1900 CALOT, Jean François (1861 – 1944)
Les maladies qu’on soigne à Berck.
An account of the work of the Rothschild Hospital at Berck-sur-Mer, where Calot specialized in the treatment of surgical tuberculosis in children.
GMN 2336 · https://historyofmedicine.com/id/3076
1902 MENDENHALL, Dorothy Mabel Reed (1874 – 1964)
On the pathological changes in Hodgkin’s disease, with especial reference to its relation to tuberculosis.
Dorothy Reed’s classic work on Hodgkin’s disease included a study of the histological picture. She described the proliferation of the endothelial and reticular cells, and the formation of lymphadenoma cells – “Dorothy…
GMN 3780 · https://historyofmedicine.com/id/4677
1907 CALMETTE, Léon Charles Albert (1863 – 1933)
Sur un nouveau procédé de diagnostic de la tuberculose chez l’homme par l’ophtalmo-reaction à la tuberculine.
Calmette’s conjunctival reaction test for tuberculosis.
GMN 2337 · https://historyofmedicine.com/id/3077
1907 PIRQUET, Clemens Peter Freiherr von (1874 – 1929)
Der diagnostische Wert der kutanen Tuberkulinreaktion bei der Tuberkulose des Kindesalters auf Grund von 100 Sektionen.
Introduction of Pirquet’s test – a cutaneous reaction employed in the diagnosis of tuberculosis.
GMN 2338 · https://historyofmedicine.com/id/3080
1908 MORO, Ernst (1874 – 1951)
Ueber eine diagnostische verwertbare Reaktion der Haul auf Einreibung mit Tuberkulinsalbe.
Moro’s percutaneous tuberculin reaction, employed as a diagnostic measure.
GMN 2339 · https://historyofmedicine.com/id/3083
1908 WOLFF-EISNER, Alfred (1877 – 1948)
Die kutane und konjunktivale Tuberkulinreaktion, ihre Bedeutung für Diagnostik und Prognose der Tuberkulose.
Wolff-Eisner’s conjunctival tuberculin reaction.
GMN 2340 · https://historyofmedicine.com/id/3086
1908 MANTOUX, Charles (1877 – 1947)
Intradermo-réaction de la tuberculine.
Mantoux’s intradermal tuberculin skin test.
GMN 2341 · https://historyofmedicine.com/id/3089
1908 MENDEL, Felix (1862 – 1925)
Die von Pirquet'sche Hautreaktion und die intravenöse Tuberkulinbehandlung.
First publication on the The Mantoux test or Mendel–Mantoux test (also known as the Mantoux screening test, tuberculin sensitivity test, Pirquet test, or PPD test for purified protein derivative) is a tool for screeni…
GMN 12385 · https://historyofmedicine.com/id/14611
1909 OTIS, Edward Osgood (1848 – 1943)
The great white plague: Tuberculosis.
Digital facsimile from Google Books at this link.
GMN 13476 · https://historyofmedicine.com/id/15750
1910 SMITH, Sir Grafton Elliot (1871 – 1937); RUFFER, Sir Marc Armand (1859 – 1917)
Pott’sche Krankheit an einer ägyptischen Mumie.
The fact that tuberculosis was present among the ancient Egyptians was proved when Elliot Smith and Ruffer described a genuine case of Pott’s disease in a mummy of 1000 B.C.E.
GMN 2320 · https://historyofmedicine.com/id/3013
1911 CRAWFURD, Sir Raymond Henry Payne (1865 – 1938)
The king’s evil.
A classic account of the history of touching for the “king’s evil” or scrofula— a practice of kings from ancient times until the 18th century.
GMN 6646 · https://historyofmedicine.com/id/7769
1912 KOCH, Robert Heinrich Hermann (1843 – 1910); GAFFKY, Georg Theodor August (1850 – 1918); SCHWALBE, Julius (1866 – 1930); PFUHL, Ernst (1876 – 1940)
Gesammelte Werke von Robert Koch. Unter Mitwirkung von G. Gaffky and E. Pfuhl. Herausgegeben von J. Schwalbe. 2 vols. [in 3).
