1907 WHIPPLE, George Hoyt (1878 – 1976)
A hitherto undescribed disease characterized anatomically by deposits of fat and fatty acids in the intestinal and mesenteric lymphatic tissues.
“Whipple’s disease”. Whipple suggested the name lipodystrophia intestinalis (intestinal lipodystrophy) for this condition because there were abnormal lipid deposits in the small intestine wall. In figure 9 of his pape…
GMN 3782 · https://historyofmedicine.com/id/4680
1961 YARDLEY, John Howard (1926 – 2011); HENDRIX, Thomas Russell (1920 – 2013)
Combined electron and light microscopy in Whipple's disease. Demonstration of "bacillary bodies" in the intestine.
Order of authorship in the original publication: Yardley, Hendrix. The authors made the first observations of previously uncultured, unseen and unidentified bacilli associated with Whipple's disease, suggesting that i…
GMN 11979 · https://historyofmedicine.com/id/14187
1992 RELMAN, David Arnold; SCHMIDT, Thomas M.; MACDERMOTT, Richard P.; ET AL
Identification of the uncultured bacillus of Whipple's disease.
Order of authorship in the original publication: Relman, Schmidt, MacDermott....The authors used 16S ribosomal RNA sequencing to identify the bacillus associated with Whipple's disease that had resisted culturing meth…
GMN 11980 · https://historyofmedicine.com/id/14188
2000 RAOULT, Didier (1952 – ); BIRG, Marie-Laure; LA SCOLA, Bernard; ET AL
Cultivation of the bacillus of Whipple's disease.
Order of authorship in the original publication: Raoult, Birg, La Scola. Raoult and colleagues cultured the bacterium causing the systemic digestive tract infection Whipple's disease from a mitral valve of a patient w…
GMN 11981 · https://historyofmedicine.com/id/14189
2006 RAOULT, Didier (1952 – ); BIRG, Marie-Laure; FENOLLAR, Florence
Culture of T. whipplei from the stool of a patient with Whipple's disease.
Order of authorship in the original publication: Raoult, Fenollar, Birg. Raoult and colleagues cultured the infectious agent of Whipple's disease from the stool of a patient with the disease. In the process the author…
GMN 11982 · https://historyofmedicine.com/id/14190
