1926 MAXCY, Kenneth Fuller (1889 – 1966)

Clinical observations on endemic typhus (Brill’s disease) in Southern United States.

Maxcy described murine (flea-borne) typhus (“Maxcy’s disease”).

GMN 5396 · https://historyofmedicine.com/id/7169

1926 BUER, M. C.

Health, wealth and population in the early days of the industrial revolution.

Chapters on water supply, 18th physicians and pioneers of public health, the hospital and dispensary movement, general hygiene and midwifery, rickets and scurvy, antiseptics, smallpox, anti-typhus campaign, malaria, etc.

GMN 10467 · https://historyofmedicine.com/id/12660

1928 MOOSER, Hermann (1891 – 1971)

Experiments relating to the pathology and the etiology of Mexican typhus (tabardillo).

Mooser differentiated murine from epidemic typhus. The causative organism was later named Rickettsia mooseri.

GMN 5396.1 · https://historyofmedicine.com/id/7173

1931 DYER, Rollo Eugene (1886 – ); ET AL

Typhus fever. A virus of the typhus type derived from fleas collected from wild rats.

Murine typhus shown to be caused by an organism later named Rickettsia mooseri, transmitted by fleas from rats to man. With A. Rumreich and L. F. Badger.

GMN 5396.2 · https://historyofmedicine.com/id/7175

1934 ZINSSER, Hans (1878 – 1940)

Varieties of typhus virus and the epidemiology of the American form of European typhus fever (Brill’s disease).

Zinsser advanced the theory that Brill’s disease is a recrudescence of epidemic typhus in persons who have contracted the typhus some time previously. The condition has subsequently been renamed “Brill-Zinsser disease”.

GMN 5396.4 · https://historyofmedicine.com/id/7180

1940 COX, Herald Rea (1907 – 1986); BELL, E. John

Epidemic and endemic typhus. Protective value for guinea pigs of vaccines prepared from infected tissues of the developing chick embryo.

Typhus vaccine.

GMN 5398.1 · https://historyofmedicine.com/id/7191

1940 LEWTHWAITE, Raymond (1894 – 1972); SAVOOR, S. R. (1900 – 1980)

Rickettsia disease of Malaya. Identity of tsutsugamushi and rural typhus.

Lewthwaite and Savoor showed scrub typhus to be identical to tsutsugamushi fever.

GMN 5398.2 · https://historyofmedicine.com/id/7195

1944 YEOMANS, Andrew (1907 – ); ET AL

The therapeutic effect of para-aminobenzic acid in louse-borne typhus fever.

With J. C. Snyder, E. S. Murray, C. J. D. Zarafonetis, and R. S. Ecke.

GMN 5398.3 · https://historyofmedicine.com/id/7199

1945 FULTON, Forrest (1913 – 1971); JOYNER, L

Cultivation of Rickettsia tsutsugamushi in lungs of rodents. Preparation of a scrub-typhus vaccine.

Scrub-typhus vaccine.

GMN 5399 · https://historyofmedicine.com/id/7205

1947 SMADEL, Joseph Edwin (1907 – 1963); JACKSON, Elizabeth B.

Chloromycetin, an antibiotic with chemotherapeutic activity in experimental rickettsial and viral infections.

Introduction of chloramphenicol, used in treatment of typhus.

GMN 1940 · https://historyofmedicine.com/id/8617