For his work on tuberculosis Koch received the Nobel Prize in 1905. Digital facsimile from the Internet Archive at this link. See T.D. Brock, Robert Koch: A life in medicine and bacteriology, Madison, WS: Science-Tech…
GMN 86 · https://historyofmedicine.com/id/1437
1913 ROLLIER, Auguste (1874 – 1954)
Die Heliotherapie der Tuberkulose.
In 1903 Rollier introduced ultra-violet light and Alpine sunlight in the treatment of surgical tuberculosis. Heliotherapy for chronic affections was advocated as early as the 5th century CE by Caelius Aurelianus.
GMN 2342 · https://historyofmedicine.com/id/3091
1915 ALBEE, Fred Houdlett (1876 – 1945)
Bone-graft surgery.
Albee was the first to employ living bone grafts as internal splints. He used cutting machines and saws to make inlaid, perfectly-fitting grafts. See especially his “Transplantation of a portion of the tibia into the …
GMN 5757 · https://historyofmedicine.com/id/6678
1924 CALMETTE, Léon Charles Albert (1863 – 1933); GUÉRIN, Camille (1872 – 1961); WEILL-HALLÉ, Benjamin (1875 – 1958); ET AL
Essai d’immunisation contre l’infection tuberculeuse.
B.C.G. (Bacille Calmette–Guérin) vaccine was first produced in 1906 and subcultured for 13 years. It was first used as a prophylactic against tuberculosis in children in 1921. It remains in use. See also No. 2346.
GMN 2343 · https://historyofmedicine.com/id/3094
1925 MØLLGAARD, Holger (1885 – 1973)
Ueber die experimentellen Grundlagen für die Sanocrysin-Behandlung der Tuberkulose.
Mollgaard was responsible for the introduction of sanocrysin.
GMN 2344 · https://historyofmedicine.com/id/3099
1925 FLICK, Lawrence Francis (1856 – 1938)
Development of our knowledge of tuberculosis.
GMN 2354 · https://historyofmedicine.com/id/3153
1926 SAUERBRUCH, Ernst Ferdinand (1875 – 1951); GERSON, Max (1881 – 1959); ET AL
Ueber Versuche, schwere Formen der Tuberkulose durch diätetische Behandlung zu beeinflussen.
Gerson introduced a salt-restricted diet in the treatment of tuberculosis; this was subsequently modified by Sauerbruch and Herrmannsdorfer, becoming known as the “Gerson–Sauerbruch–Hermannsdorfer diet”. The scientifi…
GMN 2345 · https://historyofmedicine.com/id/3102
1926 SEIBERT, Florence Barbara (1897 – 1991)
Isolation of a crystalline protein with tuberculin activity.
Siebert identified the active agent in tuberculin as a protein.
GMN 12386 · https://historyofmedicine.com/id/14613
1927 CALMETTE, Léon Charles Albert (1863 – 1933); GUÉRIN, Camille (1872 – 1961); BOQUET, Alfred (1879 – 1947); NÈGRE, Léopold (1879 – 1961)
Sur la vaccination préventive des enfants nouveau-nés contre la tuberculose par le B.C.G.
GMN 2346 · https://historyofmedicine.com/id/3105
1927 CALMETTE, Léon Charles Albert (1863 – 1933); GUÉRIN, Camille (1872 – 1961); BOQUET, Alfred (1879 – 1947); NÈGRE, Léopold (1879 – 1961)
La vaccination préventive contre la tuberculose par le "BGG". Par Albert Calmette avec la collaboration de C. Guérin, A. Boquet et L. Nègre.
A 250-page monograph, with bibliographical references, on the development of the BCG vaccine from M. bovis, from 1909 to 1927 by the scientists involved. (Thanks to Ron Cox for this reference.)
GMN 11994 · https://historyofmedicine.com/id/14202
1931 PIÉRY, Antoine Marius (1873 – 1957); ROSHEM, Julien
Historie de la tuberculose.
