1885 –1887 FILATOV, Nil Feodorovich (1847 – 1902)

Lektsii ob ostrikh infektsionnîkh bolierznyakh u dietei. [Lectures on acute infectious diseases of children.] 2 vols.

Glandular fever (infectious mononucleosis) was first described by Filatov under the name of idiopathic adenitis (“Filatov’s disease”). A German translation of his book appeared in 1895-97.

GMN 5485 · https://historyofmedicine.com/id/6418

1889 PFEIFFER, Emil (1846 – 1921)

Drüsenfieber.

“Pfeiffer’s disease”. He is sometimes credited with the original description of infectious mononucleosis, ascribed to Filatov. Pfeiffer’s paper is a most comprehensive discussion of the clinical aspects of the disease.

GMN 5486 · https://historyofmedicine.com/id/6421

1920 SPRUNT, Thomas Peck (1884 – 1955); EVANS, Frank Alexander (1889 – 1956)

Mononucleosis leukocytosis in reaction to acute infections (“infectious mononucleosis”).

Classic account, with first use of the term “infectious mononucleosis”.

GMN 5486.1 · https://historyofmedicine.com/id/6423

1932 PAUL, John Rodman (1893 – 1971); BUNNELL, Walls Willard (1902 – 1965)

The presence of heterophile antibodies in infectious mononucleosis.

The Paul–Bunnell test for the diagnosis of infectious mononucleosis.

GMN 5487 · https://historyofmedicine.com/id/6425

1964 EPSTEIN, Michael Anthony (1921 – ); BARR, Yvonne (1932 – 2016)

Cultivation in vitro of human lymphoblasts from Burkitt’s malignant lymphoma.

Order of authorship in the original publication: Epstein, Barr. Discovery of the Epstein-Barr virus, a human herpes virus causing infectious mononucleosis, and implicated in Burkitt’s lymphoma and other forms of cance…

GMN 2660.17 · https://historyofmedicine.com/id/3410

1968 HENLE, Gertrude Szpingier (1912 – 2006); HENLE, Werner (1910 – 1987); DIEHL, Volker S. (1938 – )

Relation of Burkitt’s tumor-associated herpes-type virus to infectious mononucleosis.

The Henles and Diehl showed that Epstein-Barr virus is the aetiological agent in infectious mononucleosis.

GMN 5487.1 · https://historyofmedicine.com/id/6427

2020 FEDER, Henry M. Jr.; REZUKE, William N.

Infectious mononucleosis diagnosed by Downey cells: Sometimes the old ways are better.

The Downey cell method for the diagnosis of infectious mononucleosis remains effective and cost-effective nearly 100 years after it was discovered: "An 18-year-old woman visited her physician because she had a fever, …

GMN 12117 · https://historyofmedicine.com/id/14326