2016 LEMEY, Phillippe; WOROBEY, Michael; WATTS, Thomas D.; MCKAY, Richard A.; ET AL
1970s and 'Patient 0' HIV-1 genomes illuminate early HIV/AIDS history in North America.
By genetic analysis of HIV, Worobey, Lemey and colleagues from the social sciences "cleared" Gaëtan Dugas, a Canadian air steward, who previously had been identified by name as Patient Zero--the source of the epidemic…
GMN 10779 · https://historyofmedicine.com/id/12975
2016 PRITT, Bobbi S.; JOHNSON, Diep K. Hoang; MEAD, Paul S.; ET AL
Identification of a novel pathogenic Borrelia species causing Lyme borreliosis with unusually high spirochaetemia: A descriptive study.
Order of authorship in the original publication: Pritt, Mead, Johnson. Discovery of Lyme Borreliosis or Borrelia mayonii, a new variant of B. burgdorferi. (Thanks to Juan Weiss for this reference and its interpretation.)
GMN 10922 · https://historyofmedicine.com/id/13118
2016 BREMAN, Joel G.; HEYMANN, David L.; LLOYD, Graham; ET AL
Discovery and description of Ebola Zaire virus in 1976 and relevance to the West African epidemic during 2013-2016.
A first hand account of events as they occurred in Yambuku in 1976, including the causes and reasons for the spread of Ebola within the Yambuku Mission hospital, the probable index event/patient (not identified), and …
GMN 10925 · https://historyofmedicine.com/id/13121
2016 SIROHI, Devika; KUHN, Richard J.; ROSSMANN, Michael G. (1930 – 2019); ET AL
The 3.8Å resolution cryo-EM structure of Zika Virus.
Order of authorship in the original paper: Sirohi, Rossmann, Kuhn. Using cryogenic-electron microscopy (cryo-EM), the authors presented the molecular structure of the Zika virus at 3.8Å resolution. Digital facsimile f…
GMN 10941 · https://historyofmedicine.com/id/13137
2016 DUTRA, Heverton Leandor Carneiro; ROCHA, Marcele Neves; MOREIRA, Luciano Andrade; ET AL
Wolbachia blocks currently circulating Zika virus isololates in Brazilian Aedes aegypti mosquitoes.
Order of authorship in the original paper: Dutra, Rocha, Moreira. The authors infected lab populations of mosquitos with Wolbachia pipientis, a common parasitic microbe that infects a high proportion of insects. They …
GMN 10942 · https://historyofmedicine.com/id/13138
2016 CENTERS FOR DISEASE CONTROL AND PREVENTION (CDC)
Local mosquito-borne transmission of Zika virus - Miami - Dade and Broward counties, Florida, June-August 2016.
First report on Zika virus infections in the U.S., tracing the area of infection to a specific square mile, creating a buffer zone around the area, targeting it for spraying and mosquito collection, intervention, mass…
GMN 10944 · https://historyofmedicine.com/id/13140
2016 MULANGU, Sabue; CORTI, Davide; MISASI, John; ET AL
Protective monotherapy against lethal Ebola virus infection by a potently neutralizing antibody.
The cited paper was immediately followed in the same issue of Science by: John Misasi, Morgan A. Gilman, Masaru Kanekiyo et al, "Structural and molecular basis for Ebola virus neutralization by protective human antibo…
GMN 11375 · https://historyofmedicine.com/id/13574
2016 GRANDE, Laura; MICHELACCI, Valeria; BONDI, Roslen; ET AL
Whole-genome characterization and strain comparison of VT2f-producing Escherichia coli causing hemolytic uremic syndrome.
Order of authorship in the original publication: Grande, Michelacci, Bondi.... Demonstration that a phage infecting E. coli conveys the genes into the E. coli that code for the production of the verotoxin that causes …
GMN 11409 · https://historyofmedicine.com/id/13608
2016 DIOKNO, Maria Serena Icasiano
Hidden lives, concealed narratives: A history of leprosy in the Philippines. Edited by Maria Serena I. Diokno.