GMN 2355 · https://historyofmedicine.com/id/3156
1932 LONG, Esmond Ray (1890 – 1979); WELLS, Henry Gideon (1875 – 1943)
The chemistry of tuberculosis. Second edition.
GMN 2347 · https://historyofmedicine.com/id/3109
1934 SEIBERT, Florence Barbara (1897 – 1991)
The isolation and properties of the purified protein derivative of tuberculin
Purification of tuberculin (PPD). By the 1940s Seibert's PPD was the international standard for tuberculin tests.
GMN 12387 · https://historyofmedicine.com/id/14614
1936 MEACHEN, George Norman (1876 – )
A short history of tuberculosis.
GMN 2356 · https://historyofmedicine.com/id/3158
1936 WEBB, Gerald Bertram (1871 – 1948)
Tuberculosis.
Clio Medica series.
GMN 2357 · https://historyofmedicine.com/id/3162
1936 FLEXNER, Abraham (1866 – 1959); HESS, Alfred Fabian (1875 – 1933)
Collected writings. With a biographical memoir by Abraham Flexner. 2 vols.
GMN 13044 · https://historyofmedicine.com/id/15295
1937 VOLLMER, Hermann (1896 – 1959); GOLDBERGER, Esther White (1905 – )
A new tuberculin patch test.
GMN 2348 · https://historyofmedicine.com/id/3118
1937 KAYNE, George Gregory (1901 – 1945)
The control of tuberculosis in England, past and present.
GMN 2358 · https://historyofmedicine.com/id/3165
1940 FELDMAN, William Hugh (1892 – 1974); ET AL
The effect of promin (sodium salt of P. P’-diamino-diphenyl-sulfone-N, N’-dextrose sulfonate) on experimental tuberculosis: a preliminary report.
Experimental evidence of the value of promin (sodium glucosulphone) in tuberculosis. With H. C. Hinshaw and H.E. Moses. See also Amer. Rev. Tuberc., 1942, 45, 303-33.
GMN 2349 · https://historyofmedicine.com/id/3120
1944 RICH, Arnold Rice (1893 – 1968)
The pathogenesis of tuberculosis.
Classic work on the pathogenesis of tuberculosis and its immunology and hypersensitivity.
GMN 2349.1 · https://historyofmedicine.com/id/3122
1945 FELDMAN, William Hugh (1892 – 1974); HINSHAW, Horton Corwin (1902 – 2001)
Streptomycin in treatment of clinical tuberculosis: a preliminary report.
GMN 2350 · https://historyofmedicine.com/id/3125
1946 DOMAGK, Gerhard Johannes Paul (1895 – 1964); ET AL
Ueber eine neue, gegen Tuberkelbazillen in vitro wirksame Verbindungsklasse.
Introduction of thiosemicarbazone in treatment of tuberculosis. With R. Behnisch, F. Mietzsch, and H. Schmidt.
GMN 2351 · https://historyofmedicine.com/id/3129
1946 HART, Philip Montagu D'Arcy (1900 – 2006)
Chemotherapy of tuberculosis. Researches during the past 100 years.
GMN 2359 · https://historyofmedicine.com/id/3167
1950 FRAPPIER, Armand (1904 – 1991); GUY, Roland (1913 – )
A new and practical B.C.G. skin test (the B.C.G. scarification test) for the detection of the total tuberculous allergy.
GMN 2352 · https://historyofmedicine.com/id/3132
1951 HEAF, Frederick Roland George (1894 – 1973)
The multiple-puncture tuberculin test.
The Heaf multiple-puncture tuberculin test.
GMN 2352.1 · https://historyofmedicine.com/id/3135
1952 ROBITZEK, Edward Heinrich (1912 – 1984); ET AL
Chemotherapy of human tuberculosis with hydrazine derivatives of isonicotinic acid. (Preliminary report of representative cases.)
