1911 – 2004); GARDNER, Andrew Duncan (1884 – 1977); JENNINGS, Margaret Augusta (1904 – 1994); FLETCHER, Charles M.
Further observations on penicillin.
First report of the chemotherapeutic action of penicillin on humans (10 cases).
GMN 1934.1 · https://historyofmedicine.com/id/2785
1941 FINLAND, Maxwell (1902 – 1987); ET AL
Sulfadiazine. Therapeutic evaluation and toxic effects on four hundred and forty-six patients.
Introduction of sulphadiazine. With E. Strauss and O. L. Peterson.
GMN 1956 · https://historyofmedicine.com/id/2839
1941 POTH, Edgar Jacob (1899 – ); KNOTTS, Frank Louis (1912 – 1989)
Succinyl sulfathiazole, a new bacteriostatic agent locally active in the gastrointestinal tract.
Introduction of sulfasuxidine.
GMN 1957 · https://historyofmedicine.com/id/2842
1941 WYMAN, Leland Clifton (1897 – 1988); HARRIS, Stuart K.
Navajo Indian medical ethnobotany. University of New Mexico Bulletin, Anthropological Series, Vol. 3, No. 5.
Digital facsimile from herbaltherapeutics.net at this link.
GMN 9281 · https://historyofmedicine.com/id/11463
1942 MACARTNEY, Donald William; ET AL
Sulphamethazine: Clinical trial of a new sulphonamide.
Sulfadimidine (also spelled Sulphadimidine) with G. S. Smith, R. W. Luxton, W. A. Ramsay, and J. Goldman. [Also designated as Vol. 239 by publishers of The Lancet.]
GMN 1958 · https://historyofmedicine.com/id/2844
1942 RICH, Arnold Rice (1893 – 1968)
The rôle of hypersensitivity in periarteritis nodosa; as indicated by seven cases developing during serum sickness and sulfonamide therapy.
Rich considered hypersensitivity to be an important factor in the aetiology of periarteritis nodosa.
GMN 2924 · https://historyofmedicine.com/id/4922
1942 ABRAHAM, Sir Edward Penley (1913 – 1999); CHAIN, Sir Ernst Boris (1906 – 1979)
Purification of penicillin.
Abraham and Chain first announced the purification of penicillin, a critical step before production of the drug could begin, in a two paragraph paper published on a single page of Nature on March 21, 1942. The method,…
GMN 14282 · https://historyofmedicine.com/id/16605
1943 STOLL, Arthur (1887 – 1971); HOFMANN, Albert (1906 – 2008)
Partialsynthese von Alkaloiden vom Typus des Ergobasins.
Synthesis of lysergic acid diethylamide (LSD).
GMN 1928.1 · https://historyofmedicine.com/id/2727
1943 ABRAHAM, Sir Edward Penley (1913 – 1999); CHAIN, Sir Ernst Boris (1906 – 1979); ROBINSON, Sir Robert (1886 – 1975); ET AL
Penicillamine, a characteristic degradation product of penicillin.
With W. Baker.
GMN 1934.2 · https://historyofmedicine.com/id/2786
1943 FAGET, Guy Henry (1891 – 1947); ET AL
The promin treatment of leprosy. A progress report.
Promin (sodium glucosulphone) introduced in the treatment of leprosy. With R. C. Pogge, F. A. Johansen, J. F. Dinan, B. M. Prejean, and C. G. Eccles.
GMN 2441 · https://historyofmedicine.com/id/2921
1943 MAHONEY, John Friend (1889 – 1957); ARNOLD, Richard C. (1906 – 1992); HARRIS, Ad
Penicillin treatment of early syphilis. A preliminary report.
Mahoney and colleagues introduced penicillin in treatment of syphilis. This was the report of the first four cases of patients with early stages of the disease. Digital facsimile of the version published in the the Am…
GMN 2418 · https://historyofmedicine.com/id/3422
1943 HERRELL, Wallace Edgar (1909 – 1992); ET AL
Use of penicillin in sulfonamide resistant gonorrheal infections.
With E. N. Cook and L. Thompson.
GMN 5214.1 · https://historyofmedicine.com/id/7820
1944 ROSENBERG, David Harry (1903 – ); ARLING, Philip Arthur (1908 – 1955)
Penicillin in the treatment of meningitis.
GMN 4689.1 · https://historyofmedicine.com/id/970
1944 DODD, Matthew Charles (1910 – 1981); STILLMAN, William Barlow (1904 – 1987)
The in vitro bacteriostatic action of some simple furan derivatives.
Nitrofuran (nitrofurazone).
GMN 1928.2 · https://historyofmedicine.com/id/2729
1944 SCHATZ, Albert (1920 – 2005); WAKSMAN, Selman Abraham (1888 – 1973); GREGORY, Elizabeth Bugie
Streptomycin, a substance exhibiting antibiotic activity against Grampositive and Gram-negative bacteria.
Introduction of streptomycin. Order of authorship: Schatz, Gregory, Waksman. In 1952 Waksman was awarded the Nobel Prize in Physiology or Medicine "for ingenious, systematic, and successful studies of the soil microbe…
GMN 1935 · https://historyofmedicine.com/id/2788
1944 MUIR, Ernest (1880 – 1974)
Preliminary report on diasone in the treatment of leprosy.
Muir found diasone (a sulphone) valuable in the treatment of leprosy.
GMN 2442 · https://historyofmedicine.com/id/2923
1944 HADDOW, Sir Alexander (1907 – 1976); ET AL
Influence of synthetic oestrogens upon advanced malignant disease.
Administration of synthetic estrogens in advanced mammary cancer caused regression of tumors. With J. M. Watkinson, E. Paterson, and P. C. Koller.
GMN 2659.3 · https://historyofmedicine.com/id/3355
![DIOSCORIDES, Pedanius [Πεδάνιος Διοσκουρίδης] (40 – 90)](/media/portraits/2028)