GMN 11437 · https://historyofmedicine.com/id/13636
2016 DELACY, Margaret
The germ of an idea: Contagionism, religion, and society in Britain, 1660-1730.
"Contagionism is an old idea, but gained new life in Restoration Britain. The Germ of an Idea considers British contagionism in its religious, social, political and professional context from the Great Plague of London…
GMN 13089 · https://historyofmedicine.com/id/15341
2016 MARKEL, Howard (1960 – ); NAVARRO, J. Alexander
Influenza encyclopedia: The American influenza epidemic of 1918 - 1919: A digital encyclopedia. Second edition.
ABOUT "Historians, journalists, and the public at large have long been interested in the 1918 “Spanish flu” epidemic, a dramatic chapter in American life that has spawned an impressive body of books, articles, and mul…
GMN 14068 · https://historyofmedicine.com/id/16379
2017 SPINNEY, Laura
Pale Rider: The Spanish flu of 1918 and how It changed the world.
GMN 9691 · https://historyofmedicine.com/id/11878
2017 CZERWIEC, M. K.
Taking turns: Stories from HIV/AIDS Care Unit 371.
"In 1994, at the height of the AIDS epidemic in the United States, MK Czerwiec took her first nursing job, at Illinois Masonic Medical Center in Chicago, as part of the caregiving staff of HIV/AIDS Care Unit 371. Taki…
GMN 9828 · https://historyofmedicine.com/id/12016
2017 WENC, Christine
HIV / AIDS Collected by: National Library of Medicine, Christine Wenc, curator.
https://archive-it.org/collections/8400 HIV/AIDS "A collection of websites selected and archived by the National Library of Medicine on biomedical, clinical, cultural, and social aspects of HIV/AIDS in the early 21st …
GMN 9958 · https://historyofmedicine.com/id/12147
2017 PRITT, Bobbi S.; SLOAN, Lynn M.; ALLERDICE, Michelle E. J.; ET AL
Proposal to reclassify Ehrlichia muris as Ehrlichia muris subsp. muris subsp. nov. and description of Ehrlichia muris subsp. eauclairensis subsp. nov., a newly recognized tick borne pathogen of humans.
Order of authorship in the original publication: Pritt, Allderdice, Sloan. By extremely complex genotyping methods and fine electron microscopic analysis of the organism, the authors showed that the infectious agent i…
GMN 10906 · https://historyofmedicine.com/id/13102
2017 GRUBAUGH, Nathan D.; LADNER, Jason T.; KRAEMER, Moritz U.G.; ET AL
Genomic epidemiology reveals multiple introductions of Zika virus into the United States.
Order of authorship in the original publication: Grubaugh, Ladner, Kraemer. The authors found that the Zika virus was introduced into Florida at least 4 times, but perhaps as many as 40 times, before it was detected, …
GMN 10945 · https://historyofmedicine.com/id/13141
2017 CLEMENTS, Alan N.; HARBACH, Ralph E.
History of the discovery of the mode of transmission of yellow fever virus.
Digital text is available from Wiley Online Library at this link.
GMN 11861 · https://historyofmedicine.com/id/14065
2017 DELACY, Margaret
Contagionism catches on. Medical ideology in Britain, 1730-1800.
"This book shows how contagionism evolved in eighteenth century Britain and describes the consequences of this evolution. By the late eighteenth century, the British medical profession was divided between traditionali…
GMN 13088 · https://historyofmedicine.com/id/15340
2017 PIETRZAK-FRANGER, Monika
Syphilis in Victorian literature and culture: Medicine, knowledge and the spectacle of invisibility.
GMN 13910 · https://historyofmedicine.com/id/16203
2017 KARIKÓ, Katalin (1955 – ); WEISSMAN, Drew; PARDI, Norbert; ET AL
Zika virus protection by a single low-dose nucleoside-modified mRNA vaccination.