Introduction of isoniazid. With I. J. Selikoff and G. G. Omstein. See also Amer. Rev. Tuberc., 1952, 65, 257-442.
GMN 2353 · https://historyofmedicine.com/id/3139
1955 BURKE, Richard Michael (1903 – )
Historical chronology of tuberculosis. 2nd ed.
GMN 2360 · https://historyofmedicine.com/id/3172
1956 GRIFFITHS, Margaret Isabel (1902 – 1996); GAISFORD, Wilfrid Fletcher (1902 – 1988)
Freeze-dried B.C.G. vaccination of newborn infants with a British vaccine.
Freeze-dried B.C.G. vaccine.
GMN 2353.1 · https://historyofmedicine.com/id/3142
1959 RIST, Noël (1906 – 1990); ET AL
Experiments on the antituberculous activity of alpha-ethyl-thioisonicotinamide.
Ethionamide. With F. Grumbach and D. Liberman.
GMN 2353.2 · https://historyofmedicine.com/id/3146
1961 THOMAS, J. P.; ET AL
A new synthetic compound with antituberculous activity in mice; ethambutol (dextro-2, 2’-(ethylenediimino)-di-l-butanol).
Ethambutol for the treatment of tuberculosis. With C. O. Baughn, R. G. Wilkinson and R. G. Shepherd.
GMN 2353.3 · https://historyofmedicine.com/id/3149
1995 BARNES, David S.
The making of a social disease: Tuberculosis in nineteenth-century France.
GMN 8036 · https://historyofmedicine.com/id/10212
1995 FELDBERG, Georgina D. (1956 – )
Disease and class: Tuberculosis and the shaping of modern North American society.
GMN 8103 · https://historyofmedicine.com/id/10279
1995 SØRENSON, Anne L.; NAGAI, Sadamu; HOUEN, Gunnar; ANDERSEN, Peter Lawaetz; ET AL
Purification and characterization of a low-molecular-mass T-cell antigen secreted by Mycobacterium tuberculosis.
Andersen and colleagues found that a protein fraction obtained from M. tuberculosis was immunologically active in mice, suggesting that it was one of the proteins recognized by T cells. In this paper the authors ident…
GMN 11997 · https://historyofmedicine.com/id/14205
1996 MAHAIRAS, Gregory G.; SABO, Peter J.; HICKEY, Mark J.; ET AL
Molecular analysis of genetic differences between Mycobacterium bovis BCG and virulent M. bovis.
Order of authorship in the original publication: Mahairas, Sabo, Hickey.... From the Abstract: "The live attenuated bacillus Calmette-Guérin (BCG) vaccine for the prevention of disease associated with Mycobacterium tu…
GMN 11995 · https://historyofmedicine.com/id/14203
1998 LERNER, Barron H. (1960 – )
Contagion and confinement: Controlling tuberculosis along the skid road.
GMN 9650 · https://historyofmedicine.com/id/11837
1998 COLE, S. T.; ET AL
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
Abstract: "Countless millions of people have died from tuberculosis, a chronic infectious disease caused by the tubercle bacillus. The complete genome sequence of the best-characterized strain of Mycobacterium tubercu…
GMN 11998 · https://historyofmedicine.com/id/14206
2003 FARMER, Paul Edward (1959 – 2022); KIDDER, John Tracy (1945 – )
Mountains beyond mountains: The quest of Dr. Paul Farmer, a man who would cure the world
Traces the life of physician and anthropologist Paul Farmer with particular focus on his work fighting tuberculosis, especially in Haiti, Peru, and Russia.
GMN 14155 · https://historyofmedicine.com/id/16470
2005 FORTUINE, Robert (1934 – 2009)
Must we all die? Alaska's enduring struggle with tuberculosis.
GMN 10080 · https://historyofmedicine.com/id/12269
2009 KOCH, Robert Heinrich Hermann (1843 – 1910); GRADMANN, Christoph
Laboratory disease: Robert Koch's medical bacteriology.
GMN 12384 · https://historyofmedicine.com/id/14609