1944 MUIR, Ernest (1880 – 1974)
Preliminary report on diasone in the treatment of leprosy.
Muir found diasone (a sulphone) valuable in the treatment of leprosy.
GMN 2442 · https://historyofmedicine.com/id/2923
1944 –1948 KEFFER, Luiza
Indice bibliográfico de lepra, 1560-1943. 3 vols.
Supplements 1-5, 1952-62.
GMN 2447 · https://historyofmedicine.com/id/2944
1944 RICH, Arnold Rice (1893 – 1968)
The pathogenesis of tuberculosis.
Classic work on the pathogenesis of tuberculosis and its immunology and hypersensitivity.
GMN 2349.1 · https://historyofmedicine.com/id/3122
1944 EATON, Monroe Davis (1904 – ); ET AL
Studies on the etiology of primary atypical pneumonia. A filterable agent transmissible to cotton rats, hamsters, and chick embryos.
The Eaton agent, isolated from primary atypical pneumonia. With G. Meiklejohn and W. van Herick.
GMN 3213.1 · https://historyofmedicine.com/id/4356
1944 MACCALLUM, Frederick Ogden; BRADLEY, W. H.
Transmission of infective hepatitis to human volunteers.
MacCallum and Bradley finally proved the nature of both serum and infective hepatitis.
GMN 3664.2 · https://historyofmedicine.com/id/4815
1944 YEOMANS, Andrew (1907 – ); ET AL
The therapeutic effect of para-aminobenzic acid in louse-borne typhus fever.
With J. C. Snyder, E. S. Murray, C. J. D. Zarafonetis, and R. S. Ecke.
GMN 5398.3 · https://historyofmedicine.com/id/7199
1944 ORDMAN, Charles William (1914 – ); ET AL
Chemical, clinical, and immunological studies on the products of human plasma fractionation. XII. The use of concentrated normal human serum gamma globulin (human immune serum globulin) in the prevention and attenuation of measles.
Gamma globulin used for passive immunization against measles. With C. G. Jennings and C. A. Janeway.
GMN 5449.1 · https://historyofmedicine.com/id/7494
1944 HUFF, Clay G. (1900 – ); COULSTON, Frederick (1914 – 2003)
The development of Plasmodium gallinaceum from sporozoite to erythrocytic trophozoite.
First detailed account of the full cycle of development of the avian malaria parasite P. gallinaceum.
GMN 5259.2 · https://historyofmedicine.com/id/8544
1944 JONES, Thomas Duckett (1899 – 1954)
The diagnosis of rheumatic fever.
The Jones criteria (later revised in 1992 and 2015) for the diagnosis of acute rheumatic fever.
GMN 12365 · https://historyofmedicine.com/id/14589
1945 FELDMAN, William Hugh (1892 – 1974); HINSHAW, Horton Corwin (1902 – 2001)
Streptomycin in treatment of clinical tuberculosis: a preliminary report.
GMN 2350 · https://historyofmedicine.com/id/3125
1945
Transmission of primary atypical pneumonia to human volunteers.
COMMISSION ON ACUTE RESPIRATORY DISEASES
GMN 3214 · https://historyofmedicine.com/id/4357
1945 FULTON, Forrest (1913 – 1971); JOYNER, L
Cultivation of Rickettsia tsutsugamushi in lungs of rodents. Preparation of a scrub-typhus vaccine.
Scrub-typhus vaccine.
GMN 5399 · https://historyofmedicine.com/id/7205
1945 SABIN, Albert Bruce (1906 – 1993); SCHLESINGER, Robert Walter (1913 – 2003)
Production of immunity to dengue with virus modified by propagation in mice.
Successful propagation of dengue in mice and production of a vaccine.
GMN 5475.1 · https://historyofmedicine.com/id/7622
1945 CURD, Francis Henry Swinton (1909 – 1948); ET AL
Studies on synthetic antimalarial drugs.