Prior to their development of the mRNA vaccine for Covid-19, Karikó and Weissman (Nobel Prize 2023) and colleagues used a novel mRNA vaccine, with base modifications created in their laboratory, to generate a protecti…
GMN 14201 · https://historyofmedicine.com/id/16517
2018 FRANCIS A. COUNTWAY LIBRARY OF MEDICINE
CONTAGION: Historical views of diseases and epidemics.
http://ocp.hul.harvard.edu/contagion/ This was the original version of this digital library. It includes commentary. It may be available through the Internet Archive, Archive-It facility or through the Wayback Machine…
GMN 9959 · https://historyofmedicine.com/id/12148
2018 MURRAY, John F.; LODDENKEMPER, Robert (1939 – )
Tuberculosis and War: Lessons learned from World War II. Edited by John F. Murray and Robert Loddenkemper.
This book provides a comprehensive analysis of the status of TB before, during and after WWII in the 25 belligerent countries that were chiefly involved. It also summarizes the history of TB up to the present day. "A …
GMN 10594 · https://historyofmedicine.com/id/12787
2018 MANN, Annika
Reading contagion: The hazards of reading in the age of print.
GMN 10935 · https://historyofmedicine.com/id/13131
2018 PIERSON, Theodore C.; DIAMOND, Michael
The emergence of Zika virus and its new clinical syndromes.
Order of authorship in the original publication: Pierson, Diamond. Analyzes, and documents with 147 references, the variety of new clinical syndromes, including fetal / in utero effects, caused by the Zika virus. Also…
GMN 10946 · https://historyofmedicine.com/id/13142
2018 FOLEY, Paul Bernard
Encephalitis lethargica: The mind and brain virus.
Both an historical and a scientific study.
GMN 12636 · https://historyofmedicine.com/id/14877
2019 DHINGRA, Akshay; GABZENMULLER, Tina; HAGE, Elias; ET AL
Novel virus related to Kaposi's Sarcoma associated herpesvirus from Colobus monkey.
Discovery of a new Karposi's Sarcoma virus in monkeys, named CbGHV1. Autopsy showed that the monkey died from a "primary effusion lymphoma" similar to the deaths of humans from human Karposi Sarcoma virus. (Thanks to …
GMN 10912 · https://historyofmedicine.com/id/13108
2019 GREWER, Anna; BLEYER, Martina; MATZ-RENSING, Kerstin; ET AL
Kaposi sarcoma in mantled guereza.
Order of authorship in original publication: Grewer, Bleyer, Matz-Rensing. Further work on the CBGHV1 (Colobine gammherpesvirus 1) which causes a pathology in the Colobus monkey very similar to that seen humans. (Than…
GMN 10913 · https://historyofmedicine.com/id/13109
2019 WANG, Ze-Dong; WANG, Bo; WEI, Feng; ET AL
A new segmented virus associated with human febrile illness in China.
Order of authorship in the original paper: Wang, Ze-Dong; Wang, Bo; Wei, Feng. Discovery of a new tick-borne virus that the authors name the "Alongshan virus" (ALSV) in the family Flaviridae. Digital facsimile from ne…
GMN 10916 · https://historyofmedicine.com/id/13112
2019 MULANGU, Sabue; DODD, Lori E.; DAVEY, Richard T. Jr.; ET AL
A randomized, controlled trial of Ebola virus disease therapeutics.
Order of authorship in the original publication: Mulangu, Dodd, Davey.... One synthetic drug (Remdesivir, an antiviral) and 3 biologicals were used in this trial. The 3 biologicals were: REGN-EB3, a triple monoclonal …
GMN 11374 · https://historyofmedicine.com/id/13573
2019 UPRETY, Priyanka; CURTIS, Darcy; ELKAN, Michael; GRAF, Erin H.; ET AL
Association of enterovirus D68 with Acute flaccid myelitis, Philadelphia, Pennsylvania, USA, 2009-2018.
The authors correlated increases of Acute Flaccid Myelitis (AFM) with EV-D68 outbreaks. They noted that EV-D68 infected mice exhibited paralyzed limbs, and they reported that EV-D68 had undergone genome evolutiion tha…
GMN 12715 · https://historyofmedicine.com/id/14961
2019 SKELTON, James W. Jr.
Eradicating smallpox in Ethiopia. Peace Corps Volunteers' Accounts of their Advantures, Challenges and Achievements. Edited by James W. Skelton, Gene L. Bartley, John Scott Porterfield, Alan Schnur.
