1554 FERNEL, Jean François (1497 – 1558)
Medicina. 3 pts.
The first systematic treatise on pathology, which also introduced the names for the sciences of pathology and physiology. In the second part, entitled “Pathologia”, Fernel provided the first systematic essay on the su…
GMN 2271 · https://historyofmedicine.com/id/2838
1777 –1781 SANDIFORT, Eduard (1742 – 1814)
Observationes anatomicae-pathologicae. 4 vols.
Sandifort’s beautifully illustrated work on pathological anatomy included records of ulcerative aortic endocarditis, renal calculi, hemias, bony ankyloses, and congenital abnormalities. A good account of the “tetralog…
GMN 2278 · https://historyofmedicine.com/id/2893
1809 DUNDAS, David
An account of a peculiar disease of the heart.
Account of nine cases of rheumatic endocarditis.
GMN 2739 · https://historyofmedicine.com/id/4574
1809 BURNS, Allan (1781 – 1813)
Observations on some of the most frequent and important diseases of the heart.
Burns described endocarditis and reported three cases of mitral stenosis. He recognized the thrill present in the latter condition and seems to have understood the mechanism of a cardiac murmur. He also described unil…
GMN 2738 · https://historyofmedicine.com/id/8654
1815 HODGSON, Joseph (1788 – 1869)
A treatise on the diseases of arteries and veins. 1 vol. and atlas.
Includes the best illustrations of aneurysms and of aortic valvular endocarditis so far published, and the first description on non-sacculated dilatation of the aortic arch (“Hodgson’s disease”).
GMN 2741 · https://historyofmedicine.com/id/4588
1835 BOUILLAUD, Jean Baptiste (1796 – 1881)
Traité cliniques des maladies du coeur. 2 vols.
Bouillaud applied Laennec's technique of auscultation to diseases of the heart. Vol. 2, page 238: “Bouillaud’s disease” – rheumatic endocarditis. Although not first to note the cardiac manifestations of acute rheumati…
GMN 2749 · https://historyofmedicine.com/id/4633
1840 BOUILLAUD, Jean Baptiste (1796 – 1881)
Traité clinique du rhumatisme articulaire.
Extension of Bouillaud’s work on the coincidence of heart disease and acute rheumatism. He regarded fever as the effect of endocarditis (see also No. 2749).
GMN 4494 · https://historyofmedicine.com/id/93
1843 BARLOW, George Hilaro (1806 – 1866); REES, George Owen (1813 – 1889)
Account of observations… on patients whose urine was albuminous.
An early description of a case of subacute bacterial endocarditis is reported on pp. 227-32 (Case 8).
GMN 2753 · https://historyofmedicine.com/id/4645
1869 WINGE, Emanuel Fredrik Hagbarth (1827 – 1894)
Mycosis endocardii.
Winge first suggested that endocarditis was due to microbial infection. A translation of part of his paper is in Major, Classic descriptions of disease, 3rd ed., 1945, p. 472.
GMN 2767 · https://historyofmedicine.com/id/4700
1870 WILKS, Sir Samuel (1824 – 1911)
Capillary embolism or arterial pyaemia.
One of the first accounts of bacterial endocarditis was given by Wilks, who, in his classic paper on the subject, called the condition “arterial pyaemia.” Reprinted in Willius & Keys, Cardiac classics, 1941, pp. 579-84.
GMN 2769 · https://historyofmedicine.com/id/4702
1872 HEIBERG, Hjalmar (1837 – 1897)
Ein Fall von Endocarditis ulcerosa puerperalis mit Pilzbildungen im Herzen (Mycosis endocardii).
Heiberg suggested the microbic nature of endocarditis. He described what appeared to him to be the mycelia of Leptothrix in the vegetations of a case of ulcerative endocarditis.
GMN 2774 · https://historyofmedicine.com/id/4719
1885 OSLER, Sir William (1849 – 1919)
The Gulstonian Lectures, on malignant endocarditis.
First comprehensive description of subacute bacterial endocarditis.
GMN 2790 · https://historyofmedicine.com/id/3396
1896 THAYER, William Sydney (1864 – 1932); BLUMER, George Alder (1857 – 1940)
Ulcerative endocarditis due to the gonococcus; gonorrheal septicemia.
Thayer and Blumer found the gonococcus in cases of gonorrheal endocarditis.
GMN 5212 · https://historyofmedicine.com/id/7812
1908 –1909 OSLER, Sir William (1849 – 1919)
Chronic infectious endocarditis.
The tender subcutaneous nodes in subacute bacterial endocarditis (“Osler’s nodes”) were first observed by Osler in 1888, and reported in 1909. This paper is the first definite clinical description of subacute bacteria…
GMN 2827 · https://historyofmedicine.com/id/3538
1909 BRACHT, Erich Frans Eugen (1882 – 1969); WÄCHTER, Hermann Julius Gustav (1878 – 1944)
Beitrag zur Aetiologie und pathologischen Anatomie der Myokarditis rheumatica.
“Bracht–Wächter bodies” in the myocardium in bacterial endocarditis.
GMN 2828 · https://historyofmedicine.com/id/3543
1909 HORDER, Thomas Jeeves (1871 – 1955)
Infective endocarditis, with an analysis of 150 cases.
Classic description of subacute bacterial endocarditis.
GMN 2829 · https://historyofmedicine.com/id/3546
1910 LIBMAN, Emanuel (1872 – 1946); CELLER, Herbert Louis (1878 – 1928)
The etiology of subacute infective endocarditis.
Libman and Celler found Strep. endocarditis to be the most common cause of subacute bacterial endocarditis.
GMN 2834 · https://historyofmedicine.com/id/3560
1910 SCHOTTMÜLLER, Hugo (1867 – 1936)
Endocarditis lenta. Zugleich ein Beitrag zur Artunterscheidung der pathogenen Streptokokken.
First to isolate Strep viridans in cases of bacterial endocarditis, Schottmüller named the condition Endocarditis lenta.
GMN 2836 · https://historyofmedicine.com/id/3569
1912 BAEHR, George (1887 – 1978)
Glomerular lesions of subacute bacterial endocarditis.
Baehr drew attention to the renal lesions in subacute bacterial endocarditis.
GMN 2838 · https://historyofmedicine.com/id/3574
1912 LIBMAN, Emanuel (1872 – 1946)
A study of the endocardial lesions of subacute bacterial endocarditis.
GMN 2841 · https://historyofmedicine.com/id/3589
1924 LIBMAN, Emanuel (1872 – 1946); SACKS, Benjamin (1896 – 1939)
A hitherto undescribed form of valvular and mural endocarditis.
“Libman–Sacks disease”.
GMN 2855 · https://historyofmedicine.com/id/3645
1935 BAEHR, George (1887 – 1978)
A diffuse disease of the peripheral circulation (usually associated with lupus erythematosus and endocarditis).
See No. 2237. With P. Klemperer and A. Schifrin.
GMN 2236 · https://historyofmedicine.com/id/3804
1948 CHRISTIE, Ronald Victor (1902 – 1986)
Penicillin in subacute bacterial endocarditis. Report to the Medical Research Council on 269 patients treated in 14 centres appointed by the Penicillin Clinical Trials Committee.
GMN 2880 · https://historyofmedicine.com/id/4224