F. H. S. Curd, D. G. Davey, and F. L. Rose synthesized proguanil (“paludrine”) and first tested it in avian malaria.
GMN 5260 · https://historyofmedicine.com/id/8545
1945 ADAMS, Alfred Robert Davies (1901 – 1992)
Studies on synthetic antimalarial drugs. XIII. Results of a preliminary investigation of the therapeutic action of 4888 (paludrine) on acute attacks of benign tertian malaria.
First use of proguanil in human malaria. With B. G. Maegraith, J. D. King, R. H. Townsend, T. H. Davey, and R. E. Havard.
GMN 5261 · https://historyofmedicine.com/id/8546
1945 STEARN, Allen Edwin (1894 – ); STEARN, Esther Wagner
The effect of smallpox on the destiny of the Amerindian.
GMN 13801 · https://historyofmedicine.com/id/16088
1946 DOMAGK, Gerhard Johannes Paul (1895 – 1964); ET AL
Ueber eine neue, gegen Tuberkelbazillen in vitro wirksame Verbindungsklasse.
Introduction of thiosemicarbazone in treatment of tuberculosis. With R. Behnisch, F. Mietzsch, and H. Schmidt.
GMN 2351 · https://historyofmedicine.com/id/3129
1946 HART, Philip Montagu D'Arcy (1900 – 2006)
Chemotherapy of tuberculosis. Researches during the past 100 years.
GMN 2359 · https://historyofmedicine.com/id/3167
1946 HARRIS, A
A microflocculation test for syphilis using cardiolipin antigen: preliminary report.
V. D. Research Laboratory test (Harris test). With A. A. Rosenberg and L. M. Riedel.
GMN 2418.1 · https://historyofmedicine.com/id/3423
1946 FOSHAY, Lee (1896 – 1960); PASTERNACK, A. Bernard (1916 – )
Streptomycin treatment of tularemia.
GMN 5180 · https://historyofmedicine.com/id/6293
1946 ENDERS, John Franklin (1897 – 1985); STOKES, Joseph Jr. (1896 – 1972); ET AL
Immunity in mumps. VI. Experiments on the vaccination of human beings with formolized mumps virus.
With E. P. Maris, and L. W. Kane.
GMN 5544.2 · https://historyofmedicine.com/id/6756
1946 KIKUTH, Walter (1896 – 1968); ET AL
Miracil, ein neues Chemotherapeuticum gegen die Darmbilharziose.
Lucanthone hydrochloride (Miracil D). With R. Gönnert and H. Mauss.
GMN 5351.2 · https://historyofmedicine.com/id/6883
1946 HUEBNER, Robert Joseph (1914 – 1998); ET AL
Rickettsialpox. A newly recognized rickettsial disease. IV. Isolation of a rickettsia apparently identical with the causative agent of rickettsialpox from Allodermanyssus sanguineus, a rodent mite.
Isolation of Rickettsia akari, aetiologic agent of rickettsialpox. With W. L. Jellison and C. Pomerantz.
GMN 5400 · https://historyofmedicine.com/id/7212
1946 SUSSMAN, Leon Nathaniel (1907 – 2000)
Kew Gardens spotted fever.
Rickettsialpox described.
GMN 5401 · https://historyofmedicine.com/id/7215
1946 MOST, Harry (1907 – 1994); LONDON, Irving M. (1918 – 2018); LAVIETES, Paul Harold (1907 – 1990)
Chloroquine for treatment of acute attacks of vivax malaria.
Harry Most led the development of chloroquine for use in treating American troops suffering from malaria. At the beginning of the American involvement in the war there were more American casualties from malaria than f…
GMN 5261.1 · https://historyofmedicine.com/id/8547
1947 HEWITT, Reginald Irving (1911 – ); ET AL
Experimental chemotherapy of filariasis. III. Effect of 1-diethylcarbamyl-4-methyl-piperazine hydrochloride against naturally acquired filarial infections in cotton rats and dogs.
Proof of antifilarial action of diethylcarbarmazine citrate (hetrazan). With S. Kushner, H. W. Stewart, E. White, W. S. Wallace, and Y. Subbarow.