GMN 13797 · https://historyofmedicine.com/id/16084
2020 GILSDORF, Janet R.
Continual raving: A history of meningitis and the people who conquered it.
GMN 12013 · https://historyofmedicine.com/id/14221
2020 FEDER, Henry M. Jr.; REZUKE, William N.
Infectious mononucleosis diagnosed by Downey cells: Sometimes the old ways are better.
The Downey cell method for the diagnosis of infectious mononucleosis remains effective and cost-effective nearly 100 years after it was discovered: "An 18-year-old woman visited her physician because she had a fever, …
GMN 12117 · https://historyofmedicine.com/id/14326
2020 RADIN, Jennifer Michalove; WINEINGER, Nathan E.; TOPOL, Eric Jeffrey (1954 – ); STEINHUBL, Stephen R.
Harnessing wearable device data to improve state-level real-time surveillance of influenza-like illness in the USA: A population-based study.
Order of authorship in the original publication: Radin, Wineinger, Topol, Steinhubl. "Background "Acute infections can cause an individual to have an elevated resting heart rate (RHR) and change their routine daily ac…
GMN 12182 · https://historyofmedicine.com/id/14392
2020 INGHAM, Victoria A.; ANTHOUSI, Amalia; DOURIS, Vassilis; ET AL
A sensory appendage protein protects malaria vectors from pyrethroids.
Researching how the malarial mosquito A. gambiae developed resistance to common pyrethroid insecticides, the authors discovered how natural selection had enabled this insect population to develop resistance. They anal…
GMN 12596 · https://historyofmedicine.com/id/14836
2020 JIANG, Chenyang; LIAN, Xiadong; GAO, Ce; ET AL
Distinct viral reservoirs in individuals with spontaneous control of HIV-1.
The authors describe a mechanism for the observed natural viral "immunity" of individuals with spontaneous control of HIV-1. A very few exceptional people have the molecular ability to steer the incoming/infecting cel…
GMN 13479 · https://historyofmedicine.com/id/15753
2020 WRAPP, Daniel; WANG, Nianshuang; CORBETT, Kizzmekia Shanta (1986 – ); GRAHAM, Barney S.; ET AL
Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation.
Posted online on February 17, 2020. 2019-nCoV was an interim name for the Novel Coronavirus. These studies, which included the 3D structure of the RBD (receptor binding domain) within the S protein, provided informati…
GMN 13483 · https://historyofmedicine.com/id/15757
2020 SHIN, Matthew D.; SHUKLA, Sourabh; CHUNG, Young Hun; STEINMETZ, Nicole F.; ET AL
COVID-19 vaccine development and a potential nanomaterial path forward.
Published 15 July 2020. Order of authorship in original publication: Shin, Shukla, Chung....Steinmetz. Probably the first publication on the type of nanotechnology involved in production of the Moderna and Pfizer mRNA…
GMN 13484 · https://historyofmedicine.com/id/15758
2020 POLACK, Fernando P.; THOMAS, Stephen J.; KITCHIN, Nicholas; ET AL
Safety and efficacy of the BNT162b2 mRNA Covid-19 vaccine.
BNT162b2 is synonomous with the Pfizer BioNTech mRNA Covid-19 vaccine. The Pfizer-BioNTech mRNA vaccine was produced from theoretical design to finished product and distribution in less than one year. This was the fir…
GMN 13506 · https://historyofmedicine.com/id/15781
2020 ROTHE, Camilla (1974 – ); SCHUNK, Mirjam; SOTHMANN, Peter; ET AL
Correspondence. Transmission of 2019 nCoV infection from an asymptomatic contact in Germany.
Posted online 1-30-20, updated 2-6-20, and published in print on March 5, 2020. First report of the "asymptomatic transmission" of Covid-19. The authors wrote, “The fact that asymptomatic persons are potential sources…
GMN 13519 · https://historyofmedicine.com/id/15794
2020 JONES, Veena Goel; MILLS, Marcos; SUAREZ, Dominique Marie; ET AL
Covid-19 and Kawasaki disease: Novel virus and novel case.
