2020 WRAPP, Daniel; WANG, Nianshuang; CORBETT, Kizzmekia Shanta (1986 – ); GRAHAM, Barney S.; ET AL
Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation.
Posted online on February 17, 2020. 2019-nCoV was an interim name for the Novel Coronavirus. These studies, which included the 3D structure of the RBD (receptor binding domain) within the S protein, provided informati…
GMN 13483 · https://historyofmedicine.com/id/15757
2020 SHIN, Matthew D.; SHUKLA, Sourabh; CHUNG, Young Hun; STEINMETZ, Nicole F.; ET AL
COVID-19 vaccine development and a potential nanomaterial path forward.
Published 15 July 2020. Order of authorship in original publication: Shin, Shukla, Chung....Steinmetz. Probably the first publication on the type of nanotechnology involved in production of the Moderna and Pfizer mRNA…
GMN 13484 · https://historyofmedicine.com/id/15758
2020 POLACK, Fernando P.; THOMAS, Stephen J.; KITCHIN, Nicholas; ET AL
Safety and efficacy of the BNT162b2 mRNA Covid-19 vaccine.
BNT162b2 is synonomous with the Pfizer BioNTech mRNA Covid-19 vaccine. The Pfizer-BioNTech mRNA vaccine was produced from theoretical design to finished product and distribution in less than one year. This was the fir…
GMN 13506 · https://historyofmedicine.com/id/15781
2020 ROTHE, Camilla (1974 – ); SCHUNK, Mirjam; SOTHMANN, Peter; ET AL
Correspondence. Transmission of 2019 nCoV infection from an asymptomatic contact in Germany.
Posted online 1-30-20, updated 2-6-20, and published in print on March 5, 2020. First report of the "asymptomatic transmission" of Covid-19. The authors wrote, “The fact that asymptomatic persons are potential sources…
GMN 13519 · https://historyofmedicine.com/id/15794
2020 JONES, Veena Goel; MILLS, Marcos; SUAREZ, Dominique Marie; ET AL
Covid-19 and Kawasaki disease: Novel virus and novel case.
Published online 4-7-20; in print in June, 2020. First case report of what became known as Multisystem Inflammatory Syndrome in Children (MIS-C), sometimes present with Kawasaki disease. This is one of the worst compl…
GMN 13520 · https://historyofmedicine.com/id/15795
2020 BAUM, Alina; AJITHDOSS, Dharani K.; KYRATSOUS, Christos A.; ET AL
REGN-COV2 antibodies prevent and treat SARS-CoV-2 infection in rhesus macaques and hamsters.
The authors, working at Regeneron, showed that a cocktail of two potent neutralizing monoclonal antibodes reduced virus load in the airways and diminshed viral induced pathological sequelae when given both as a prophy…
GMN 13523 · https://historyofmedicine.com/id/15799
2021 BADEN, Lindsey Robert; EL SAHLY, Hana M.; ESSINK, Brandon; ET AL
Efficacy and safety of the mRNA-1273 SARSCov-2 vaccine.
mRNA-1273 is synonymous with the Moderna mRNA Covid-19 vaccine. The Moderna mRNA vaccine was produced from theoretical design to finished product and distribution in less than one year. This was the first published pa…
GMN 13507 · https://historyofmedicine.com/id/15782
2021 WEINREICH, David. M.; SIVAPALASINGAM, Sumathi; NORTON, Thomas; ET AL
REGN-COV-2, a neutralizing antibody cocktail, in outpatients with Covid-19.
The authors showed that the Regeneron antibody cocktail has a low incidence of side effects and a profound and rapid effect on viral load, with most reduction occurring within 48 hours, even in patents with the highes…
GMN 13524 · https://historyofmedicine.com/id/15800
2022 SCHWARTZ, David Alan (1953 – ); AVVAD-PORTARI, Elyzabeth; BABÁL, Pavel; ET AL
Placental tissue destruction and insufficiency from COVID-19 causes stillbirth and neonatal death from hypoxic-ischemic injury: A study of 68 cases with SARS-CoV-2 placentitis from 12 countries.
Order of authorship in the original publication: Schwartz, Avvad-Portari, Babál, et al.... "Design.—Case-based retrospective clinico-pathological analysis by a multinational group of 44 perinatal specialists from 12 c…
GMN 13814 · https://historyofmedicine.com/id/16103
2022 LEMEY, Phillippe; WOROBEY, Michael; LEVY, Joshua I.; ET AL
The Huanan seafood wholesale market in Wuhan was the early epicenter of the COVID-19 pandemic.
Worobey and colleagues showed: 1) The earliest case of an abnormal pneumonia was first reported to the World Health Organization on Dec. 31, 2019. 2) Using basic epidemiology going back to the now iconic plot maps dra…
GMN 14168 · https://historyofmedicine.com/id/16483
2022 WOROBEY, Michael; PEKAR, Jonathan E.; PARKER, Edyth; ET AL
The molecular epidemiology of multiple zoonotic origins of SARS-Co-V-2.
Abstract: "We analyzed the genomic diversity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) early in the coronavirus disease 2019 (COVID-19) pandemic. We show that SARS-CoV-2 genomic diversity before …
GMN 14169 · https://historyofmedicine.com/id/16484