GMN 5351.3 · https://historyofmedicine.com/id/6884
1947 VAN HOOF, L.
Sur la chimiothérapie de l’onchocercose. (Note préliminaire).
First effective chemotherapy (suramin) for onchocerciasis. With C. Heurard, E. Peel, and M. Wanson.
GMN 5351.4 · https://historyofmedicine.com/id/6887
1947 SMADEL, Joseph Edwin (1907 – 1963); JACKSON, Elizabeth B.
Chloromycetin, an antibiotic with chemotherapeutic activity in experimental rickettsial and viral infections.
Introduction of chloramphenicol, used in treatment of typhus.
GMN 1940 · https://historyofmedicine.com/id/8617
1948 HARKNESS, Arthur Herbert (1889 – 1970); BROWNLEE, G
Leprosy treated with sulphetrone in 1943.
Clinical use of solapsone (sulphetrone).
GMN 2442.1 · https://historyofmedicine.com/id/2925
1948 OUCHTERLONY, Örjan Thomas Gunnersson (1914 – 2004)
In vitro method for testing the toxin-producing capacity of diphtheria bacteria.
Agar gel immunodiffusion.
GMN 2578.6 · https://historyofmedicine.com/id/4143
1948 CHRISTIE, Ronald Victor (1902 – 1986)
Penicillin in subacute bacterial endocarditis. Report to the Medical Research Council on 269 patients treated in 14 centres appointed by the Penicillin Clinical Trials Committee.
GMN 2880 · https://historyofmedicine.com/id/4224
1948 POPPE, John Karl (1911 – 2012)
Cellophane treatment of syphilitic aneurysms with report of results in six cases.
GMN 2993 · https://historyofmedicine.com/id/5273
1948 DALLDORF, Gilbert Julius (1900 – 1979); SICKLES, Grace Mary (1898 – 1959)
An unidentified, filterable agent isolated from the feces of children with paralysis.
Isolation of the Coxsackie virus from the stool of a patient residing in Coxsackie, New York.
GMN 5545 · https://historyofmedicine.com/id/6761
1948 ALVING, Alf Sven (1902 – 1965)
Pentaquine (Sn-13,276), a therapeutic agent effective in reducing the relapse rate in vivax malaria.
Clinical trials of pentaquine. With B. Craige, R. Jones, C. M. Whorton, T. N. Pullman, and L. Eichelberger.
GMN 5261.2 · https://historyofmedicine.com/id/8548
1948 SHORTT, Henry Edward (1887 – 1987); ET AL
The pre-erythrocytic stage of mammalian malaria.
Demonstration of the pre-erythrocytic stage of P. cynomolgi in the monkey. With P. C. C. Garnham and B. Malamos. Preliminary communication in Nature (Lond.), 1948, 161, 126.
GMN 5262 · https://historyofmedicine.com/id/8549
1948 SHORTT, Henry Edward (1887 – 1987)
The pre-erythrocytic stage of human malaria Plasmodium vivax.
With P. C. C. Garnham, G. Covell, and P. G. Shute.
GMN 5262.1 · https://historyofmedicine.com/id/8550
1948 MASSELL, Benedict Frank (1906 – 2008); DOW, J. W.; JONES, Thomas Duckett (1899 – 1954)
Orally administered penicillin in patients with rheumatic fever.
Massell and colleagues demonstrated that rheumatic fever could be prevented by penicillin treatment of streptococcal throat infections. (Order of authorship in the original publication: Massell, Dow, Jones.) See also:…
GMN 12359 · https://historyofmedicine.com/id/14583
1949 HENCH, Philip Showalter (1896 – 1965); KENDALL, Edward Calvin (1886 – 1972)
The effects of the adrenal cortical hormone 17-hydroxy-11-dehydrocorticosterone (compound E) on the acute phase of rheumatic fever: preliminary report.
Compound E (cortisone) introduced in the treatment of rheumatic fever. With C. H. Slocumb, A. R. Barnes, H. L. Smith, H. F. Polley.