Published online 4-7-20; in print in June, 2020. First case report of what became known as Multisystem Inflammatory Syndrome in Children (MIS-C), sometimes present with Kawasaki disease. This is one of the worst compl…
GMN 13520 · https://historyofmedicine.com/id/15795
2020 BAUM, Alina; AJITHDOSS, Dharani K.; KYRATSOUS, Christos A.; ET AL
REGN-COV2 antibodies prevent and treat SARS-CoV-2 infection in rhesus macaques and hamsters.
The authors, working at Regeneron, showed that a cocktail of two potent neutralizing monoclonal antibodes reduced virus load in the airways and diminshed viral induced pathological sequelae when given both as a prophy…
GMN 13523 · https://historyofmedicine.com/id/15799
2020 ROYLES, Dan
To make the wounded whole: The African American struggle against HIV/AIDS.
GMN 13725 · https://historyofmedicine.com/id/16009
2020 FARMER, Paul Edward (1959 – 2022)
Fevers, feuds, and diamonds: Ebola and the ravages of history.
"Farmer first visited the Western African Ebola virus epidemic site in July 2014, and much of the book is devoted to his personal experiences. Reviewing the outbreak in 2020, he noted that there were almost no Ebola d…
GMN 14154 · https://historyofmedicine.com/id/16469
2021 ALBRECHT, Donald; LACHER-FELDMAN, Jessica; VALENTI, William Michael
Up against the wall: Art, activism, and the AIDS poster. Edited by Donald Albrecht and Jessica Lacher-Feldman. Medical and consulting editor William M. Valenti.
Documents the power and impact of nearly 200 examples of AIDS posters from around the world and the social activism that continues to bring awareness to a disease without vaccine or a cure. Selected from the 8000 post…
GMN 13373 · https://historyofmedicine.com/id/15644
2021 BADEN, Lindsey Robert; EL SAHLY, Hana M.; ESSINK, Brandon; ET AL
Efficacy and safety of the mRNA-1273 SARSCov-2 vaccine.
mRNA-1273 is synonymous with the Moderna mRNA Covid-19 vaccine. The Moderna mRNA vaccine was produced from theoretical design to finished product and distribution in less than one year. This was the first published pa…
GMN 13507 · https://historyofmedicine.com/id/15782
2021 WEINREICH, David. M.; SIVAPALASINGAM, Sumathi; NORTON, Thomas; ET AL
REGN-COV-2, a neutralizing antibody cocktail, in outpatients with Covid-19.
The authors showed that the Regeneron antibody cocktail has a low incidence of side effects and a profound and rapid effect on viral load, with most reduction occurring within 48 hours, even in patents with the highes…
GMN 13524 · https://historyofmedicine.com/id/15800
2022 SCHWARTZ, David Alan (1953 – ); AVVAD-PORTARI, Elyzabeth; BABÁL, Pavel; ET AL
Placental tissue destruction and insufficiency from COVID-19 causes stillbirth and neonatal death from hypoxic-ischemic injury: A study of 68 cases with SARS-CoV-2 placentitis from 12 countries.
Order of authorship in the original publication: Schwartz, Avvad-Portari, Babál, et al.... "Design.—Case-based retrospective clinico-pathological analysis by a multinational group of 44 perinatal specialists from 12 c…
GMN 13814 · https://historyofmedicine.com/id/16103
2022 WEHRMAN, Andrew M.
The contagion of liberty: The politics of smallpox in the American revolution.
"The Revolutionary War broke out during a smallpox epidemic, and in response, General George Washington ordered the inoculation of the Continental Army. But Washington did not have to convince fearful colonists to pro…
GMN 14090 · https://historyofmedicine.com/id/16401
2022 LEMEY, Phillippe; WOROBEY, Michael; LEVY, Joshua I.; ET AL
The Huanan seafood wholesale market in Wuhan was the early epicenter of the COVID-19 pandemic.
Worobey and colleagues showed: 1) The earliest case of an abnormal pneumonia was first reported to the World Health Organization on Dec. 31, 2019. 2) Using basic epidemiology going back to the now iconic plot maps dra…
GMN 14168 · https://historyofmedicine.com/id/16483