GMN 4509 · https://historyofmedicine.com/id/356
1949 ENDERS, John Franklin (1897 – 1985); WELLER, Thomas Huckle (1915 – 2008); ROBBINS, Frederick Chapman (1916 – 2003)
Cultivation of the Lansing strain of poliomyelitis virus in cultures of various human embryonic tissues.
Enders, Weller, and Robbins grew the poliomyelitis virus in cultures of different tissues. Their method proved of great value in virus research, and removed the final obstacles to vaccine production. In 1974 Enders, W…
GMN 4671.1 · https://historyofmedicine.com/id/874
1949 NELSON, Robert Armstrong (1921 – ); MAYER, Manfred Martin (1916 – 1984)
Immobilization of Treponema pallidum in vitro by antibody produced in syphilitic infection.
Nelson’s treponemal immobilization test.
GMN 2419 · https://historyofmedicine.com/id/2875
1949 TAYLOR, Richard Moreland (1887 – 1981)
Studies on survival of influenza-virus between epidemics and antigenic variants of the virus.
Recovery of influenza C virus.
GMN 5500 · https://historyofmedicine.com/id/6464
1949 CUTTINO, John Tindal (1912 – 1988); MCCABE, Anne M.
Pure granulomatous nocardiosis: a new fungus disease distinguished by intracellular parasitism. A description of a new disease in man due to a hitherto undescribed organism, Nocardia intracellularis, n.sp., including a study of the biological and pathogenic properties of this species.
Nocardiosis described.
GMN 5515 · https://historyofmedicine.com/id/6522
1949 CURNEN, Edward Charles Jr. (1909 – 1997); MELNICK, Joseph Louis (1914 – 2001); ET AL
Disease resembling nonparalytic poliomyelitis associated with a virus pathogenic for infant mice.
Isolation of the Coxsackie virus from patients with poliomyelitis. With E. W. Shaw.
GMN 5546 · https://historyofmedicine.com/id/6763
1949 BOUILLON, Albert
Bibliographie des schistosome et des schistosomiases (bilharzioses) humaines et animales de 1931 á 1948.
Continues and supplements No. 5352.
GMN 5352.1 · https://historyofmedicine.com/id/6912
1949 STOKER, Sir Michael George Parke (1918 – 2013)
Serological evidence of Q fever in Great Britain.
Relationship of primary atypical pneumonia and Q fever.
GMN 5402.1 · https://historyofmedicine.com/id/7237
1949 BEDSON, Sir Samuel Phillips (1886 – 1969); ET AL
The laboratory diagnosis of lymphogranuloma venereum.
Skin-test antigen. With C. F. Barwell, E. J. King, and L. W. J. Bishop.
GMN 5225 · https://historyofmedicine.com/id/7842
1949 SHORTT, Henry Edward (1887 – 1987)
The pre-erythrocytic stage of Plasmodium falciparum. A preliminary note.
With N. H. Fairley, G. Covell, P. G. Shute, and P. C. C. Garnham. See also Trans. roy. Soc. trop. Med. Hyg., 1951, 44, 405-19.
GMN 5262.2 · https://historyofmedicine.com/id/8551
1949 POWELL, John Harvey (1914 – 1971)
Bring out your dead: The great plague of yellow fever in Philadelphia in 1793.
Reprinted with a new introduction by Kenneth R. Foster, Mary F. Jenkins, and Anna Coxe Toogood (Philadelphia: University of Pennsylvania Press, 1993).
GMN 9384 · https://historyofmedicine.com/id/11567
1950 FRAPPIER, Armand (1904 – 1991); GUY, Roland (1913 – )
A new and practical B.C.G. skin test (the B.C.G. scarification test) for the detection of the total tuberculous allergy.
GMN 2352 · https://historyofmedicine.com/id/3132
1950 FLORIO, Lloyd Joseph (1910 – 1975); ET AL
Colorado tick fever. Isolation of the virus from Dermacentor andersoni in nature and a laboratory study of the transmission of the virus in the tick.
Isolation of the virus of Colorado tick fever. With M. S. Miller and E. R. Mugrage.
GMN 5546.1 · https://historyofmedicine.com/id/6766
